Zobrazeno 1 - 10
of 275
pro vyhledávání: '"Autosomal-dominant Alzheimer's disease"'
Autor:
Stephanie Langella, Kyra Bonta, Yinghua Chen, Yi Su, Daniel Vasquez, David Aguillon, Natalia Acosta-Baena, Ana Y. Baena, Gloria Garcia-Ospina, Margarita Giraldo-Chica, Victoria Tirado, Claudia Muñoz, Silvia Ríos-Romenets, Claudia Guzman-Martínez, Jeremy J. Pruzin, Valentina Ghisays, Joseph F. Arboleda-Velasquez, Kenneth S. Kosik, Pierre N. Tariot, Eric M. Reiman, Francisco Lopera, Yakeel T. Quiroz
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-9 (2024)
Abstract Background Apolipoprotein E (APOE) genotypes have been suggested to influence cognitive impairment and clinical onset in presenilin-1 (PSEN1) E280A carriers for autosomal dominant Alzheimer’s disease (ADAD). Less is known about their impac
Externí odkaz:
https://doaj.org/article/3234fbf9ef1a4a4bae611ce4cce7ba51
Autor:
María Carmona-Iragui, Antoinette O'Connor, Jorge Llibre-Guerra, Patrick Lao, Nicholas J. Ashton, Juan Fortea, Raquel Sánchez-Valle
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105327- (2024)
Summary: Autosomal dominant Alzheimer's disease (ADAD) and Down syndrome (DS) constitute genetic forms of Alzheimer's disease (AD). The study of these forms has been crucial in understanding the biomarker changes and disease progression, notably in a
Externí odkaz:
https://doaj.org/article/8547582ebab9497f8370b64b43339c2f
Autor:
Angélica Zuno‐Reyes, Karina Pérez‐Rubio, Martín Alonso Flores‐González, Ricardo Jauregui Torres, Sofía Dumois‐Petersen, Luis E. Figuera, John M. Ringman, Esmeralda Matute
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 3, Pp n/a-n/a (2024)
Abstract INTRODUCTION We aimed to determine the effect of years of schooling (YoS) and age on the Mexican adaptation of the Consortium to Establish a Registry for Alzheimer's Disease (CERAD‐MX) scores in preclinical carriers group (PCG) and non‐c
Externí odkaz:
https://doaj.org/article/47eb2ee19f614c938f98a53880703338
Autor:
Konstantinos Chiotis, Charlotte Johansson, Elena Rodriguez-Vieitez, Nicholas J. Ashton, Kaj Blennow, Henrik Zetterberg, Caroline Graff, Agneta Nordberg
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-14 (2023)
Abstract Background Plasma assays for the detection of Alzheimer’s disease neuropathological changes are receiving ever increasing interest. The concentration of plasma glial fibrillary acidic protein (GFAP) has been suggested as a potential marker
Externí odkaz:
https://doaj.org/article/5a23a9f0e9bb4a27a6b65948d57561d6
Autor:
Fran C. van Heusden, Anne M. van Nifterick, Bryan C. Souza, Arthur S. C. França, Ilse M. Nauta, Cornelis J. Stam, Philip Scheltens, August B. Smit, Alida A. Gouw, Ronald E. van Kesteren
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-21 (2023)
Abstract Background Studies in animal models of Alzheimer’s disease (AD) have provided valuable insights into the molecular and cellular processes underlying neuronal network dysfunction. Whether and how AD-related neurophysiological alterations tr
Externí odkaz:
https://doaj.org/article/f890c4d9a0874d4687c36487e129d99f
Autor:
Angélica Zuno-Reyes, Esmeralda Matute, Karin Ernstrom, Mellissa Withers, Yaneth Rodriguez-Agudelo, Rema Raman, John M. Ringman
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-10 (2022)
Abstract Background The enrollment into clinical trials of persons at risk for autosomal dominant Alzheimer’s disease (ADAD) in whom the onset of disease can be accurately predicted facilitates the interpretation of outcomes (e.g., biomarkers, trea
Externí odkaz:
https://doaj.org/article/4f27db40cb9d4e8bb9a0fd695fa3831e
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Dorothee Schoemaker, Maria Clara Zanon Zotin, Kewei Chen, Kay C. Igwe, Clara Vila-Castelar, Jairo Martinez, Ana Baena, Joshua T. Fox-Fuller, Francisco Lopera, Eric M. Reiman, Adam M. Brickman, Yakeel T. Quiroz
Publikováno v:
Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-11 (2022)
Abstract Background To promote the development of effective therapies, there is an important need to characterize the full spectrum of neuropathological changes associated with Alzheimer’s disease. In line with this need, this study examined white
Externí odkaz:
https://doaj.org/article/6cea0b3f9fa745c08f5508f5f4e4a33b
Autor:
Hsiang-Han Chen, Abdallah Eteleeb, Ciyang Wang, Maria Victoria Fernandez, John P. Budde, Kristy Bergmann, Joanne Norton, Fengxian Wang, Curtis Ebl, John C. Morris, Richard J. Perrin, Randall J. Bateman, Eric McDade, Chengjie Xiong, Alison Goate, Martin Farlow, Jasmeer Chhatwal, Peter R. Schofield, Helena Chui, Oscar Harari, Carlos Cruchaga, Laura Ibanez, Dominantly Inherited Alzheimer Network
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-11 (2022)
Abstract Background Autosomal-dominant Alzheimer's disease (ADAD) is caused by pathogenic mutations in APP, PSEN1, and PSEN2, which usually lead to an early age at onset (
Externí odkaz:
https://doaj.org/article/bf883b27c2594839a9332c5dd57be351