Direct induction of microtubule branching by microtubule nucleation factor SSNA1

Autor: Christian Biertümpfel, Giovanni Cardone, Naoko Mizuno, Alvaro H. Crevenna, Satish Bodakuntla, Thomas Schlichthaerle, Hana Nedozralova, Carsten Janke, Maria M. Magiera, Michael Taschner, Nirakar Basnet, Ralf Jungmann

Publikováno v: Nature Cell Biology
Nature Cell Biology, Nature Publishing Group, 2018, ⟨10.1038/s41556-018-0199-8⟩
Nature cell biology
Nature cell biology, vol. 20, no. 10, pp. 1172-1180

International audience; Microtubules are central elements of the eukaryotic cytoskeleton that often function as part of branched networks. Current models for branching include nucleation of new microtubules from severed microtubule seeds or from gamm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b63531e5f5a41fe085d071ced02502e
https://hal.archives-ouvertes.fr/hal-02375742

Antibody-Mediated Insulin Resistance: When Insulin and Insulin Receptor Act as Autoantigens in Humans

Autor: Emmanuel Disse, Christelle Liminet, Karim Chikh, Julien Vouillarmet

Publikováno v: Canadian Journal of Diabetes
Canadian Journal of Diabetes, Canadian Diabetes Association, 2016, 40 (5), pp.462-465. ⟨10.1016/j.jcjd.2016.02.007⟩

International audience; We report the case of a patient with diabetes presenting a severe insulin-resistance syndrome due to the production of insulin autoantibodies by a lymphocytic lymphoma. We describe the various mechanisms leading to the product

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7331e836d2ab62f79e6d89999d0aaab5
https://hal.archives-ouvertes.fr/hal-01850052

Epigenetic engineering shows H3K4me2 is required for HJURP targeting and CENP-A assembly on a synthetic human kinetochore

Autor: Bergmann, J. H., Rodriguez, M. G., Martins, N. M., Kimura, Hiroshi, Kelly, D. A., Masumoto, H., Larionov, V., Jansen, L. E., Earnshaw, W. C.

Publikováno v: The EMBO journal. 30(No. 2):328-40

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=jairo_______::c3ae8daa38c12c59c56b7d162e2f188a
http://t2r2.star.titech.ac.jp/cgi-bin/publicationinfo.cgi?q_publication_content_number=CTT100733699

Epigenetic engineering: histone H3K9 acetylation is compatible with kinetochore structure and function

Autor: Bergmann, J. H., Jakubsche, J. N., Martins, N. M., Kagansky, A., Nakano, M., Kimura, Hiroshi, Kelly, D. A., Turner, B. M., Masumoto, H., Larionov, V., Earnshaw, W. C.

Publikováno v: Bergmann, J H, Jakubsche, J N, Martins, N M, Kagansky, A, Nakano, M, Kimura, H, Kelly, D A, Turner, B M, Masumoto, H, Larionov, V & Earnshaw, W C 2012, ' Epigenetic engineering: histone H3K9 acetylation is compatible with kinetochore structure and function ', Journal of Cell Science, vol. 125, no. 2, pp. 411-421 . https://doi.org/10.1242/jcs.090639

Human kinetochores are transcriptionally active, producing very low levels of transcripts of the underlying alpha-satellite DNA. However, it is not known whether kinetochores can tolerate acetylated chromatin and the levels of transcription that are

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a571c9f95e4e668f0dfb68ae6a8f9085
https://pubmed.ncbi.nlm.nih.gov/22331359

Allelic variation in key peptide-binding pockets discriminates between closely related diabetes-protective and diabetes-susceptible HLA-DQB1*06 alleles

Autor: Ettinger, R. A., George K Papadopoulos, Moustakas, A. K., Nepom, G. T., Kwok, W. W.

Publikováno v: Scopus-Elsevier

HLA-DQA1*0102-DQB1*0602 is associated with protection against type 1 diabetes (T1D). A similar allele, HLA-DQA1*0102-DQB1*0604, contributes to T1D susceptibility in certain populations but differs only at seven amino acids from HLA-DQA1*0102-DQB1*060

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::7270efc94d5e20ef48d12509419d1cdb
http://www.scopus.com/inward/record.url?eid=2-s2.0-31344435428&partnerID=MN8TOARS