Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Autoimmunity/immunology"'
Autor:
Eelco J.P. de Koning, Bart O. Roep, Henk-Jan Aanstoot, Nicky J C Woittiez, Jaap Jan Zwaginga, Bas S Uitbeijerse, Tatjana Nikolic
Publikováno v:
The Lancet Diabetes & Endocrinology, 8(6), 470-472
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1114ee41caa8f7a8a9ad60efdc42e25
https://doi.org/10.1016/s2213-8587(20)30104-2
https://doi.org/10.1016/s2213-8587(20)30104-2
Autor:
Ingrid Wagner, Giovanni Di Liberto, Doron Merkler, Bogna Klimek, Jonathan Kaye, Nicolas Page, Alexandre Mariotte, Sylvain Lemeille, Ilena Vincenti
Publikováno v:
Nature Communications, Vol. 12, No 1 (2021) P. 1009
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications
Self-reactive CD8+ T cells are important mediators of progressive tissue damage in autoimmune diseases, but the molecular program underlying these cells’ functional adaptation is unclear. Here we characterize the transcriptional and epigenetic land
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::750e0a752bfbd27dac4e81373bedf4ba
https://doi.org/10.1038/s41467-021-21109-3
https://doi.org/10.1038/s41467-021-21109-3
Autor:
Xiangrui Kong, Robbert M. Spaapen, Arnoud H. de Ru, George M.C. Janssen, Sunesh Sethumadhavan, Tamara Verkerk, Frans H.J. Claas, Robert Tampé, Carolin Gerke, Peter A. van Veelen, Marlieke L.M. Jongsma, Arend Mulder, Kelly Hoefakker, Sophie Bliss, Antonius A. de Waard, Anne Halenius
Publikováno v:
European Journal of Immunology
European journal of immunology, 51(3), 734-737. Wiley-VCH Verlag
European journal of immunology, 51(3), 734-737. Wiley-VCH Verlag
A single model system for integrative studies on multiple facets of antigen presentation is lacking. PAKC is a novel panel of ten cell lines knocked out for individual components of the HLA class I antigen presentation pathway. PAKC will accelerate H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::880caccc7d42858052d3d8a15cc9192c
https://hdl.handle.net/1887/3243135
https://hdl.handle.net/1887/3243135
Autor:
Alexander A. Navarini, Curdin Conrad, Alessio Mylonas, Anne-Karine Lapointe, Jeremy Di Domizio, Olivier Demaria, Michel Gilliet, Cyrine Belkhodja, Lars E. French, Maxime Vernez
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
Nature communications, vol. 9, no. 1, pp. 25
Nature Communications
Nature communications, vol. 9, no. 1, pp. 25
Although anti-tumor necrosis factor (TNF) agents are highly effective in the treatment of psoriasis, 2–5% of treated patients develop psoriasis-like skin lesions called paradoxical psoriasis. The pathogenesis of this side effect and its distinction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbbc7decb248c10970a313c075620f0f
https://doaj.org/article/180fc992d72e4fcbbf1d606055e86015
https://doaj.org/article/180fc992d72e4fcbbf1d606055e86015
Publikováno v:
The Israel Medical Association journal : IMAJ. 21(7)
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by the progressive death of motor neurons leading to fatal paralysis. The causes of ALS remain unknown; however, evidence supports the presence of autoimmune mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::dd20487fcc89ba0eeafcab0fe03c7f58
https://pubmed.ncbi.nlm.nih.gov/31507117
https://pubmed.ncbi.nlm.nih.gov/31507117
Autor:
Cornelis R. van der Torren, Ernst-Jan T van 't Wout, Jessica S Suwandi, Pieter Gillard, Frans H.J. Claas, Godelieve Swings, Zhidong Ling, DaHae Lee, Pieter In 'T Veld, Gaby Duinkerken, Bart O. Roep, Bart Keymeulen, Arend Mulder
Publikováno v:
Cell Transplantation, Vol 26 (2017)
Cell Transplantation, 26(1), 1-9
Cell Transplantation, 26(1), 1-9
Transplantation of islet allografts into type 1 diabetic recipients usually requires multiple pancreas donors to achieve insulin independence. This adds to the challenges of immunological monitoring of islet transplantation currently relying on surro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03120b927374e3d4310f24a9d03e09a5
https://doaj.org/article/4fc08ec296f34a08bf92a0beb0387133
https://doaj.org/article/4fc08ec296f34a08bf92a0beb0387133
Increased expression of microRNA miR-326 in type 1 diabetic patients with ongoing islet autoimmunity
Autor:
Fabio Arturo Grieco, Francesco Dotta, Guido Sebastiani, Isabella Spagnuolo, Letizia Galleri, Dorica Cataldo
Publikováno v:
Diabetes/metabolism research and reviews, 27 (8
The current paradigm that microRNAs represent a new layer of gene regulation has generated much interest in this field. MicroRNAs have emerged as important regulatory factors involved in the developmental processes and in the regulation of insulin se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e8a5590f1150207a586d9e4ac15998c
https://doi.org/10.1002/dmrr.1262
https://doi.org/10.1002/dmrr.1262
Autor:
Claire-Anne Siegrist
Publikováno v:
Journal of Comparative Pathology, Vol. 137 Suppl 1 (2007) pp. S46-50
A broad spectrum of adverse events is reported following human vaccination but such reactions are considered to be relatively rare. A variety of mechanisms has been proposed to account for such adverse events. These most commonly relate to the actual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1e259b8f0f9a8ce3b1d89ea97f406ef
https://doi.org/10.1016/j.jcpa.2007.04.012
https://doi.org/10.1016/j.jcpa.2007.04.012
Autor:
Nicole A. Hertzberg, Walter Ferlin, Pauline Malinge, Nadia Anceriz, Mia J. Smith, Laura Cons, Walter Reith, Matthew B. Seefeldt, Ian R. Hardy, Giovanni Magistrelli, Vanessa Buatois, Magali Irla, Guillemette Pontini, François Rousseau, John C. Cambier, Eric Hatterer, Ashley A. Fletcher, Laurence Chatel, Andrew Getahun, Marie Kosco-Vilbois
Publikováno v:
Journal of Immunology, Vol. 192, No 4 (2014) pp. 1641-50
B cells play a major role in the pathogenesis of many autoimmune disorders, including rheumatoid arthritis, systemic lupus erythematosus, multiple sclerosis, and type I diabetes mellitus, as indicated by the efficacy of B cell–targeted therapies in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c0a32a55b8eec2990634818fba6b146
https://pubmed.ncbi.nlm.nih.gov/24442438
https://pubmed.ncbi.nlm.nih.gov/24442438
Autor:
Christian Toso, Colin C. Anderson, Shaheed Merani, A. M. James Shapiro, Rena Pawlick, Ryan Edgar, Juliet Emamaullee
Publikováno v:
Transplantation, Vol. 87, No 1 (2009) pp. 59-65
BACKGROUND: AEB-071 (AEB) is a specific inhibitor of protein kinase C, which prevents T-lymphocyte activation. The present study investigated the effect of AEB on rat islet allotransplantation alone or in combination with CTLA4-Ig, mycophenolate mofe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::711d2ec6ee968f9cd94b7162c788fcc8
https://pubmed.ncbi.nlm.nih.gov/19136892
https://pubmed.ncbi.nlm.nih.gov/19136892