Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Aveline Filliol"'
Autor:
Xiaobo Wang, Mark R. Sommerfeld, Kerstin Jahn‐Hofmann, Bishuang Cai, Aveline Filliol, Helen E. Remotti, Robert F. Schwabe, Aimo Kannt, Ira Tabas
Publikováno v:
Hepatology Communications, Vol 3, Iss 9, Pp 1221-1234 (2019)
Nonalcoholic steatohepatitis (NASH) is emerging as a major public health issue and is associated with significant liver‐related morbidity and mortality. At present, there are no approved drug therapies for NASH. The transcriptional coactivator with
Externí odkaz:
https://doaj.org/article/1e86ca922c85434d9c6ee005837b7f83
Autor:
Aveline Filliol, Muhammad Farooq, Claire Piquet-Pellorce, Valentine Genet, Marie-Thérèse Dimanche-Boitrel, Peter Vandenabeele, Mathieu J. M. Bertrand, Michel Samson, Jacques Le Seyec
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Hepatocyte death is a central event during liver disease progression, in which immune cells play key roles by activating members of the Tumor Necrosis Factor Receptor Superfamily (TNFRSF), including TNFR1 (TNFRSF1A), Fas (TNFRSF6) and TRAIL-
Externí odkaz:
https://doaj.org/article/5a69f5dded0846c29b4a7635d8cd5204
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 3, Pp 555-556 (2020)
Externí odkaz:
https://doaj.org/article/9bb58a4192c04ecf818bd064caffc327
Autor:
Yoshinobu Saito, Dingzi Yin, Naoto Kubota, Xiaobo Wang, Aveline Filliol, Helen Remotti, Ajay Nair, Ladan Fazlollahi, Yujin Hoshida, Ira Tabas, Kirk J. Wangensteen, Robert F. Schwabe
Publikováno v:
Gastroenterology. 164:1279-1292
Autor:
Aveline, Filliol, Robert F, Schwabe
Publikováno v:
Nature metabolism. 4(10)
Autor:
Jay H. Lefkowitch, Samuel F. Bakhoum, George A. Alba, Denis Schapiro, Yaron Bram, Patricia Ho, Ajay Nair, Anjali Saqi, Yiping Wang, Robert E. Schwartz, Daniel T. Montoro, Armando Del Portillo, Jianwen Que, Alain C. Borczuk, Robert F. Schwabe, Sean W. Chen, André F. Rendeiro, Johannes C. Melms, Somnath Tagore, Hanina Hibshoosh, Adrienne M. Luoma, Adam E. Kornberg, Amit Dipak Amin, Mariano G. Clausi, Niroshana Anandasabapathy, Chris J. Frangieh, Stephen M. Lagana, Olivier Elemento, Yinshan Fang, Huachao Huang, Igor Katsyv, Mayte Suárez-Fariñas, Xinzheng V. Guo, Benjamin Izar, Emily J. Tsai, Charles C. Marboe, Mathieu F. Bakhoum, Aveline Filliol, Glen S. Markowitz, Hiranmayi Ravichandran, Arnold Han, Emmanuel Zorn, Meri Rogava, Jana Biermann
Publikováno v:
Nature. 595:114-119
Respiratory failure is the leading cause of death in patients with severe SARS-CoV-2 infection1,2, but the host response at the lung tissue level is poorly understood. Here we performed single-nucleus RNA sequencing of about 116,000 nuclei from the l
Autor:
Hua Su, Fei Yang, Rao Fu, Brittney Trinh, Nina Sun, Junlai Liu, Avi Kumar, Jacopo Baglieri, Jeremy Siruno, Michelle Le, Yuhan Li, Stephen Dozier, Ajay Nair, Aveline Filliol, Nachanok Sinchai, Sara Brin Rosenthal, Jennifer Santini, Christian M. Metallo, Anthony Molina, Robert F. Schwabe, Andrew M. Lowy, David Brenner, Beicheng Sun, Michael Karin
Publikováno v:
Nature. 615:E24-E24
Autor:
Ingmar Mederacke, Aveline Filliol, Silvia Affo, Ajay Nair, Celine Hernandez, Qiuyan Sun, Florian Hamberger, Francesco Brundu, Yu Chen, Aashreya Ravichandra, Peter Huebener, Helena Anke, Hongxue Shi, Raquel A. Martínez García de la Torre, James R. Smith, Neil C. Henderson, Florian W. R. Vondran, Carla V. Rothlin, Heike Baehre, Ira Tabas, Pau Sancho-Bru, Robert F. Schwabe
Publikováno v:
Sci Transl Med
Fibrosis contributes to ~45% of deaths in western countries. In chronic liver disease, fibrosis is a major factor determining outcomes, but efficient antifibrotic therapies are lacking. Although platelet-derived growth factor and transforming growth
Autor:
Hua Su, Fei Yang, Rao Fu, Brittney Trinh, Nina Sun, Junlai Liu, Avi Kumar, Jacopo Baglieri, Jeremy Siruno, Stephen Dozier, Ajay Nair, Aveline Filliol, Sara Brin Rosenthal, Jennifer Santini, Christian M. Metallo, Anthony Molina, Robert F. Schwabe, Andrew M. Lowy, David Brenner, Beicheng Sun, Michael Karin
Pancreatic ductal adenocarcinoma (PDAC) is a highly desmoplastic, aggressive cancer that frequently progresses by liver metastasis1. Cancer-associated fibroblasts (CAF), extracellular matrix (ECM), and type I collagen (Col I) support2–5 or restrain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6611d760720caeddf2e5fae59f6fbb29
https://doi.org/10.1101/2022.04.02.486837
https://doi.org/10.1101/2022.04.02.486837
Publikováno v:
Nature
Cellular senescence is characterized by stable cell cycle arrest and a secretory program that modulates the tissue microenvironment1,2. Physiologically, senescence serves as a tumor suppressive mechanism that prevents the expansion of premalignant ce