Le libre accès Une opportunité pour la recherche biomédicale

Autor: Duchange, Nathalie, Autard, Delphine, Pinhas, Nicole

Publikováno v: Duchange, Nathalie and Autard, Delphine and Pinhas, Nicole Le libre accès Une opportunité pour la recherche biomédicale. Médecine/Sciences (Paris), 2008, vol. 24, n. 8-9, pp. 771-775. [Journal article (Paginated)]

Open access within the scientific community depends on the scientific context and the practices of the field. In the biomedical domain, the communication of research is characterised by the importance of the peer reviewing process, the existence of a

Externí odkaz: http://eprints.rclis.org/15954/

Combined Evidence Annotation of Transposable Elements in Genome Sequences.

Autor: Quesneville, Hadi, Bergman, Casey M., Andrieu, Olivier, Autard, Delphine, Nouaud, Danielle, Ashburner, Michael, Anxolabehere, Dominique, Stormo, Gary

Publikováno v: PLoS Computational Biology; Jul2005, Vol. 1 Issue 2, p166-175, 10p, 3 Diagrams, 2 Charts

Identification of an in vivo orally active dual-binding protein-protein interaction inhibitor targeting TNFα through combined in silico/in vitro/in vivo screening

Autor: Rojo Ratsimandresy, Lucille Desallais, Patrick Gizzi, Chouki Zerrouki, Jean Louis Spadoni, Hervé Do, Jean-François Zagury, Bruno Baron, Julie Perrier, Hélène Guillemain, Nesrine Ben Nasr, Matthieu Montes, Patrick England, Najla Fourati, Hadley Mouhsine, Gabriel Moreau

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2017, 7 (1), pp.3424. ⟨10.1038/s41598-017-03427-z⟩
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports, 2017, 7 (1), pp.3424. ⟨10.1038/s41598-017-03427-z⟩
Scientific Reports, Nature Publishing Group, 2017, 7 (1), pp.3424. 〈10.1038/s41598-017-03427-z〉

TNFα is a homotrimeric pro-inflammatory cytokine, whose direct targeting by protein biotherapies has been an undeniable success for the treatment of chronic inflammatory diseases. Despite many efforts, no orally active drug targeting TNFα has been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::206d3e8dd9f7217f02feafc53a96ebf8
https://doi.org/10.1038/s41598-017-03427-z

Farnesyl-transferase inhibitor R115,777 enhances tamoxifen inhibition of MCF-7 cell growth through estrogen receptor dependent and independent pathways

Autor: Florence Dalenc, Gilles Favre, Jean-Charles Faye, Claire Giamarchi, Marc Poirot, Mélissa Petit

Publikováno v: Breast Cancer Research
Breast Cancer Research, BioMed Central, 2005, 7, pp.R1159-67. ⟨10.1186/bcr1357⟩
Breast Cancer Research, 2005, 7, pp.R1159-67. ⟨10.1186/bcr1357⟩

INTRODUCTION: We have previously shown that FTI-277, a farnesyl transferase inhibitor (FTI), enhances the efficacy of tamoxifen (Tam) in inhibiting the proliferation of the estrogen dependent MCF-7 cell line. As the cellular response to Tam is the re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43fdd013d6c4642f63ed1249aa034fda
http://europepmc.org/articles/PMC1410750

Evaluation of atorvastatin efficacy and toxicity on spermatozoa, accessory glands and gonadal hormones of healthy men: a pilot prospective clinical trial

Autor: Florence Brugnon, Joël R. Drevet, Anne-Sophie Gremeau, Bruno Pereira, Laurent Janny, Igor Tauveron, Benoit Sion, Geneviève Grizard, Hanae Pons-Rejraji, Salwan Maqdasy, Geoffroy Marceau, Gerald Gouby

Publikováno v: Reproductive Biology and Endocrinology
Reproductive Biology and Endocrinology, BioMed Central, 2014, 12 (1), ⟨10.1186/1477-7827-12-65⟩
Reproductive Biology and Endocrinology, BioMed Central, 2014, 12 (1), pp.65. ⟨10.1186/1477-7827-12-65⟩
Reproductive Biology and Endocrinology : RB&E
Reprod Biol Endocrinol
Reprod Biol Endocrinol, 2014, 12, pp.65. ⟨10.1186/1477-7827-12-65⟩

International audience; BACKGROUND: Recommendations for cardiovascular disease prevention advocate lowering both cholesterol and low-density lipoprotein cholesterol systemic levels, notably by statin intake. However, statins are the subject of questi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c92c50768a9c9d17d00397dfda5a66a
https://hal.archives-ouvertes.fr/hal-01920020