Prevalence of Emergent Dolutegravir Resistance Mutations in People Living with HIV: A Rapid Scoping Review

Autor: Carolyn Chu, Kaiming Tao, Vinie Kouamou, Ava Avalos, Jake Scott, Philip M. Grant, Soo-Yon Rhee, Suzanne M. McCluskey, Michael R. Jordan, Rebecca L. Morgan, Robert W. Shafer

Publikováno v: Viruses, Vol 16, Iss 3, p 399 (2024)

Background: Dolutegravir (DTG) is a cornerstone of global antiretroviral (ARV) therapy (ART) due to its high efficacy and favorable tolerability. However, limited data exist regarding the risk of emergent integrase strand transfer inhibitor (INSTI) d

Externí odkaz: https://doaj.org/article/34d25c7a03884a529279d268af3e72b0

Five years after Treat All implementation: Botswana’s HIV response and future directions in the era of COVID-19

Autor: Keith Jefferis, Ava Avalos, Heston Phillips, Mpho Mmelesi, Dinah Ramaabya, Bornapate Nkomo, Charles Muthoga, Joseph N. Jarvis, Siphiwe Ratladi, Robert Selato, John Stover

Publikováno v: Southern African Journal of HIV Medicine, Vol 22, Iss 1, Pp e1-e11 (2021)

Background: As the relentless coronavirus disease-2019 (COVID-19) pandemic continues to spread across Africa, Botswana could face challenges maintaining the pathway towards control of its HIV epidemic. Objective: Utilising the Spectrum GOALS module

Externí odkaz: https://doaj.org/article/6d65c8eb644048febc7085b793d49f0e

Outcomes of the Botswana national HIV/AIDS treatment programme from 2002 to 2010: a longitudinal analysis

Autor: Dr. Mansour Farahani, MD, Anusha Vable, MHP, Refeletswe Lebelonyane, MD, Khumo Seipone, MD, Marina Anderson, MD, Ava Avalos, MD, Tim Chadborn, PhD, Hailu Tilahun, MSc, Danae Roumis, MSc, Themba Moeti, MBBS, Godfrey Musuka, DVM, Lesego Busang, MA, Tendani Gaolathe, MD, Kolaatamo C S Malefho, MD, Prof. Richard Marlink, MD

Publikováno v: The Lancet Global Health, Vol 2, Iss 1, Pp e44-e50 (2014)

Background: Short-term mortality rates among patients with HIV receiving antiretroviral therapy (ART) in sub-Saharan Africa are higher than those recorded in high-income countries, but systematic long-term comparisons have not been made because of th

Externí odkaz: https://doaj.org/article/9cfca1f3c8404436a0346dd8d84c84a5

Five years after Treat All implementation: Botswana's HIV response and future directions in the era of COVID-19

Autor: Ava Avalos, Charles Muthoga, Robert Selato, Siphiwe Ratladi, Mpho Mmelesi, Bornapate Nkomo, Dinah Ramaabya, Keith Jefferis, Heston Phillips, John Stover, Joseph N Jarvis

Publikováno v: Southern African Journal of HIV Medicine
Southern African Journal of HIV Medicine; Vol. 22 No. 1 (2021)
Southern African Journal of HIV Medicine, Vol 22, Iss 1, Pp e1-e11 (2021)

Background:As the relentless coronavirus disease-2019 (COVID-19) pandemic continues to spread across Africa, Botswana could face challenges maintaining the pathway towards control of its HIV epidemic. Objective:Utilising the Spectrum GOALS module (GO

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f91a3e2ae08a0261ddde872cfb1729
https://pubmed.ncbi.nlm.nih.gov/34853703

Four-class drug-resistant HIV-1 subtype C in a treatment experienced individual on dolutegravir-based antiretroviral therapy in Botswana

Autor: Ava Avalos, Christopher F. Rowley, Tendani Gaolatlhe, Mosepele Mosepele, Simani Gaseitsiwe, Sikhulile Moyo, Kaelo K Seatla, Dinah Ramaabya, Madisa Mine, Ishmael Kasvosve, Thabo Diphoko, Joseph N Jarvis

Publikováno v: AIDS

There are limited data on the effectiveness of dolutegravir (DTG)-based combination antiretroviral therapy (ART) in real-life settings in southern Africa where HIV-1 subtype C predominates. We report a patient infected with HIV-1 subtype C on DTG-bas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2412c18bae1b84037b966a09d787e8d5
https://doi.org/10.1097/qad.0000000000001920