Výsledky vyhledávání - "Autoantibodies/biosynthesis"

Selective autoantibody production by Yaa+ B cells in autoimmune Yaa(+)-Yaa- bone marrow chimeric mice

Autor: Liliane Fossati, Shozo Izui, Marc Lacour, Ramón Merino

Publikováno v: Journal of Experimental Medicine, Vol. 174, No 5 (1991) pp. 1023-1029
The Journal of Experimental Medicine

The accelerated autoimmune syndrome observed in BXSB/MpJ male mice is associated with the presence on the Y chromosome of an as yet unidentified mutant gene, designated Y chromosome-linked autoimmune acceleration (Yaa). To study the mechanisms by whi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e63f3bf87fa12926ea1ee98a95f25c3d
https://doi.org/10.1084/jem.174.5.1023

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Possible reasons for different pattern disappearance of thyroglobulin and thyroid peroxidase autoantibodies in patients with differentiated thyroid carcinoma following total thyroidectomy and iodine-131 ablation

Autor: Agathocles Tsatsoulis, V. Liakos, P. Kaldrimides, E. Vassiliou, Dimitrios Thomas, F. Hatzimarkou

Publikováno v: Journal of endocrinological investigation. 30(3)

The purpose of this study was to reveal some possible factors for the differences between the pattern of disappearance of thyroglobulin autoantibodies (anti-Tg) and thyroid peroxidase autoantibodies (anti-TPO) in patients with differentiated thyroid

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https://pubmed.ncbi.nlm.nih.gov/17505148

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Specific human leukocyte antigen DQ influence on expression of antiislet autoantibodies and progression to type 1 diabetes

Autor: Sunanda R. Babu, Liping Yu, Desmond A. Schatz, Tihamer Orban, David Cuthbertson, Adina Zeidler, Jerry P. Palmer, Maria J. Redondo, George S. Eisenbarth, Jeffrey P. Krischer, Carla J. Greenbaum

Publikováno v: Dadun. Depósito Académico Digital de la Universidad de Navarra
instname

Human leukocyte antigen (HLA) DQ haplotypes have the strongest genetic association with type 1 diabetes (T1DM) risk. OBJECTIVE: The objective of the study was to analyze whether HLA DQ alleles influence the development of antiislet autoantibodies, th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63d309c98528c575016eb8af3bf0aa8a
https://hdl.handle.net/10171/27510

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Association between nuclear antigens and endogenous retrovirus in the generation of autoantibody responses in murine lupus

Autor: Christina L. Roark, Marie-Laure Santiago-Raber, Brian L. Kotzin, Rebecca M. Tucker, Shozo Izui

Publikováno v: Arthritis and Rheumatism, Vol. 50, No 11 (2004) pp. 3626-3636

Objective (NZB × NZW)F1 (NZB/NZW) mice and other strains of mice with experimental lupus frequently produce autoantibodies to both chromatin constituents and murine leukemia virus envelope gp70. These autoantibody responses are involved in the glome

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https://pubmed.ncbi.nlm.nih.gov/15529369

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Dissection of BXSB lupus phenotype using mice congenic for chromosome 1 demonstrates that separate intervals direct different aspects of disease

Autor: Bernard J Morley, Joanna M. Rankin, Aileen McDermott, Mark Walport, Nicola J. Rogers, Shozo Izui, Liliane Fossati-Jimack, Vasuky Thiruudaian, S. Jane Rose, Michelle E. K. Haywood, Margarita Lewis, Joseph J. Boyle

Publikováno v: Journal of Immunology, Vol. 173, No 7 (2004) pp. 4277-4285

To dissect the individual effects of the four non-MHC, autosomal loci (Bxs1 to Bxs4) that contribute to SLE susceptibility in BXSB mice, we generated congenic lines from chromosome 1 on a C57BL/10.YBXSB (B10.Yaa) background for the intervals (values

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https://pubmed.ncbi.nlm.nih.gov/15383556

