Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Austin K Mircheff"'
Autor:
Ian A. Jones, Melissa Wilson, Ryan Togashi, Bo Han, Austin K. Mircheff, C. Thomas Vangsness JR
Publikováno v:
BMC Musculoskeletal Disorders, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Background Osteoarthritis (OA) is a highly debilitating joint disease that causes progressive, irreversible damage to articular cartilage. OA takes a massive toll on society that has grown in recent decades, but no therapy has been shown to
Externí odkaz:
https://doaj.org/article/2e1ae2372a6f48b3899b3a130cb486b3
Publikováno v:
BMC Musculoskeletal Disorders, Vol 19, Iss 1, Pp 1-11 (2018)
BMC Musculoskeletal Disorders
BMC Musculoskeletal Disorders
Background Osteoarthritis (OA) is a highly debilitating joint disease that causes progressive, irreversible damage to articular cartilage. OA takes a massive toll on society that has grown in recent decades, but no therapy has been shown to halt or r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::452127c4abac9fb3fa614885fb0274d2
http://link.springer.com/article/10.1186/s12891-018-2300-7
http://link.springer.com/article/10.1186/s12891-018-2300-7
Publikováno v:
The Ocular Surface. 16:120-131
Purpose This study asked whether pregnancy, a risk factor for dry eye disease associated with both chronic, immune-mediated- and autoimmune etiologies, augments development of clusters of coordinately functioning cells (CCFC) that may be precursors t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6e4124423a95afad47b0a6155a8566
https://doi.org/10.1016/j.jtos.2017.09.005
https://doi.org/10.1016/j.jtos.2017.09.005
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 1, p 223 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 1
International Journal of Molecular Sciences
Volume 20
Issue 1
Understanding the formation of Sjogren&rsquo
s lymphocytic infiltrates could permit earlier diagnosis and better outcomes. We submitted gene transcript abundances in histologically normal rabbit lacrimal glands to principal component analysis. T
s lymphocytic infiltrates could permit earlier diagnosis and better outcomes. We submitted gene transcript abundances in histologically normal rabbit lacrimal glands to principal component analysis. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee9c9441d7ab4af0846e2e621c165423
http://www.mdpi.com/1422-0067/20/1/223
http://www.mdpi.com/1422-0067/20/1/223
Autor:
Melvin D. Trousdale, Austin K. Mircheff, Padmaja B. Thomas, Rui Hua Wei, Joel E. Schechter, D. M. Samant
Publikováno v:
Cornea. 31:693-701
PURPOSE Autologous peripheral blood lymphocytes, activated in a mixed cell reaction when cocultured with purified rabbit lacrimal epithelial cells, are known to induce a severe autoimmune dacryoadenitis when injected directly into the donor animal's
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96dbb4ce6524e49a37ba8730dee39c7f
https://doi.org/10.1097/ico.0b013e31823f8e47
https://doi.org/10.1097/ico.0b013e31823f8e47
Autor:
D. M. Samant, Melvin D. Trousdale, Douglas Stevenson, Joel E. Schechter, Shivaram Selvam, John D Gray, Yanru Wang, Austin K. Mircheff, Padmaja B. Thomas
Publikováno v:
Cornea. 29:1153-1162
PURPOSE To test whether CD4+ T cells proliferate in mixed cell reactions with autologous lacrimal gland (LG) acinar cells and whether these cells can autoadoptively transfer disease. METHODS Purified acinar cells were gamma irradiated and cocultured
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2659f4965c70d436624923e7ec47f2ad
https://doi.org/10.1097/ico.0b013e3181d0090e
https://doi.org/10.1097/ico.0b013e3181d0090e
Publikováno v:
The Ocular Surface. 8:111-134
Research into the physiological processes governing both normal and abnormal functions of the lacrimal gland has used animal models to provide insights that might be applied to improving our understanding of human disease and designing of beneficial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af8135bf88f45626aa0432fe7032e2b1
https://doi.org/10.1016/s1542-0124(12)70222-7
https://doi.org/10.1016/s1542-0124(12)70222-7
Autor:
Yanru Wang, M. De Saint Jean, Austin K. Mircheff, Joel E. Schechter, Melvin D. Trousdale, T. Nakamura
Publikováno v:
Scandinavian Journal of Immunology. 70:53-62
Lacrimal epithelial cells appear to constitutively secrete autoantigens to their underling stroma. The present experiments address the hypothesis that they also secrete soluble factors that regulate immune responses. Epithelial cells, spleen cells an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0df4683c622fac238c59cb09e192717
https://doi.org/10.1111/j.1365-3083.2009.02272.x
https://doi.org/10.1111/j.1365-3083.2009.02272.x
Autor:
D. M. Samant, Padmaja B. Thomas, Z. Zhu, Melvin D. Trousdale, Sang W. Song, Shivaram Selvam, Douglas Stevenson, Yanru Wang, Austin K. Mircheff, Joel E. Schechter, Samuel C. Yiu
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 25:285-291
To use a rabbit model of induced autoimmune dacryoadenitis to evaluate the efficacy of topical ophthalmic cyclosporine A (CsA).Autoimmune dacryoadenitis was induced by injecting autologous peripheral blood lymphocytes, which had been activated in a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5cbdd3f7ed05f3f279b0cd7a3b2c190
https://doi.org/10.1089/jop.2008.0138
https://doi.org/10.1089/jop.2008.0138
Autor:
Shivaram Selvam, S.W. Song, Melvin D. Trousdale, Douglas Stevenson, Joel E. Schechter, Austin K. Mircheff, D. M. Samant, Padmaja B. Thomas, Z. Zhu
Publikováno v:
Journal of Autoimmunity. 31:116-122
Autologous peripheral blood lymphocytes (PBL), activated in a mixed cell reaction when co-cultured with purified rabbit lacrimal epithelial cells, are known to induce a Sjőgren’s-like autoimmune dacryoadenitis and keratoconjunctivitis when injecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f793a60cff924c25e3d837580062d19
https://doi.org/10.1016/j.jaut.2008.04.019
https://doi.org/10.1016/j.jaut.2008.04.019