Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Avi, Raveh"'
Autor:
Dana Laor, Dorin Sade, Shira Shaham-Niv, Dor Zaguri, Myra Gartner, Vasantha Basavalingappa, Avi Raveh, Edward Pichinuk, Hamutal Engel, Keita Iwasaki, Tatsuyuki Yamamoto, Hemanth Noothalapati, Ehud Gazit
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Small molecule metabolites like phenylalanine can form amyloid-like structures but so far this has only been demonstrated in vitro. Here the authors generate a yeast in vivo model of adenine self-assembly and characterize the adenine assemblies in ce
Externí odkaz:
https://doaj.org/article/378a668465b54f94a2144b2dc009b093
Autor:
Shira, Burg, Shir, Shapiro, Asher, Peretz, Elvira, Haimov, Boris, Redko, Adva, Yeheskel, Luba, Simhaev, Hamutal, Engel, Avi, Raveh, Ariel, Ben-Bassat, Michael, Murninkas, Rotem, Polak, Yoni, Haitin, Yoram, Etzion, Bernard, Attali
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(34)
The Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7a35f366bf4a19cd34cad020a7885ec1
https://pubmed.ncbi.nlm.nih.gov/35969786
https://pubmed.ncbi.nlm.nih.gov/35969786
Autor:
Shira Burg, Shir Shapiro, Asher Peretz, Elvira Haimov, Boris Redko, Adva Yeheskel, Luba Simhaev, Hamutal Engel, Avi Raveh, Ariel Ben-Bassat, Michael Murninkas, Rotem Polak, Yoni Haitin, Yoram Etzion, Bernard Attali
Publikováno v:
Proceedings of the National Academy of Sciences. 119
The Ca 2+ -activated SK4 K + channel is gated by Ca 2+ –calmodulin (CaM) and is expressed in immune cells, brain, and heart. A cryoelectron microscopy (cryo-EM) structure of the human SK4 K + channel recently revealed four CaM molecules per channel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17e08b100bc668ba06b4337b52420412
https://doi.org/10.1073/pnas.2202926119
https://doi.org/10.1073/pnas.2202926119
Autor:
Hamutal Engel, Fabien Gosselet, Elad Arad, Guru KrishnaKumar Viswanathan, Itzik Cooper, Dana Shwartz, Chen Shemesh, Avi Raveh, Yelena Losev, Raz Jelinek, Daniel L. Segal, Edward Pichinuk, Ehud Gazit
Publikováno v:
Cellular and Molecular Life Sciences
Cellular and Molecular Life Sciences, Springer Verlag, 2019, ⟨10.1007/s00018-019-03312-0⟩
Cellular and Molecular Life Sciences, Springer Verlag, 2019, ⟨10.1007/s00018-019-03312-0⟩
International audience; Neurofibrillary tangles of the Tau protein and plaques of the amyloid β peptide are hallmarks of Alzheimer's disease (AD), which is characterized by the conversion of monomeric proteins/peptides into misfolded β-sheet rich f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd0427d33b2371643803bc263498a6f9
https://doi.org/10.1007/s00018-019-03312-0
https://doi.org/10.1007/s00018-019-03312-0
Supramolecular architecture formation by the self-assembly of proteins and nucleic acids is well studied. Yet, the spontaneous organization of oligosaccharides, the most common polymers in nature, is less explored. Here, using inulin as a model, we i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b5124badc88d8ec69db112176ee7d9d
https://doi.org/10.1101/2021.07.13.451276
https://doi.org/10.1101/2021.07.13.451276
Autor:
Avi Raveh, Phillip C Delekta, Craig J Dobry, Weiping Peng, Pamela J Schultz, Pennelope K Blakely, Andrew W Tai, Teatulohi Matainaho, David N Irani, David H Sherman, David J Miller
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82318 (2013)
Natural products provide a vast array of chemical structures to explore in the discovery of new medicines. Although secondary metabolites produced by microbes have been developed to treat a variety of diseases, including bacterial and fungal infectio
Externí odkaz:
https://doaj.org/article/f2ab84591b104529920e80c118497a91
Autor:
Dorin Sade, Hemanth Noothalapati, Avi Raveh, Edward Pichinuk, Keita Iwasaki, Tatsuyuki Yamamoto, Ehud Gazit, Vasantha Basavalingappa, Myra Gartner, Hamutal Engel, Dana Laor, Dor Zaguri, Shira Shaham-Niv
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
The extension of the amyloid hypothesis to include non-protein metabolite assemblies invokes a paradigm for the pathology of inborn error of metabolism disorders. However, a direct demonstration of the assembly of metabolite amyloid-like structures h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f95d736b5d754243688c4a557c638b
https://doi.org/10.1038/s41467-018-07966-5
https://doi.org/10.1038/s41467-018-07966-5
Autor:
Avi Raveh, Teatulohi Matainaho, Giselle Tamayo-Castillo, George E. Chlipala, Ryan MacArthur, Shugeng Cao, Patricia Dranchak, Richard T. Eastman, Ken Chih-Chien Cheng, David H. Sherman, Pamela J. Schultz, Jon Clardy, James Inglese, Jing Yuan, Rajarshi Guha, Matthew T. Okoneski, Xin-zhuan Su
Publikováno v:
Journal of Natural Products, Vol.78, Núm. 10, 2015
Kérwá
Universidad de Costa Rica
instacron:UCR
Kérwá
Universidad de Costa Rica
instacron:UCR
Methods to identify the bioactive diversity within natural product extracts (NPEs) continue to evolve. NPEs constitute complex mixtures of chemical substances varying in structure, composition, and abundance. NPEs can therefore be challenging to eval
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f3cd487bbec1f92fc6630a4a00b7f14
https://doi.org/10.1021/acs.jnatprod.5b00489
https://doi.org/10.1021/acs.jnatprod.5b00489
Autor:
Avi Raveh, Martha J. Larsen, David H. Sherman, Giselle Tamayo-Castillo, David J. Miller, Phillip C. Delekta, Pamela J. Schultz
Publikováno v:
Journal of Biomolecular Screening, 20(5), p. 673-680.
Kérwá
Universidad de Costa Rica
instacron:UCR
Kérwá
Universidad de Costa Rica
instacron:UCR
Alphaviruses are a prominent class of reemergent pathogens due to their globally expanding ranges, potential for lethality, and possible use as bioweapons. The absence of effective treatments for alphaviruses highlights the need for innovative strate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22e7717d8d868c3d2d78df75e1f1595b
https://doi.org/10.1177/1087057114564868
https://doi.org/10.1177/1087057114564868
Autor:
Ehud Gazit, Hamutal Engel, Daniel L. Segal, Edward Pichinuk, Yelena Losev, V. Guru KrishnaKumar, Avi Raveh, Esraa Haj
Publikováno v:
Biochimica et biophysica acta. General subjects. 1862(7)
Background Alzheimer's disease (AD) is the most common neurodegenerative disorder which is characterized by the deposits of intra-cellular tau protein and extra-cellular amyloid-β (Aβ) peptides in the human brain. Understanding the mechanism of pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b45de6e704826a5cb9fea7e5230ebb08
https://pubmed.ncbi.nlm.nih.gov/29634991
https://pubmed.ncbi.nlm.nih.gov/29634991