Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Austin T. Li"'
Autor:
Bianqin Guo, Xiaopeng Xiong, Sumati Hasani, Yang-An Wen, Austin T. Li, Rebecca Martinez, Ashley T. Skaggs, Tianyan Gao
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-9 (2021)
Abstract Aberrant activation of endoplasmic reticulum (ER) stress by extrinsic and intrinsic factors contributes to tumorigenesis and resistance to chemotherapies in various cancer types. Our previous studies have shown that the downregulation of PHL
Externí odkaz:
https://doaj.org/article/a0a86cb978444043803479dad63bfa72
Autor:
Tianyan Gao, Jean-Paul Borg, Sylvie Marchetto, Masaki Inagaki, Heidi L. Weiss, Tong Gan, Trevor N. Farmer, Ashley T. Stevens, Chi Wang, Austin T. Li, Yekaterina Y. Zaytseva, Xiaopeng Xiong, Yang-An Wen, Payton D. Stevens
Figure S3. Knockout of Erbin has no significant effect on the proliferation and differentiation of normal intestinal epithelial cells. Swiss rolls of intestinal tissues from WT, Erbin+/- (Het) and Erbin-/- (KO) mice were analyzed for the appearance o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e9fc917dda1a79be8b0b83f9afd014
https://doi.org/10.1158/0008-5472.22425808
https://doi.org/10.1158/0008-5472.22425808
Autor:
Tianyan Gao, Jean-Paul Borg, Sylvie Marchetto, Masaki Inagaki, Heidi L. Weiss, Tong Gan, Trevor N. Farmer, Ashley T. Stevens, Chi Wang, Austin T. Li, Yekaterina Y. Zaytseva, Xiaopeng Xiong, Yang-An Wen, Payton D. Stevens
Table S2. Top 25 gene sets that are positively or negatively correlated with Erbin gene expression in CRC.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b527d654a5c74584a38fe352b167450
https://doi.org/10.1158/0008-5472.22425793
https://doi.org/10.1158/0008-5472.22425793
Autor:
Tianyan Gao, Jean-Paul Borg, Sylvie Marchetto, Masaki Inagaki, Heidi L. Weiss, Tong Gan, Trevor N. Farmer, Ashley T. Stevens, Chi Wang, Austin T. Li, Yekaterina Y. Zaytseva, Xiaopeng Xiong, Yang-An Wen, Payton D. Stevens
Erbin belongs to the LAP (leucine-rich repeat and PDZ domain) family of scaffolding proteins that plays important roles in orchestrating cell signaling. Here, we show that Erbin functions as a tumor suppressor in colorectal cancer. Analysis of Erbin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ab848070f830207fc4476fc842e495
https://doi.org/10.1158/0008-5472.c.6512140.v1
https://doi.org/10.1158/0008-5472.c.6512140.v1
Autor:
Trevor N. Farmer, Xiaopeng Xiong, Heidi L. Weiss, Tianyan Gao, B. Mark Evers, Ashley T. Stevens, Yang-An Wen, Sanam Golshani, Tong Gan, Austin T. Li, Payton D. Stevens
Publikováno v:
Oncogene
Wnt signaling dysregulation promotes tumorigenesis in colorectal cancer (CRC). We investigated the role of PTPRF, a receptor-type tyrosine phosphatase, in regulating Wnt signaling in CRC. Knockdown of PTPRF decreased cell proliferation in patient-der
Autor:
Tianyan Gao, Bianqin Guo, Sumati Hasani, Xiaopeng Xiong, Ashley T. Skaggs, Rebecca Martinez, Austin T. Li, Yang-An Wen
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-9 (2021)
Cell Death & Disease
Cell Death & Disease
Aberrant activation of endoplasmic reticulum (ER) stress by extrinsic and intrinsic factors contributes to tumorigenesis and resistance to chemotherapies in various cancer types. Our previous studies have shown that the downregulation of PHLPP, a nov
Autor:
Austin T. Li, Xiaopeng Xiong, Li Tan, Terrence A. Barrett, Timothy L. Scott, Chi Wang, Tianyan Gao, Heidi L. Weiss, Emily M. Bradford, Teresa W.-M. Fan, Navdeep S. Chandel, Yang An Wen
Publikováno v:
Cell Death Differ
Cancer cells are known to upregulate aerobic glycolysis to promote growth, proliferation, and survival. However, the role of mitochondrial respiration in tumorigenesis remains elusive. Here we report that inhibition of mitochondrial function by silen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63fadd1b33a34eba0e4d4c9dfeb40a07
https://europepmc.org/articles/PMC6748256/
https://europepmc.org/articles/PMC6748256/
Autor:
Dana Napier, Xiaopeng Xiong, Emma Vallee, Austin T. Li, Heidi L. Weiss, Tianyan Gao, Yang-An Wen, Yekaterina Y. Zaytseva, Chi Wang, B. Mark Evers
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 9, Iss 3, Pp 1-14 (2018)
Cell Death and Disease, Vol 9, Iss 3, Pp 1-14 (2018)
Sterol regulatory element-binding proteins (SREBPs) belong to a family of transcription factors that regulate the expression of genes required for the synthesis of fatty acids and cholesterol. Three SREBP isoforms, SREBP1a, SREBP1c, and SREBP2, have
Autor:
Heidi L. Weiss, Chi Wang, Ashley T. Stevens, Trevor N. Farmer, Tong Gan, Austin T. Li, Yang-An Wen, Payton D. Stevens, Jean-Paul Borg, Yekaterina Y. Zaytseva, Sylvie Marchetto, Xiaopeng Xiong, Tianyan Gao, Masaki Inagaki
Publikováno v:
Cancer Research
Cancer Research, American Association for Cancer Research, 2018, 78 (17), pp.4839-4852. ⟨10.1158/0008-5472.CAN-17-3629⟩
Cancer Research, 2018, 78 (17), pp.4839-4852. ⟨10.1158/0008-5472.CAN-17-3629⟩
Cancer Research, American Association for Cancer Research, 2018, 78 (17), pp.4839-4852. ⟨10.1158/0008-5472.CAN-17-3629⟩
Cancer Research, 2018, 78 (17), pp.4839-4852. ⟨10.1158/0008-5472.CAN-17-3629⟩
Erbin belongs to the LAP (leucine-rich repeat and PDZ domain) family of scaffolding proteins that plays important roles in orchestrating cell signaling. Here, we show that Erbin functions as a tumor suppressor in colorectal cancer. Analysis of Erbin