Zobrazeno 1 - 10
of 769
pro vyhledávání: '"Autoreactivity"'
Autor:
M. Z. Saidov
Publikováno v:
Медицинская иммунология, Vol 25, Iss 1, Pp 7-38 (2023)
The state of autoreactivity of innate immunity dominates in the pathogenesis of immunoinflammatory rheumatic diseases, inducing non-infectious “sterile” inflammation. The distinctive properties of this inflammation include multiorgan affection an
Externí odkaz:
https://doaj.org/article/61d1e68e231740b5b3af16c929e5d246
Akademický článek
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Autor:
Alaitz Aranburu, Erik Engström, Natalija Gerasimcik, Samuel Alsén, Alessandro Camponeschi, Ulf Yrlid, Ola Grimsholm, Inga-Lill Mårtensson
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Immunological memory protects our body from re-infection and it is composed of a cellular and a humoral arm. The B-cell branch with its memory B cells (MBCs), plasma cells and antibodies, formed either in a germinal centre (GC) -dependent or -indepen
Externí odkaz:
https://doaj.org/article/780fd6145b714b46a9ff27077a599e9e
Autor:
Jorge Sánchez, MD, MSc, EAC, PhD, Andres Sánchez Biol, MSc, Marlon Múnera Biol, PhD, Elizabeth García, MD, EAC, Juan-Felipe López, MD, MSc
Publikováno v:
World Allergy Organization Journal, Vol 16, Iss 2, Pp 100742- (2023)
Background: Autoimmune IgG response has been described in the pathogenesis of asthma in adults, but IgE autoimmunity has been little explored. Considering high levels of blood eosinophils and immunoglobulin E in asthmatic patients, the possibility of
Externí odkaz:
https://doaj.org/article/085fe79a9234468885f0022bdb1f8142
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Many of the best HIV-1 broadly neutralizing antibodies (bnAbs) known have poly-/autoreactive features that disfavor normal B cell development and maturation, posing a major hurdle in developing an effective HIV-1 vaccine. Key to resolving this proble
Externí odkaz:
https://doaj.org/article/f1b9f62a94884170848a23b05e2c571e
Autor:
Polly Matzinger
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
For decades, the main question immunologists have asked about autoimmunity is “what causes a break in self-tolerance?” We have not found good answers to that question, and I believe we are still so ignorant because it’s the wrong question. Rath
Externí odkaz:
https://doaj.org/article/21efb28d91df4dec8f8c0d0a482fc458
Autor:
Merle Sauer, Jörg Scheffel, Stefan Frischbutter, Niklas Mahnke, Marcus Maurer, Thomas Burmeister, Karoline Krause, Martin Metz
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundThe pathogenesis of chronic spontaneous urticaria (CSU) has not been clarified entirely. Type IIb autoimmune chronic spontaneous urticaria (CSUaiTIIb) is a distinct subtype of CSU that is often difficult to treat and is connected to low lev
Externí odkaz:
https://doaj.org/article/38ff875985474b7d9f682856efcb4bec
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Antibodies are theoretically limitless in their diversity and specificity to foreign antigens; however they are constrained by the need to avoid binding to self. Germinal centers (GC) allow diversification and maturation of the antibody response towa
Externí odkaz:
https://doaj.org/article/bbdbad66e54e4111ae9cebb859f70819
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
We recently provided evidence for promiscuous recognition of several different hybrid insulin peptides (HIPs) by the highly diabetogenic, I-Ag7-restricted 4.1-T cell receptor (TCR). To understand the structural determinants of this phenomenon, we sol
Externí odkaz:
https://doaj.org/article/8ff2f807b7ef4a5caa0fde1a6a82d4ac
Akademický článek
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