Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Austin N. Oleskie"'
Autor:
Somnath Dutta, Austin N. Oleskie, Colin A. Kretz, Andrew Yee, David Ginsburg, Robert D. Gildersleeve, Anne M. Dosey, Georgios Skiniotis, Min Su
Publikováno v:
Blood. 126:939-942
Binding to the von Willebrand factor (VWF) D′D3 domains protects factor VIII (FVIII) from rapid clearance. We performed single-particle electron microscopy (EM) analysis of negatively stained specimens to examine the architecture of D′D3 alone an
Autor:
Sachdev S. Sidhu, Brian K. Kobilka, Xin Chen, Li-Yin Huang, Arun K. Shukla, Austin N. Oleskie, Minjung Choi, Sheng Li, Ling Ling Gu, Anthony A. Kossiakoff, Jiang Qian, Gerwin Westfield, Rosana I. Reis, Robert J. Lefkowitz, Shohei Koide, Alem W. Kahsai, Georgios Skiniotis, Jin Ming Shan, Adi Blanc, Prachi Tripathi-Shukla, Pawel A. Penczek, Cui Rong Liang, Rachel Hanna, Anne M. Dosey, Bjoern U. Klink, Xiao Jie Yao, Kunhong Xiao, Min Su, Virgil L. Woods
Publikováno v:
Nature
Single-particle electron microscopy and hydrogen–deuterium exchange mass spectrometry are used to characterize the structure and dynamics of a G-protein-coupled receptor–arrestin complex. Much has been learned about the structure of G-protein-cou
Autor:
Austin N. Oleskie, Jeffrey F. Herbstman, Gerwin Westfield, Liliya V. Mancour, Georgios Skiniotis, Steven Z. Chou, Justin Schilling, Hikmat N. Daghestani, Somnath Dutta
Publikováno v:
Molecular Cell. 48(4):655-661
Despite the crucial impact of leptin signaling on metabolism and body weight, little is known about the structure of the liganded leptin receptor (LEP-R) complex. Here, we applied single-particle electron microscopy (EM) to characterize the architect
Autor:
Liliya V. Mancour, Austin N. Oleskie, Mariam Ayyash, Mohamed E. Abazeed, Mithu De, Georgios Skiniotis, Somnath Dutta, Robert S. Fuller, Eddy J. Brace
Publikováno v:
The Journal of Cell Biology
Myers and Payne discuss work by De et al. describing the unique structure of Vps13 and its role in trafficking
Yeast Vps13 is a member of a conserved protein family that includes human homologues associated with neurodegenerative and development
Yeast Vps13 is a member of a conserved protein family that includes human homologues associated with neurodegenerative and development
Autor:
Austin N. Oleskie, Raymond C. Trievel, Gerwin Westfield, Yoh Hei Takahashi, Georgios Skiniotis, Ali Shilatifard
Publikováno v:
Proceedings of the National Academy of Sciences. 108:20526-20531
Histone H3 lysine 4 (H3K4) methylation is catalyzed by the highly evolutionarily conserved multiprotein complex known as Set1/COMPASS or MLL/COMPASS-like complexes from yeast to human, respectively. Here we have reconstituted fully functional yeast S
Autor:
Erin C. Rericha, Austin N. Oleskie
Publikováno v:
Biophysical Journal. 110:128a
Over the last two decades, experimental results have shown the response of uniform entangled actin networks to local stresses and strains is nonlinear. One theory proposes that nonlinear stresses associated with large network strains arise from gradi
Autor:
Gerwin H, Westfield, Søren G F, Rasmussen, Min, Su, Somnath, Dutta, Brian T, DeVree, Ka Young, Chung, Diane, Calinski, Gisselle, Velez-Ruiz, Austin N, Oleskie, Els, Pardon, Pil Seok, Chae, Tong, Liu, Sheng, Li, Virgil L, Woods, Jan, Steyaert, Brian K, Kobilka, Roger K, Sunahara, Georgios, Skiniotis
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 108(38)
The active-state complex between an agonist-bound receptor and a guanine nucleotide-free G protein represents the fundamental signaling assembly for the majority of hormone and neurotransmitter signaling. We applied single-particle electron microscop
Autor:
Min Su, Brian T. DeVree, Sheng Li, Gisselle A. Vélez-Ruiz, Diane Calinski, Austin N. Oleskie, Brian Kobilka, Tong Liu, Gerwin Westfield, Pil Seok Chae, Ka Young Chung, Jan Steyaert, Søren G. F. Rasmussen, Georgios Skiniotis, Roger K. Sunahara, Somnath Dutta, Els Pardon, Virgil L. Woods
The active-state complex between an agonist-bound receptor and a guanine nucleotide-free G protein represents the fundamental signaling assembly for the majority of hormone and neurotransmitter signaling. We applied single-particle electron microscop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5746106cccece398f3bb1dac3ee6594
https://hdl.handle.net/20.500.14017/1ec7f3e8-0dff-4bb8-8d72-d8fd57f34278
https://hdl.handle.net/20.500.14017/1ec7f3e8-0dff-4bb8-8d72-d8fd57f34278
Autor:
Austin N. Oleskie, Colin A. Kretz, Andrew Yee, Beth McGee, Robert D. Gildersleeve, Keisha M. Carr, David Ginsburg, Georgios Skiniotis, Min Su
Publikováno v:
Blood. 120:15-15
Abstract 15 Plasma factor VIII (fVIII) circulates in complex with von Willebrand factor (VWF) and is rapidly cleared in the absence of VWF. Previous in vitro studies have 1) localized the fVIII-binding region of VWF to the N-terminus, comprised of th