Tissue-specific isoforms of the single C. elegans Ryanodine receptor gene unc-68 control specific functions.

Autor: Filipe Marques, Saurabh Thapliyal, Avelino Javer, Priyanka Shrestha, André E X Brown, Dominique A Glauser

Publikováno v: PLoS Genetics, Vol 16, Iss 10, p e1009102 (2020)

Ryanodine receptors (RyR) are essential regulators of cellular calcium homeostasis and signaling. Vertebrate genomes contain multiple RyR gene isoforms, expressed in different tissues and executing different functions. In contrast, invertebrate genom

Externí odkaz: https://doaj.org/article/d05b23d9ef8440bcbd92d02c358da321

Machine Learning for Determining Lateral Flow Device Results in Asymptomatic Population: A Diagnostic Accuracy Study

Autor: Paul Lewis-Borman, Lennard Lee, Benjamin Irving, Avelino Javer, Camila C. S. Caiado, Neeraj Lal, Nishali Patel, Elaine Leung, Helen Robbins, Robert Banathy, Bram Van Meurs, Piotr Chudzik, Andrew D Beggs, Lionel Tarassenko, Celina Whalley, Anna Dijkstra, Mark Branigan, Tom Fowler, Paria Yousefi

Publikováno v: SSRN Electronic Journal.

Introduction: Rapid antigen tests, in the form of lateral flow devices (LFD) allow testing of a large population for SARS-CoV-2 rapidly either on an asymptomatic or symptomatic basis and have been demonstrated to reduce transmission when used correct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a01fe1c35833f94fc6f3a994659f5f44
https://doi.org/10.2139/ssrn.3861638

Single-Molecule Localization Microscopy Reconstruction Using Noise2Noise for Super-Resolution Imaging of Actin Filaments

Autor: Joël Lefebvre, Bohdan Lewkow, Avelino Javer, Edward S. Allgeyer, Jens Rittscher, Daniel St Johnston, George Sirinakis, Mariia Dmitrieva

Publikováno v: ISBI

Single-molecule localization microscopy (SMLM) is a super-resolution imaging technique developed to image structures smaller than the diffraction limit. This modality results in sparse and non-uniform sets of localized blinks that need to be reconstr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea57e80a91c13b770c53460807eb8f1e
https://doi.org/10.1109/isbi45749.2020.9098713

Shared behavioral mechanisms underlie C. elegans aggregation and swarming

Autor: Linus J. Schumacher, Robert G. Endres, André Ex Brown, Siyu Serena Ding, Avelino Javer

Publikováno v: eLife, Vol 8 (2019)
Ding, S S, Schumacher, L J, Javer, A E, Endres, R G & Brown, A E 2019, ' Shared behavioral mechanisms underlie C. elegans aggregation and swarming ', eLIFE, vol. 8, e43318 . https://doi.org/10.7554/eLife.43318
eLife

In complex biological systems, simple individual-level behavioral rules can give rise to emergent group-level behavior. While collective behavior has been well studied in cells and larger organisms, the mesoscopic scale is less understood, as it is u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce4faf820f86069c5150e3d2dfe5f990
https://elifesciences.org/articles/43318

Semantic Filtering Through Deep Source Separation on Microscopy Images

Autor: Jens Rittscher, Avelino Javer

Publikováno v: Machine Learning in Medical Imaging ISBN: 9783030326913
MLMI@MICCAI

By their very nature microscopy images of cells and tissues consist of a limited number of object types or components. In contrast to most natural scenes, the composition is known a priori. Decomposing biological images into semantically meaningful o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e064f3110a5abb820583c4c976b9289
https://doi.org/10.1007/978-3-030-32692-0_57