Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Avi Chakrabartty"'
Autor:
Avi Chakrabartty
Publikováno v:
Pharmaceuticals, Vol 17, Iss 9, p 1225 (2024)
The disease of transthyretin (TTR) amyloidosis (ATTR) has been known since the 1960s, and during the past 60 or so years, there has been a sustained period of steady discoveries that have led to the current model of ATTR pathogenesis. More recent res
Externí odkaz:
https://doaj.org/article/e71e0c31f22f4dd09cdecf9ea4c32fd1
Autor:
Anatoly Malevanets, P. Andrew Chong, D. Flemming Hansen, Paul Rizk, Yulong Sun, Hong Lin, Ranjith Muhandiram, Avi Chakrabartty, Lewis E. Kay, Julie D. Forman-Kay, Shoshana J. Wodak
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Misofolding of mammalian prion proteins (PrP) is believed to be the cause of a group of rare and fatal neurodegenerative diseases. Despite intense scrutiny however, the mechanism of the misfolding reaction remains unclear. We perform nuclear
Externí odkaz:
https://doaj.org/article/2cc9aa29f07a4e49a4b2965ad45484b5
Autor:
Hansen Wang, Lisa D Muiznieks, Punam Ghosh, Declan Williams, Michael Solarski, Andrew Fang, Alejandro Ruiz-Riquelme, Régis Pomès, Joel C Watts, Avi Chakrabartty, Holger Wille, Simon Sharpe, Gerold Schmitt-Ulms
Publikováno v:
eLife, Vol 6 (2017)
The amyloid β peptide (Aβ) is a key player in the etiology of Alzheimer disease (AD), yet a systematic investigation of its molecular interactions has not been reported. Here we identified by quantitative mass spectrometry proteins in human brain e
Externí odkaz:
https://doaj.org/article/335a92b94e58463380f20574bebf20a3
Autor:
Akter, M H Rahman, Mas Khan, Ehteshamul Islam, Mudasir Hassan, Islam, Avi Chakrabartty, M Giasuddin
Publikováno v:
SAARC Journal of Agriculture. 19:201-210
Foot and mouth disease (FMD) is a devastating viral disease and endemic in nature in Bangladesh that causes huge economical losses. The present research work was aimed to determine the prevalence of FMD outbreaks and molecular detection of FMDV serot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c7b6e92f3f8bcae64f102465ea27409
https://doi.org/10.3329/sja.v19i1.54790
https://doi.org/10.3329/sja.v19i1.54790
Autor:
Daniel Durocher, Leo C. K. Wan, Neroshan Thevakumaran, Frank Sicheri, Monica C. Pillon, Avi Chakrabartty, Yulong Sun, Alba Guarné, Igor Kurinov
Publikováno v:
Nucleic Acids Research
KEOPS is an ancient protein complex required for the biosynthesis of N6-threonylcarbamoyladenosine (t(6)A), a universally conserved tRNA modification found on all ANN-codon recognizing tRNAs. KEOPS consist minimally of four essential subunits, namely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001986c1d9c90e17c445508e94ae1821
https://doi.org/10.1093/nar/gkw542
https://doi.org/10.1093/nar/gkw542
Autor:
Nijjar Tarlochan S, Stephen J. Tam, Bradley Hammerson, Avi Chakrabartty, Jose R. Tapia, Robin Barbour, Ronald Torres, Gene G. Kinney, Ken Flanagan, Wagner Zago, Salmans Joshua Reginald, Jeffrey N. Higaki, Kevin C. Hadley, Natalie J. Galant
Publikováno v:
Amyloid
Introduction: Transthyretin amyloidosis (ATTR amyloidosis) is caused by the misfolding and deposition of the transthyretin (TTR) protein and results in progressive multi-organ dysfunction. TTR epitopes exposed by dissociation and misfolding are targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53abd6c8fd0d213c6e3ad3032fcb1ab3
https://doi.org/10.3109/13506129.2016.1148025
https://doi.org/10.3109/13506129.2016.1148025
Autor:
Michael Solarski, Régis Pomès, Gerold Schmitt-Ulms, Declan Williams, Simon Sharpe, Hansen Wang, Andrew Fang, Lisa D. Muiznieks, Holger Wille, Alejandro Ruiz-Riquelme, Avi Chakrabartty, Punam Ghosh, Joel C. Watts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84d9875d7a45c4bc76c0d82475c90943
https://doi.org/10.7554/elife.28401.022
https://doi.org/10.7554/elife.28401.022
Autor:
Simon Sharpe, Holger Wille, Hansen Wang, Lisa D. Muiznieks, Michael Solarski, Declan Williams, Gerold Schmitt-Ulms, Punam Ghosh, Alejandro Ruiz-Riquelme, Joel C. Watts, Avi Chakrabartty, Andrew Fang, Régis Pomès
Publikováno v:
eLife, Vol 6 (2017)
eLife
eLife
The amyloid β peptide (Aβ) is a key player in the etiology of Alzheimer disease (AD), yet a systematic investigation of its molecular interactions has not been reported. Here we identified by quantitative mass spectrometry proteins in human brain e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad2fb5f9649ff6034c5dcf5b70b33d4a
https://elifesciences.org/articles/28401
https://elifesciences.org/articles/28401
Autor:
Ranjith Muhandiram, P. Andrew Chong, Hong Lin, Avi Chakrabartty, Paul Rizk, Julie D. Forman-Kay, Lewis E. Kay, D. Flemming Hansen, Yulong Sun, Shoshana J. Wodak, Anatoly Malevanets
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports
Scientific Reports
Misofolding of mammalian prion proteins (PrP) is believed to be the cause of a group of rare and fatal neurodegenerative diseases. Despite intense scrutiny however, the mechanism of the misfolding reaction remains unclear. We perform nuclear Magnetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b67068ba1b1754b8f2eb2a39ae53abe8
https://doi.org/10.1038/s41598-017-00954-7
https://doi.org/10.1038/s41598-017-00954-7
Publikováno v:
Biochemistry. 53:5885-5894
TAR DNA binding protein of 43 kDa (TDP-43) has been implicated in the pathogenesis of a broad range of neurodegenerative diseases termed TDP-43 proteinopathies, which encompass a spectrum of diseases ranging from amyotrophic lateral sclerosis to fron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed183a7d3a0cb14ccb50acf4c8b284e3
https://doi.org/10.1021/bi500617x
https://doi.org/10.1021/bi500617x