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Separation of the New Zealand Black genetic contribution to lupus from New Zealand Black determined expansions of marginal zone B and B1a cells

Autor: Stephanie Atencio, Shozo Izui, Brian L. Kotzin, Hirofumi Amano

Publikováno v: Journal of Immunology, Vol. 172, No 7 (2004) pp. 4159-4166

The F1 hybrid of New Zealand Black (NZB) and New Zealand White (NZW) mice develop an autoimmune disease similar to human systemic lupus erythematosus. Because NZB and (NZB × NZW)F1 mice manifest expansions of marginal zone (MZ) B and B1a cells, it h

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https://pubmed.ncbi.nlm.nih.gov/15034028

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Análisis de polimorfismos TAP1 y TAP2 en pacientes del noroeste de Colombia con lupus eritematoso sistémico

Autor: Monica L. Herrera, Juan-Manuel Anaya, Luis Fernando Pinto, Mauricio Arcos-Burgos, Paula A. Correa, Javier Molina

Publikováno v: Repositorio UdeA
Universidad de Antioquia
instacron:Universidad de Antioquia
Annals of the Rheumatic Diseases
Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario

Objective: To determine the influence of TAP1 and TAP2 alleles in northwestern Colombian patients with systemic lupus erythematosus (SLE). Methods: Unselected patients with SLE (n=140) and controls (n=120) matched for sex, age, and ethnicity were ana

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A transgenic mouse model of autoimmune glomerulonephritis and necrotizing arteritis associated with cryoglobulinemia

Autor: Satoru Takahashi, Shozo Izui, Liliane Fossati-Jimack, Robert Lemoine, Thierry Fulpius, Haruyoshi Yoshida, Aki Kuroki, Shuichi Kikuchi, Luc Reininger, Kimi Araki, Yves D. Pastore

Publikováno v: Journal of Immunology, Vol. 169, No 8 (2002) pp. 4644-4650

Mice implanted with hybridoma secreting 6-19 IgG3 anti-IgG2a rheumatoid factor (RF) with cryoglobulin activity develop acute glomerulonephritis and cutaneous leukocytoclastic vasculitis. As the RF activity is implicated in the skin, but not glomerula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06aded1f35277a759e82f3e010f07b4d
https://archive-ouverte.unige.ch/unige:11374

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Selective increase of autoimmune epitope expression on aged erythrocytes in mice: implications in anti-erythrocyte autoimmune responses

Autor: Liliane Fossati-Jimack, Frans A. Kuypers, Per-Arne Oldenborg, Samareh Azeredo da Silveira, Luc Reininger, Thomas Moll, Shozo Izui, Tatsuo Kina

Publikováno v: Journal of Autoimmunity, Vol. 18, No 1 (2002) pp. 17-25

We investigated the impact of changes occurring during red blood cell (RBC) ageing on the RBC-binding activity of pathogenic anti-erythrocyte monoclonal antibodies derived from autoimmune-prone New Zealand black (NZB) mice. As assessed by flow cytome

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d704551873e2802246d89462bd91a6b
https://archive-ouverte.unige.ch/unige:11253

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Autoantigen glycoprotein 70 expression is regulated by a single locus, which acts as a checkpoint for pathogenic anti-glycoprotein 70 autoantibody production and hence for the corresponding development of severe nephritis, in lupus-prone PXSB mice

Autor: Haywood, M. E., Vyse, T. J., McDermott, Aileen, Thompson, E. M., Ida, Akinori, Walport, M. J., Izui, Shozo, Morley, B. J.

Publikováno v: Journal of Immunology, Vol. 167, No 3 (2001) pp. 1728-1733

Retroviral envelope glycoprotein gp70 is present in the sera of immunologically normal and autoimmune-prone strains of mice. However, only lupus-prone mice spontaneously develop gp70-anti-gp70 immune complexes (gp70IC), and these have been implicated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::02228231b66d6b99ec4fe469b89653df
https://pubmed.ncbi.nlm.nih.gov/11466397

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