Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Avi Rimler"'
Autor:
Ori Wand, Anna Breslavsky, Amir Bar-Shai, Chezy Levy, Shlomo Maayan, Avi Rimler, Moatasem Zwahra, Keren Cohen-Hagai, Alma Harish, Nadav Zacks, Natalya Bilenko
Publikováno v:
Vaccine. 41:871-874
A third dose of the BNT162b2 SARS-CoV-2 vaccine leads to a significant increase in antibody levels, however, concerns regarding the long-term persistence of this response exist. We assessed the humoral response for one year following vaccination.A pr
Publikováno v:
Journal of Molecular Neuroscience. 31:1-12
Nuclear localization of androgen receptors (ARs) is essential for their activity. Melatonin induces AR nuclear exclusion via increase in cGMP, calcium, and protein kinase C (PKC) activation, presumably through G-protein(s). The effects of regulators
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 81:77-84
Androgen receptors (AR) play a crucial role in androgen-mediated processes and prostate cancer progression. The pineal hormone melatonin attenuates the androgen-dependent growth of benign and cancer prostate epithelial cells in vitro and may reverse
Publikováno v:
The Prostate. 40:211-217
Background Epithelial cells from the human benign prostate express melatonin receptors which effect transient suppression of DNA synthesis and sustained attenuation of growth. The role of transforming growth factor-beta1 (TGFbeta1), which is produced
Publikováno v:
Journal of pineal research. 40(2)
Regulators of G protein signaling (RGS) are proteins that bind specifically to activated Galpha subunits of heterotrimeric G proteins to terminate signaling by both Galpha and Gbetagamma subunits. Signal-induced RGS redistribution may affect their ac
Publikováno v:
Cellular and molecular life sciences : CMLS. 58(14)
The intracellular signaling pathways mediating the nuclear exclusion of the androgen receptor (AR) by melatonin were evaluated in PC3 cells stably transfected with the AR. The melatonin-induced nuclear exclusion of the AR by melatonin (100 nM, 3 h) w
Autor:
Zippora Lupowitz, Zoran Culig, Georg Bartsch, Nava Zisapel, Galit Levy-Rimler, Avi Rimler, Helmut Klocker, Haim Matzkin
Publikováno v:
The Prostate. 49(2)
Background The androgen receptor (AR) promotes growth and functionality of androgen sensitive benign and cancer tissues. The pineal hormone melatonin is an androgen protagonist in vivo and in vitro. The interference of melatonin in the AR cascade was
Publikováno v:
Neuro endocrinology letters. 23
The pineal hormone melatonin inhibits the growth of benign human prostate epithelial cells and the androgen-dependent prostate cancer LNCaP cells. In the androgen-nonresponsive prostate carcinoma PC3 cells melatonin inhibits cell growth only at high
Publikováno v:
European Urology Supplements. 1:52