Link between 5-hydroxymethycytosine levels and TET enzymes transcription in human MS brain

Autor: Tagliatesta, S, Ciccarone, F, Aversano, V, Novara, L, Nocchia, D, Reale, A, Salvetti, M, Caiafa, P, Zampieri, M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3686::3fe2e984ab4025867453c2c8d3cf98e0
http://hdl.handle.net/11573/1211121

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Ageing affects subtelomeric DNA methylation in blood cells from a large European population enrolled in the MARK-AGE study

Autor: Michele Zampieri, Beatrix Grubeck-Loebenstein, Alexander Bürkle, Mikko Hurme, P. Eline Slagboom, Florence Debacq-Chainiaux, Olivier Toussaint, Maria A. Blasco, Tilman Grune, Claudio Franceschi, Ewa Sikora, Maria Giulia Bacalini, Antti Hervonen, Eugène H.J.M. Jansen, Stefano Tagliatesta, Valentina Aversano, Anna Reale, Martijn E.T. Dollé, Miriam Capri, Marco Malavolta, Maria Moreno-Villanueva, Efstathios S. Gonos, Christiane Schön, Nicolle Breusing, Fabio Ciccarone, Jürgen Bernhardt, Paola Caiafa

Publikováno v: Geroscience, 43(3), 1283-1302. SPRINGER
GeroScience
Bacalini, M G, Reale, A, Malavolta, M, Ciccarone, F, Moreno-Villanueva, M, Dollé, M E T, Jansen, E, Grune, T, Gonos, E S, Schön, C, Bernhardt, J, Grubeck-Loebenstein, B, Sikora, E, Toussaint, O, Debacq-Chainiaux, F, Capri, M, Hervonen, A, Hurme, M, Slagboom, P E, Breusing, N, Aversano, V, Tagliatesta, S, Franceschi, C, Blasco, M A, Bürkle, A, Caiafa, P & Zampieri, M 2021, ' Ageing affects subtelomeric DNA methylation in blood cells from a large European population enrolled in the MARK-AGE study ', GeroScience, vol. 43, no. 3, pp. 1283-1302 . https://doi.org/10.1007/s11357-021-00347-9

Ageing leaves characteristic traces in the DNA methylation make-up of the genome. However, the importance of DNA methylation in ageing remains unclear. The study of subtelomeric regions could give promising insights into this issue. Previously report

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74a7e6d18327fc45d8ab380f1b4695cf
http://hdl.handle.net/10029/624923