Zobrazeno 1 - 10 of 95 pro vyhledávání: '"Auzzas L."'
1
NON-NATURAL MACROCYCLIC AMIDE HDAC6 INHIBITOR COMPOUNDS AND THEIR USES AS THERAPEUTIC AGENTS
Autor: Hanessian S., Auzzas L., Larsson A., Giannini G., Cabri W
The present invention relates to novel amide compounds of formula I, and their use as anti-tumoral and pro-apoptotic agents. The invention includes the use of such compounds in medicine, in relation to cancer disease as well as other diseases where a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4094::2d816665c7d19896b5d979aa84059739
http://hdl.handle.net/11585/757794
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2
omega-Alkoxy analogues of SAHA (vorinostat) as inhibitors of HDAC: A study of chain-length and stereochemical dependence
Autor: Hanessian S, Auzzas L, Giannini G, Marzi M, Cabri W, Barbarino M, Vesci L, Pisano C
A series of omega-alkoxy ethers were prepared with variation of the length of the aliphatic chain of suberoylanilide hydroxamic acid (SAHA, vorinostat). Eight carbon long chain analogues showed the best activity, among which several substituted benzy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4094::bfc4a3c5508f35a4e5673f153ff58804
http://hdl.handle.net/11585/756806
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5
Battling Cancer: A Fragment-Based Approach towards the Design of Multitargeted Ligands
Autor: Edvinsson, S., Larsson, A., Auzzas, L.
Publikováno v: 22nd Organikerdagarna, June 13-16, Uppsala (Sweden), Uppsala (Sweden), 2010
info:cnr-pdr/source/autori:Edvinsson, S.; Larsson, A.; Auzzas, L./congresso_nome:22nd Organikerdagarna, June 13-16, Uppsala (Sweden)/congresso_luogo:Uppsala (Sweden)/congresso_data:2010/anno:2010/pagina_da:/pagina_a:/intervallo_pagine
When treating cancer a combination of drugs targeting different disease-associated proteins or pathways is often needed to achieve the desired therapeutic effect. This project aims to develop a multitargeted ligand that can inhibit both X-linked inhi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::dc45d312348e4c161224b8bd62c94bee
https://publications.cnr.it/doc/104919
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6
Natural Fragments in the Design of Multitargeted Ligands
Autor: Larsson, A., Edvinsson, S., Auzzas, L.
Publikováno v: 22nd Organikerdagarna, June 13-16, Uppsala (Sweden), Uppsala (Sweden), June 13-16, 2010
info:cnr-pdr/source/autori:Larsson, A.; Edvinsson, S.; Auzzas, L./congresso_nome:22nd Organikerdagarna, June 13-16, Uppsala (Sweden)/congresso_luogo:Uppsala (Sweden)/congresso_data:June 13-16, 2010/anno:2010/pagina_da:/pagina_a:/intervallo_pagine
The inherent redundancy and robustness in many biological networks and pathways implies that the inhibition of a single target might fall short of producing the desired therapeutic effect. This situation is particularly emphasized in highly complex d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::677b7786eb489c52a0c031488f616885
http://www.cnr.it/prodotto/i/104920
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10
Sintesi di nuovi ligandi ibridi a base peptidica contenenti unità ciclopentaniche modulabili
Autor: Burreddu P., Rassu G., Auzzas L., Roggio A. M., Pinna L., Casiraghi G.
Publikováno v: Corso Estivo di Chimica Organica, Gargnano, 2006
info:cnr-pdr/source/autori:Burreddu P., Rassu G., Auzzas L., Roggio A. M., Pinna L., Casiraghi G./congresso_nome:Corso Estivo di Chimica Organica/congresso_luogo:Gargnano/congresso_data:2006/anno:2006/pagina_da:/pagina_a:/intervallo_pagine
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::df94b08c1a872995a83f06e82f536f71
https://publications.cnr.it/doc/77896
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