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of 4
pro vyhledávání: '"Austin W. Cole"'
Autor:
Sanchita Bhadra, Arti Pothukuchy, Raghav Shroff, Austin W Cole, Michelle Byrom, Jared W Ellefson, Jimmy D Gollihar, Andrew D Ellington
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201681 (2018)
We have found that the overproduction of enzymes in bacteria followed by their lyophilization leads to 'cellular reagents' that can be directly used to carry out numerous molecular biology reactions. We demonstrate the use of cellular reagents in a v
Externí odkaz:
https://doaj.org/article/c8cea68c2ab242859670f4198d96c323
Autor:
Isaac Donnell, Raghav Shroff, Daniel J. Diaz, Barrett R. Morrow, Andrew D. Ellington, Ross Thyer, Ankur Annapareddy, Jimmy Gollihar, Austin W. Cole
Publikováno v:
ACS Synthetic Biology. 9:2927-2935
Despite the promise of deep learning accelerated protein engineering, examples of such improved proteins are scarce. Here we report that a 3D convolutional neural network trained to associate amino acids with neighboring chemical microenvironments ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::620342efdd3a1f536dfe8afc0b35414b
https://doi.org/10.1021/acssynbio.0c00345
https://doi.org/10.1021/acssynbio.0c00345
Publikováno v:
Virus evolution. 7(2)
While bacteriophages have previously been used as a model system to understand thermal adaptation, most adapted genomes observed to date contain very few modifications and cover a limited temperature range. Here, we set out to investigate genome adap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c882ff30077b8584c6ea8876f06abae
https://pubmed.ncbi.nlm.nih.gov/35299785
https://pubmed.ncbi.nlm.nih.gov/35299785
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Since the fixation of the genetic code, evolution has largely been confined to 20 proteinogenic amino acids. The development of orthogonal translation systems that allow for the codon-specific incorporation of noncanonical amino acids may provide a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5e46d5e579804bcfbf60ac522b04954
http://europepmc.org/articles/PMC5818497
http://europepmc.org/articles/PMC5818497