Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Avi Schroeder"'
Autor:
Eli BenDavid, Sina Ramezanian, Yaoyao Lu, Joël Rousseau, Avi Schroeder, Marc Lavertu, Jacques P. Tremblay
Publikováno v:
Pharmaceuticals, Vol 17, Iss 6, p 763 (2024)
Prime editing shows potential as a precision genome editing technology, as well as the potential to advance the development of next-generation nanomedicine for addressing neurological disorders. However, turning in prime editors (PEs), which are macr
Externí odkaz:
https://doaj.org/article/09d0d33510234dd399a4bb216167add3
Publikováno v:
Vaccines, Vol 12, Iss 3, p 282 (2024)
In this study, we consider the influence of biological sex-specific immune responses on the assessment of mRNA vaccines in pre-clinical murine studies. Recognising the established disparities in immune function attributed to genetic and hormonal diff
Externí odkaz:
https://doaj.org/article/e14ac5a7f57b4608a7da8a3489f44555
Autor:
Omer Adir, Mia R. Albalak, Ravit Abel, Lucien E. Weiss, Gal Chen, Amit Gruber, Oskar Staufer, Yaniv Kurman, Ido Kaminer, Jeny Shklover, Janna Shainsky-Roitman, Ilia Platzman, Lior Gepstein, Yoav Shechtman, Benjamin A. Horwitz, Avi Schroeder
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Synthetic biology and engineering approaches are harnessed to incorporate new capabilities in synthetic cells. Here, the authors designed bioluminescent signaling mechanisms for intracellular and intercellular synthetic-to-natural cell communication.
Externí odkaz:
https://doaj.org/article/f081c2771b204a69ba9f89ea10bf1504
Autor:
Sebastian Schötz, Adele K. Griepe, Björn B. Goerisch, Sally Kortam, Yael Shammai Vainer, Mathias Dimde, Hanna Koeppe, Stefanie Wedepohl, Elisa Quaas, Katharina Achazi, Avi Schroeder, Rainer Haag
Publikováno v:
Pharmaceuticals, Vol 16, Iss 11, p 1618 (2023)
Rare gastrointestinal stromal tumors (GISTs) are caused by mutations in the KIT and PDGFRA genes. Avapritinib (BLU-285) is a targeted selective inhibitor for mutated KIT and PDGFRA receptors that can be used to treat these tumors. However, there are
Externí odkaz:
https://doaj.org/article/8a1383d23f0b4eabbd602b9ab5892fd4
Autor:
Maria Poley, Gal Chen, Noga Sharf-Pauker, Aviram Avital, Maya Kaduri, Mor Sela, Patricia Mora Raimundo, Lilach Koren, Sivan Arber, Egor Egorov, Janna Shainsky, Jeny Shklover, Avi Schroeder
Publikováno v:
Advanced NanoBiomed Research, Vol 2, Iss 12, Pp n/a-n/a (2022)
Males and females respond differently to medications due to physiologic, metabolic, and genetic factors. At times, sex‐related differences cannot be mitigated by dose adjustment to body mass, and are evident from the tissue level to the single cell
Externí odkaz:
https://doaj.org/article/f2cbb73ba8b34bc5ad30636da92e7fe7
Autor:
Zvi Yaari, Dana da Silva, Assaf Zinger, Evgeniya Goldman, Ashima Kajal, Rafi Tshuva, Efrat Barak, Nitsan Dahan, Dov Hershkovitz, Mor Goldfeder, Janna Shainsky Roitman, Avi Schroeder
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Determining the most effective treatment for each cancer patient is a key challenge in cancer therapy. In this article, the authors show, in a mouse model of breast cancer, that DNA barcoded nanoparticles can be used for pre-screening the efficacy of
Externí odkaz:
https://doaj.org/article/180b7ed375a34db78cbeed4472757033
Autor:
Nitzan Krinsky, Maya Kaduri, Janna Shainsky-Roitman, Mor Goldfeder, Eran Ivanir, Itai Benhar, Yuval Shoham, Avi Schroeder
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165137 (2016)
Cell-free protein synthesis (CFPS) systems are important laboratory tools that are used for various synthetic biology applications. Here, we present a simple and inexpensive laboratory-scale method for preparing a CFPS system from E. coli. The proced
Externí odkaz:
https://doaj.org/article/530d3764cd534f0fa66f1de827966de7
Autor:
Nitzan Krinsky, Sofia Sizikov, Sivan Nissim, Adi Dror, Anna Sas, Hodaya Prinz, Ester Pri-Or, Shay Perek, Ayelet Raz-Pasteur, Izabella Lejbkowicz, Sivan Ida Cohen-Matsliah, Ronit Almog, Nikanor Chen, Ramzi Kurd, Amir Jarjou'i, Ariel Rokach, Eli Ben-Chetrit, Avi Schroeder, Aleah F. Caulin, Christian Con Yost, Joshua D. Schiffman, Mor Goldfeder, Kimberly Martinod
Publikováno v:
Journal of Thrombosis and Haemostasis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b99e3372e9d728cfede445deef35943
https://doi.org/10.1016/j.jtha.2023.02.033
https://doi.org/10.1016/j.jtha.2023.02.033
Publikováno v:
International journal of molecular sciences. 24(1)
Isoamylase (ISA) is a debranching enzyme found in many plants, which hydrolyzes (1-6)-α-D glucosidic linkages in starch, amylopectin, and β-dextrins, and is thought to be responsible for starch granule formation (ISA1 and ISA2) and degradation (ISA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::76c3476cce3df30b84bedb8933f8c108
https://pubmed.ncbi.nlm.nih.gov/36613634
https://pubmed.ncbi.nlm.nih.gov/36613634
Autor:
Gal Chen, Rotem Levin, Shira Landau, Maya Kaduri, Omer Adir, Iris Ianovici, Nitzan Krinsky, Ofri Doppelt-Flikshtain, Jeny Shklover, Janna Shainsky-Roitman, Shulamit Levenberg, Avi Schroeder
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Progress in bottom-up synthetic biology has stimulated the development of synthetic cells (SCs), autonomous protein-manufacturing particles, as dynamic biomimetics for replacing diseased natural cells and addressing medical needs. Here, we report tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11a4d339dbe91ce5d96986382b1f2fef
https://doi.org/10.1073/pnas.2207525119
https://doi.org/10.1073/pnas.2207525119