Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Autumn Gaither-Davis"'
Autor:
Suet Kee Loo, Gabriel Sica, Xian Wang, Tingting Li, Luping Chen, Autumn Gaither-Davis, Yufei Huang, Timothy F. Burns, Laura P. Stabile, Shou-Jiang Gao
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Background Lung cancer, a leading global cause of cancer-related mortality, necessitates enhanced prognostic markers for improved treatment outcomes. We have previously shown a tumor suppressive role of cytosolic arginine sensor for mTORC1 s
Externí odkaz:
https://doaj.org/article/acd6b3c9b3c7486ca1dd6bfc35c3d602
Autor:
Madelyn Espinosa-Cotton, Elana J. Fertig, Laura P. Stabile, Autumn Gaither-Davis, Julie E. Bauman, Sandra Schmitz, Katherine N. Gibson-Corley, Yinwen Cheng, Isaac J. Jensen, Vladimir P. Badovinac, Douglas Laux, Andrean L. Simons
Publikováno v:
Biomarker Research, Vol 7, Iss 1, Pp 1-11 (2019)
Abstract Background The epidermal growth factor receptor (EGFR) monoclonal IgG1 antibody cetuximab is approved for first-line treatment of recurrent and metastatic (R/M) HNSCC as a part of the standard of care EXTREME regimen (platinum/5-fluorouracil
Externí odkaz:
https://doaj.org/article/7cb94e7905894534bb5933db154e06cd
Autor:
Laura P. Stabile, Vinod Kumar, Autumn Gaither-Davis, Eric H. Huang, Frank P. Vendetti, Princey Devadassan, Sanja Dacic, Riyue Bao, Richard A. Steinman, Timothy F. Burns, Christopher J. Bakkenist
Publikováno v:
JCI Insight, Vol 6, Iss 3 (2021)
Human lung adenocarcinoma (LUAD) in current or former smokers exhibits a high tumor mutational burden (TMB) and distinct mutational signatures. Syngeneic mouse models of clinically relevant smoking-related LUAD are lacking. We established and charact
Externí odkaz:
https://doaj.org/article/1954918282e2448aad0dedcd45e8477d
Autor:
David Sidransky, William Rom, William L. Bigbee, Autumn Gaither Davis, Jennifer R. Grandis, Jill M. Siegfried, Alissa Greenberg, Marianna Brait, Myriam Loyo, Mohammad O. Hoque, Kimberly Laskie Ostrow
Purpose: Aberrant promoter hypermethylation of tumor suppressor genes is a promising marker for lung cancer detection. We investigated the likelihood of detecting aberrant DNA methylation of tumor suppressor genes in plasma samples of patients with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a72708f65d5f00a0c010feb220d6d6f
https://doi.org/10.1158/1078-0432.c.6518413.v1
https://doi.org/10.1158/1078-0432.c.6518413.v1
Autor:
David Sidransky, William Rom, William L. Bigbee, Autumn Gaither Davis, Jennifer R. Grandis, Jill M. Siegfried, Alissa Greenberg, Marianna Brait, Myriam Loyo, Mohammad O. Hoque, Kimberly Laskie Ostrow
Supplementary Table S2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4acad8d6729a3046a69b737cbdf594dd
https://doi.org/10.1158/1078-0432.22441324
https://doi.org/10.1158/1078-0432.22441324
Autor:
Jill M. Siegfried, Adam C. Soloff, Autumn Gaither Davis, Amy A. Powers, Seth H. Eisenberg, Laura P. Stabile
Publikováno v:
Cancer Prevention Research. 15:A019-A019
Former smokers have an elevated risk of lung cancer and account for a large proportion of newly diagnosed lung cancer. Former smokers with airway dysplasia have received modest benefit in randomized chemoprevention trials, while active smokers have n
Autor:
Douglas Earl Laux, Sandra Schmitz, Laura P. Stabile, Isaac J. Jensen, Vladimir P. Badovinac, Elana J. Fertig, Julie E. Bauman, Madelyn Espinosa-Cotton, Yinwen Cheng, Andrean L. Simons, Autumn Gaither-Davis, Katherine N. Gibson-Corley
Publikováno v:
Biomarker Research, Vol 7, Iss 1, Pp 1-11 (2019)
Biomarker research, Vol. 7, p. 14 [1-11] (2019)
Biomarker Research
Biomarker research, Vol. 7, p. 14 [1-11] (2019)
Biomarker Research
Background The epidermal growth factor receptor (EGFR) monoclonal IgG1 antibody cetuximab is approved for first-line treatment of recurrent and metastatic (R/M) HNSCC as a part of the standard of care EXTREME regimen (platinum/5-fluorouracil/cetuxima
Autor:
Princey Devadassan, Laura P. Stabile, Timothy F. Burns, Sanja Dacic, Riyue Bao, Christopher J. Bakkenist, Eric H.-B. Huang, Richard A. Steinman, Vinod Kumar, Frank P. Vendetti, Autumn Gaither-Davis
Publikováno v:
JCI Insight
JCI Insight, Vol 6, Iss 3 (2021)
JCI Insight, Vol 6, Iss 3 (2021)
Human lung adenocarcinoma (LUAD) in current or former smokers exhibits a high tumor mutational burden (TMB) and distinct mutational signatures. Syngeneic mouse models of clinically relevant smoking-related LUAD are lacking. We established and charact
Autor:
James Ohr, Seungwon Kim, Laura P. Stabile, Julie E. Bauman, William E. Gooding, Robert L. Ferris, Jonas T. Johnson, Umamaheswar Duvvuri, John Winslow, Gerald J. Wallweber, Autumn Gaither-Davis, Adam C. Soloff, Jennifer R. Grandis
Publikováno v:
Cancers, Vol 12, Iss 1537, p 1537 (2020)
Cancers
Cancers, vol 12, iss 6
Volume 12
Issue 6
Cancers
Cancers, vol 12, iss 6
Volume 12
Issue 6
Cetuximab, an anti-EGFR monoclonal antibody (mAb), is approved for advanced head and neck squamous cell carcinoma (HNSCC) but benefits a minority. An established tumor-intrinsic resistance mechanism is cross-talk between the EGFR and hepatocyte growt
Autor:
Linda G. Griffith, Michael C. Gorry, Miles A. Miller, Nikola L. Vujanovic, Autumn Gaither-Davis, Marcia L. Moss, Lazar Vujanovic, Yan Lin, James G. Herman, Andrea Sobo-Vujanovic, Douglas A. Lauffenburger, Laura P. Stabile, Toshie Yoneyama
Publikováno v:
Journal of Cancer
Background: Increases in expression of ADAM10 and ADAM17 genes and proteins are inconsistently found in cancer lesions, and are not validated as clinically useful biomarkers. The enzyme-specific proteolytic activities, which are solely mediated by th