Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Autologous Tumor Cell Vaccine"'
Autor:
Justine Habault, Anna Kaci, Ewa Pasquereau-Kotula, Claire Fraser, Christine Chomienne, Hervé Dombret, Thorsten Braun, Marika Pla, Jean-Luc Poyet
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Despite considerable progress, the treatment of acute leukemia continues to be a challenge for a significant majority of patients. Using a well-characterized preclinical mouse model of acute promyelocytic leukemia (APL), we evaluated here the antileu
Externí odkaz:
https://doaj.org/article/4d272b7d0ff046cea248fea3644850ce
Autor:
Sruthi Ravindranathan, Khue G. Nguyen, Samantha L. Kurtz, Haven N. Frazier, Sean G. Smith, Bhanu prasanth Koppolu, Narasimhan Rajaram, David A. Zaharoff
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-17 (2018)
Abstract Background Although metastasis is ultimately responsible for about 90% of breast cancer mortality, the vast majority of breast-cancer-related deaths are due to progressive recurrences from non-metastatic disease. Current adjuvant therapies a
Externí odkaz:
https://doaj.org/article/3c4716e6a28d4df888466a1360de98b4
Autor:
Jue Wang, Zitong Zhao, Yaping Li, Pengcheng Zhang, Yaping Ding, Dangge Wang, Yanyan Jiang, Lei Fang
Publikováno v:
Science Advances
A feasible and transformable cancer vaccine was designed for personalized immunotherapy of postoperative tumors.
Autologous tumor cell–based vaccines (ATVs) are emerging as a transformable approach for personalized immunotherapy, but their the
Autologous tumor cell–based vaccines (ATVs) are emerging as a transformable approach for personalized immunotherapy, but their the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::402084596aa224bba85f3c31c76a90fd
https://doi.org/10.1126/sciadv.aba4024
https://doi.org/10.1126/sciadv.aba4024
Autor:
Ash A. Alizadeh, Kevin Sheehan, Neel K. Gupta, Debra K. Czerwinski, Malek Faham, Ole Audun Werner Haabeth, Andrew R. Rezvani, Ginna G. Laport, Michael P. Chu, Matthew J. Frank, Irene Wapnir, Sunil Reddy, Michael S. Khodadoust, Everett Meyer, Robert S. Negrin, Ami Okada, David B. Miklos, Ranjana H. Advani, Joshua Brody, Destiny L Phillips, Lauren S. Maeda, Ronald Levy, A Holliston Moore, Wen-Kai Weng
Publikováno v:
The Journal of Experimental Medicine
A CpG-stimulated autologous tumor cell vaccine for patients with MCL is safe and feasible and induces detectable antitumor T cell immune responses. Patients who received the CpG-MCL vaccination demonstrated freedom from MRD at 1 yr after ASCT that su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a089c578c815be0e19c272c165003a5
https://doi.org/10.1084/jem.20191712
https://doi.org/10.1084/jem.20191712
Autor:
Habault, Justine, Kaci, Anna, Pasquereau-Kotula, Ewa, Fraser, Claire, Chomienne, Christine, Dombret, Hervé, Braun, Thorsten, Pla, Marika, Poyet, Jean-Luc
Publikováno v:
OncoImmunology, Vol 9, Iss 1 (2020)
Oncoimmunology
Oncoimmunology
Despite considerable progress, the treatment of acute leukemia continues to be a challenge for a significant majority of patients. Using a well-characterized preclinical mouse model of acute promyelocytic leukemia (APL), we evaluated here the antileu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6bce1ca2921a52afd99c7aaa575d5e2e
https://doaj.org/article/4d272b7d0ff046cea248fea3644850ce
https://doaj.org/article/4d272b7d0ff046cea248fea3644850ce
Autor:
Samantha L. Kurtz, Sruthi Ravindranathan, Bhanu prasanth Koppolu, Haven N. Frazier, Khue G. Nguyen, Sean G. Smith, Narasimhan Rajaram, David A. Zaharoff
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research, Vol 20, Iss 1, Pp 1-17 (2018)
Breast Cancer Research, Vol 20, Iss 1, Pp 1-17 (2018)
Background Although metastasis is ultimately responsible for about 90% of breast cancer mortality, the vast majority of breast-cancer-related deaths are due to progressive recurrences from non-metastatic disease. Current adjuvant therapies are unable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0f4e899f07ff0b96d9d9f9ad312820c
https://doi.org/10.1186/s13058-018-1054-3
https://doi.org/10.1186/s13058-018-1054-3
Autor:
Ernest Bognar, Robert L. Coleman, Luisa Manning, David M. O'Malley, Minal A. Barve, Sharad A. Ghamande, Erin E. Stevens, Thomas J. Herzog, Laura Stanbery, John Nemunaitis, Bradley J. Monk, Phylicia Aaron, Rodney P. Rocconi
Publikováno v:
Journal of Clinical Oncology. 39:5502-5502
5502 Background: In the VITAL (NCT02346747) trial, maintenance therapy with Vigil, an autologous tumor cell vaccine transfected with a DNA plasmid encoding GMCSF and bi-shRNA-furin for TGFβ expression control, following frontline platinum-based chem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::868998cfeaa5eafa52aa249e72930d70
https://doi.org/10.1200/jco.2021.39.15_suppl.5502
https://doi.org/10.1200/jco.2021.39.15_suppl.5502
Autor:
Bradley J. Monk, Devansu Tewari, Erin E. Stevens, Gladice Wallraven, John Nemunaitis, Luisa Manning, Jonathan Oh, Rodney P. Rocconi, John K. Chan, Sharad A. Ghamande, Justin N. Bottsford-Miller, Peter C. Morris, Thomas J. Herzog, Elizabeth A. Grosen, Phylicia Aaron, Ernest Bognar, Min Tang, Minal A. Barve, Brian M. Slomovitz, Robert L. Coleman, Vigil Team
Publikováno v:
Journal of Clinical Oncology. 38:6017-6017
6017 Background: Vigil is an autologous tumor cell vaccine constructed from autologous harvested tumor tissue transfected with a DNA plasmid encoding GMCSF and bi-shRNA-furin thereby creating TGFβ expression control. Methods: A randomized double-bli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d57902b9f63973509d4beb8cad19d60
https://doi.org/10.1200/jco.2020.38.15_suppl.6017
https://doi.org/10.1200/jco.2020.38.15_suppl.6017
Autor:
Alfons J.M. van den Eertwegh, Erik Hooijberg, Saskia J. A. M. Santegoets, Rik J. Scheper, Jorien Harting, Arnold Baars, S. Marieke van Ham, Tanja D. de Gruijl, Bas D. Koster
Publikováno v:
Cancer Immunology, Immunotherapy. 68:1037-1037
In the original publication of the article the following abstract and keywords were inadvertently omitted. Abstract Background In this study the toxicity and efficacy of an irradiated autologous tumor cell vaccine (ATV) co-injected with a class-B CpG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5deb1bf73f47a20466a4a81080501c88
https://doi.org/10.1007/s00262-019-02328-6
https://doi.org/10.1007/s00262-019-02328-6
Autor:
Kazuhiro Yoshimura, Hirotsugu Uemura
Publikováno v:
International Journal of Urology. 20:744-755
Renal cell carcinoma is the most common malignant tumor originating from the kidney. Compared with other solid tumors, it does not respond to traditional management modalities, such as chemotherapy and radiotherapy. However, it is well known that ren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::721524563bd3149d67ed147b559bdc5b
https://doi.org/10.1111/iju.12147
https://doi.org/10.1111/iju.12147