Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Avi Avramoff"'
Publikováno v:
Journal of Controlled Release. 160:401-406
Objective Preparation and characterization of an oral pro-dispersion liposphere formulation for cyclosporin, a water insoluble drug with limited bioavailability. Methods Pro-dispersion formulation consisted of a solid fat, dispersing agents and amphi
Publikováno v:
Journal of Applied Polymer Science. 126:E197-E203
The aim of the present study was to develop a once-daily, delayed controlled release formulation for diltiazem. Developed formulation consists of two coated tablets inserted into a capsule; the first tablet is intended to produce a fast release profi
Publikováno v:
Journal of Clinical Periodontology
Local delivery of antimicrobial agents as an adjunctive tool in the treatment of periodontal disease has been in use for over three decades now (Lindhe et al. 1979). An array of agents has been tested with varying degree of success. These are general
Autor:
Abraham J. Domb, Avi Avramoff
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 48:250-258
Objective The aim of the present study was to evaluate the in-vitro dissolution and in-vivo pharmacokinetic profile of a novel two-phase modified-release formulation for diltiazem hydrochloride, as a water-soluble drug. Materials and methods The deli
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 45:126-132
Objective: A study was conducted to establish the bioequivalence between a newly developed cyclosporin A (CsA) oral formulation, Deximune® soft-gelatin capsules (Dexcel Ltd.) and Sandimmune Neoral® (Novartis Inc.). Materials and methods: The clinic
Publikováno v:
International journal of pharmaceutics. 437(1-2)
Cyclosporin A (CsA) is a widely used anti-inflammatory agent for the management of dry eye disease, and is available commercially as ophthalmic emulsion formulation (RESTASIS(®)). For increasing efficacy, and for reducing local toxicity including ir
Publikováno v:
International Journal of Pharmaceutics. 111:197-202
We have recently discovered that peptides are absorbed biologically intact from the rat uterus. The purpose of this investigation was to assess whether EPO, a large polypeptide hormone (34.5 kDa), can be absorbed from the uterus into the systemic blo
Publikováno v:
Pharmaceutical Research. 10:828-833
High molecular weight drugs in general, and peptides in particular, are usually delivered by parenteral route because they are poorly absorbed or degraded in the gastrointestinal tract. To optimize therapy, it is desirable to search for nonparenteral
Publikováno v:
International journal of clinical pharmacology and therapeutics. 46(4)
Objective: Deximune® soft-gelatin capsules (Dexcel Ltd., Hadera, Israel), the test preparation and Sandimmun Neoral® (Novartis Inc., Basel, Switzerland), the reference preparation, are two cyclosporine (CyA) formulations widely used after stem cell