Zobrazeno 1 - 10
of 216
pro vyhledávání: '"Avery, August"'
Autor:
Nisha Kannan, Annette Choi, Mariela A. Rivera De Jesus, Peter Male Wei, Julie Marie Sahler, Stephanie Marie Curley, Avery August, Matthew P. DeLisa, Gary R. Whittaker, David Putnam
Publikováno v:
Vaccines, Vol 12, Iss 7, p 724 (2024)
Influenza is a highly contagious respiratory disease, resulting in an estimated 3 to 5 million cases of severe illness annually. While most influenza vaccines are administered parenterally via injection, one shortcoming is that they do not generate a
Externí odkaz:
https://doaj.org/article/b5f6cbbd4d6b420a901cd7c914038655
Autor:
Siqi Gao, Alan T. Tang, Min Wang, David W. Buchholz, Brian Imbiakha, Jisheng Yang, Xiaowen Chen, Peter Hewins, Patricia Mericko-Ishizuka, N. Adrian Leu, Stephanie Sterling, Avery August, Kellie A. Jurado, Edward E. Morrisey, Hector Aguilar-Carreno, Mark L. Kahn
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Endothelial damage and vascular pathology have been recognized as major features of COVID-19 since the beginning of the pandemic. Two main theories regarding how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) damages endothelial cells a
Externí odkaz:
https://doaj.org/article/e5d15a44eed14d9d8481a9fdb43d3196
Autor:
Duncan G. Ithinji, David W. Buchholz, Shahrzad Ezzatpour, I. Abrrey Monreal, Yu Cong, Julie Sahler, Amandip Singh Bangar, Brian Imbiakha, Viraj Upadhye, Janie Liang, Andrew Ma, Birgit Bradel-Tretheway, Benjamin Kaza, Yao Yu Yeo, Eun Jin Choi, Gunner P. Johnston, Louis Huzella, Erin Kollins, Saurabh Dixit, Shuiqing Yu, Elena Postnikova, Victoria Ortega, Avery August, Michael R. Holbrook, Hector C. Aguilar
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-14 (2022)
Abstract Experimental vaccines for the deadly zoonotic Nipah (NiV), Hendra (HeV), and Ebola (EBOV) viruses have focused on targeting individual viruses, although their geographical and bat reservoir host overlaps warrant creation of multivalent vacci
Externí odkaz:
https://doaj.org/article/de5f5906bdda428eae62711a3887d67e
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionRituximab (R), an anti-CD20 monoclonal antibody (mAb) and the world’s first approved antibody for oncology patients, was combined with the CHOP chemotherapy regimen and markedly improved the prognosis of all B- cell–derived lymphomas,
Externí odkaz:
https://doaj.org/article/95faa76ed0e9431ca6c313736573abbd
Autor:
Candice B. Limper, Narda Bondah, Daphne Zhu, Alanis N. Villanueva, Uchenna K. Chukwukere, Weishan Huang, Avery August
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
One of the most proliferative periods for T cells occurs during their development in the thymus. Increased DNA replication can result in increased DNA mutations in the nuclear genome, but also in mitochondrial genomes. A high frequency of mitochondri
Externí odkaz:
https://doaj.org/article/fb58b5a8002b476899fd01333a2a0fa6
Autor:
Jessica Elmore, Chavez Carter, Amie Redko, Nicholas Koylass, Amelia Bennett, Max Mead, Marinel Ocasio-Rivera, Weishan Huang, Ankur Singh, Avery August
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
The kinase Itk is normally required for differentiation of IL-17-producing CD4 T-helper (Th)17 cells however, Elmore, Carter et al. now report that Itk can be bypassed during Th17 differentiation in Saccharopolyspora rectivirgula induced hypersensiti
Externí odkaz:
https://doaj.org/article/f149f6e20ad24cd3b72863321fe8bbe9
Autor:
Alan T Tang, David W Buchholz, Katherine M Szigety, Brian Imbiakha, Siqi Gao, Maxwell Frankfurter, Min Wang, Jisheng Yang, Peter Hewins, Patricia Mericko-Ishizuka, N Adrian Leu, Stephanie Sterling, Isaac A Monreal, Julie Sahler, Avery August, Xuming Zhu, Kellie A Jurado, Mingang Xu, Edward E Morrisey, Sarah E Millar, Hector C Aguilar, Mark L Kahn
Publikováno v:
PLoS Biology, Vol 21, Iss 2, p e3001989 (2023)
Angiotensin-converting enzyme 2 (ACE2) is the cell-surface receptor for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). While its central role in Coronavirus Disease 2019 (COVID-19) pathogenesis is indisputable, there remains significan
Externí odkaz:
https://doaj.org/article/1b38b8dd914148c090723f094f8d38fc
Publikováno v:
Bio-Protocol, Vol 12, Iss 17 (2022)
Type 1 regulatory T (Tr1) cells are an immunoregulatory CD4+ Foxp3- IL-10high T cell subset with therapeutic potential for various inflammatory diseases. Retroviral (RV) transduction has been a valuable tool in defining the signaling pathways and tra
Externí odkaz:
https://doaj.org/article/6ffecf32f84442238e29c342c3c7e816
Autor:
Weiqian Chen, Weishan Huang, Youqiu Xue, Ye Chen, Wenbin Qian, Jilin Ma, Avery August, Julie Wang, Song Guo Zheng, Jin Lin
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
CD4+Foxp3+ regulatory T cells (Tregs) play a crucial role in preventing autoimmunity and inflammation. There are naturally-derived in the thymus (tTreg), generated extrathymically in the periphery (pTreg), and induced in vitro culture (iTreg) with di
Externí odkaz:
https://doaj.org/article/14a322d8a4be4f139e36807b250349db
Autor:
Mahinbanu Mammadli, Rebecca Harris, Liye Suo, Adriana May, Teresa Gentile, Adam T. Waickman, Alaji Bah, Avery August, Elmar Nurmemmedov, Mobin Karimi
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 12, Pp n/a-n/a (2021)
Abstract Regulatory T cells (Tregs) play an important role in controlling autoimmunity and limiting tissue damage and inflammation. IL2‐inducible T cell kinase (Itk) is part of the Tec family of tyrosine kinases and is a critical component of T cel
Externí odkaz:
https://doaj.org/article/4b2076bcc0cb4825ad858a8c9823abea