Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Autumn M Mcknite"'
Autor:
Maria Elisa Perez-Munoz, Autumn M McKnite, Evan G Williams, Johan Auwerx, Robert W Williams, Daniel A Peterson, Daniel C Ciobanu
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0224100 (2019)
The BXD family has become one of the preeminent genetic reference populations to understand the genetic and environmental control of phenotypic variation. Here we evaluate the responses to different levels of fat in the diet using both chow diet (CD,
Externí odkaz:
https://doaj.org/article/f3d9846ff7eb411caa71bf06f9310adf
Autor:
J. Porter Hunt, Samuel Dubinsky, Autumn M. McKnite, Kit Wun Kathy Cheung, Bianca D. vanGroen, Kathleen M. Giacomini, Saskia N. deWildt, Andrea N. Edginton, Kevin M. Watt
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 4, Pp 576-588 (2024)
Abstract Optimal treatment of infants with many renally cleared drugs must account for maturational differences in renal transporter (RT) activity. Pediatric physiologically‐based pharmacokinetic (PBPK) models may incorporate RT activity, but this
Externí odkaz:
https://doaj.org/article/7ff55455941a418ca3f7d873a040d3c9
Autor:
Autumn M McKnite, Maria Elisa Perez-Munoz, Lu Lu, Evan G Williams, Simon Brewer, Pénélope A Andreux, John W M Bastiaansen, Xusheng Wang, Stephen D Kachman, Johan Auwerx, Robert W Williams, Andrew K Benson, Daniel A Peterson, Daniel C Ciobanu
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39191 (2012)
The gastrointestinal tract harbors a complex and diverse microbiota that has an important role in host metabolism. Microbial diversity is influenced by a combination of environmental and host genetic factors and is associated with several polygenic d
Externí odkaz:
https://doaj.org/article/f51bd453bfbc412996f86192dfb734f5
Autor:
Samuel D.J. Dubinsky, PharmD, Kevin M. Watt, MD, PhD, Carina E. Imburgia, BSc, Autumn M. Mcknite, BSc, J. Porter Hunt, PhD, Cassandra Rice, PhD, Joseph E. Rower, PhD, DABCP, Andrea N. Edginton, PhD
Publikováno v:
Critical Care Explorations, Vol 5, Iss 12, p e1010 (2023)
OBJECTIVES:. Patients with sepsis are at significant risk for multiple organ dysfunction, including the lungs and kidneys. To manage the morbidity associated with kidney impairment, continuous renal replacement therapy (CRRT) may be required. The ext
Externí odkaz:
https://doaj.org/article/594b1e7149d64ebb8c4dc94f0d2a2b8c
Autor:
Rachel E. Hudson, Torri D. Metz, Robert M. Ward, Autumn M. McKnite, Elena Y. Enioutina, Catherine M. Sherwin, Kevin M. Watt, Kathleen M. Job
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Prescription drug use is prevalent during pregnancy, yet there is limited knowledge about maternal-fetal safety and efficacy of this drug use because pregnant individuals have historically been excluded from clinical trials. Underrepresentation has r
Externí odkaz:
https://doaj.org/article/56dfaa2dd7b64d4dac748c5a41cc25dc
Autor:
Kevin M. Watt, Danielle J Green, Autumn M Mcknite, Joseph E. Rower, Walter E Kelley, Christopher A. Reilly, Carina E Imburgia
Publikováno v:
ASAIO journal (American Society for Artificial Internal Organs : 1992). 68(9)
Patients with severe, COVID-related multi-organ failure often require extracorporeal life support (ECLS) such as extracorporeal membrane oxygenation (ECMO) or continuous renal replacement therapy (CRRT). An ECLS can alter drug exposure via multiple m
Autor:
Johan Auwerx, Daniel A. Peterson, Robert W. Williams, Autumn M. McKnite, Evan G. Williams, Maria Elisa Perez-Muñoz, Daniel C. Ciobanu
Publikováno v:
PLoS ONE
PLOS ONE
PLoS ONE, Vol 14, Iss 10, p e0224100 (2019)
PLOS ONE
PLoS ONE, Vol 14, Iss 10, p e0224100 (2019)
The BXD family has become one of the preeminent genetic reference populations to understand the genetic and environmental control of phenotypic variation. Here we evaluate the responses to different levels of fat in the diet using both chow diet (CD,
Autor:
Stephen D. Kachman, Judith A. Galeota, Max F. Rothschild, Theresa P. Johnson, Daniel C. Ciobanu, J. K. Qiu, Erin E. Jobman, T. W. Moural, Justin W Bundy, Sarah Y. Barnes, Rodger K. Johnson, Julie Kathleen Tart, Daniel A. Peterson, Autumn M. McKnite, Seth Harris
Publikováno v:
Animal Genetics. 45:205-214
Summary Porcine circovirus type 2 (PCV2) is the etiological agent of a group of associated diseases (PCVAD) that affect production efficiency and can lead to mortality. Using different crossbred lines of pigs, we analyzed host genetic variation of vi
Autor:
Stephen D. Kachman, Sarah Y. Barnes, Autumn M. McKnite, Emily H. Davis, Thomas E. Burkey, Daniel C. Ciobanu, Judith A. Galeota, Timonthy W. Moural, Taylor B. Engle, Justin W Bundy, Graham Plastow, Erin E. Jobman
Publikováno v:
BMC Veterinary Research
Background Porcine circovirus 2 is the primary agent responsible for inducing a group of associated diseases known as Porcine Circovirus Associated Diseases (PCVAD), which can have detrimental effects on production efficiency as well as causing signi
Autor:
Phillip S. Miller, Autumn M. McKnite, Justin W Bundy, Dorian J. Garrick, Max F. Rothschild, Jennifer R Wood, N. N. Ferdinand, Rodger K. Johnson, Julie Kathleen Tart, Matthew L Spangler, Stephen D. Kachman, Daniel C. Ciobanu
Publikováno v:
Animal genetics. 44(4)
Summary Traditional selection for sow reproductive longevity is ineffective due to low heritability and late expression of the trait. Incorporation of DNA markers into selection programs is potentially a more practical approach for improving sow life