Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Austin J. Jolly"'
Autor:
Stephanie E. Ander, Kathryn S. Carpentier, Wes Sanders, Cormac J. Lucas, Austin J. Jolly, Cydney N. Johnson, David W. Hawman, Mark T. Heise, Nathaniel J. Moorman, Thomas E. Morrison
Publikováno v:
Viruses, Vol 16, Iss 6, p 861 (2024)
We previously reported that deletion of a 44-nucleotide element in the 3′ untranslated region (UTR) of the Chikungunya virus (CHIKV) genome enhances the virulence of CHIKV infection in mice. Here, we find that while this 44-nucleotide deletion enha
Externí odkaz:
https://doaj.org/article/de9d1c236b594b4e9eb72f3e4301308c
Autor:
Allison M. Dubner, Sizhao Lu, Austin J. Jolly, Keith A. Strand, Marie F. Mutryn, Tyler Hinthorn, Tysen Noble, Raphael A. Nemenoff, Karen S. Moulton, Mark W. Majesky, Mary C.M. Weiser-Evans
Publikováno v:
JCI Insight, Vol 8, Iss 22 (2023)
We previously established that vascular smooth muscle–derived adventitial progenitor cells (AdvSca1-SM) preferentially differentiate into myofibroblasts and contribute to fibrosis in response to acute vascular injury. However, the role of these pro
Externí odkaz:
https://doaj.org/article/457a71ce90e84954826e313a6a63b0aa
Autor:
Austin J. Jolly, Sizhao Lu, Allison M. Dubner, Keith A. Strand, Marie F. Mutryn, Aaron Pilotti-Riley, Etienne P. Danis, Raphael A. Nemenoff, Karen S. Moulton, Mark W. Majesky, Mary C.M. Weiser-Evans
Publikováno v:
JCI Insight, Vol 8, Iss 9 (2023)
Vascular smooth muscle–derived Sca1+ adventitial progenitor (AdvSca1-SM) cells are tissue-resident, multipotent stem cells that contribute to progression of vascular remodeling and fibrosis. Upon acute vascular injury, AdvSca1-SM cells differentiat
Externí odkaz:
https://doaj.org/article/f28d2456ad89429599aa18fbc319991c
Autor:
Sizhao Lu, Austin J. Jolly, Keith A. Strand, Allison M. Dubner, Marie F. Mutryn, Karen S. Moulton, Raphael A. Nemenoff, Mark W. Majesky, Mary C.M. Weiser-Evans
Publikováno v:
JCI Insight, Vol 5, Iss 23 (2020)
Resident vascular adventitial SCA1+ progenitor (AdvSca1) cells are essential in vascular development and injury. However, the heterogeneity of AdvSca1 cells presents a unique challenge in understanding signaling pathways orchestrating their behavior
Externí odkaz:
https://doaj.org/article/6757c5fc0e5a449ba35f422f50f7244a
Autor:
Marie F Mutryn, Keith A. Strand, Raphael A. Nemenoff, Sizhao Lu, Austin J Jolly, Mary C.M. Weiser-Evans, Allison M. Dubner, Mark W. Majesky, Karen S. Moulton
Publikováno v:
Cardiovasc Res
Cardiovascular diseases are characterized by chronic vascular dysfunction and provoke pathological remodelling events, such as neointima formation, atherosclerotic lesion development, and adventitial fibrosis. While lineage-tracing studies have shown
Autor:
Sizhao Lu, Austin J Jolly, Allison M Dubner, Marie F Mutryn, Raphael A Nemenoff, Karen S Moulton, Mary C Weiser-Evans
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 42
Activated cardiac myofibroblasts are the major contributors to ECM deposition in pathological cardiovascular fibrosis, which is the characteristic feature of cardiovascular diseases. However, due to potential heterogeneity of myofibroblasts, the orig
Autor:
Jonathan T. Bravman, Ilona Schwarz, Rachel M. Frank, Darby A. Houck, Viral N. Shah, Adam Lindsay, Austin J Jolly
Publikováno v:
The Journal of Sports Medicine and Physical Fitness. 62
BACKGROUND Freestyle skiers must optimize their aerial performance by maintaining the strength and coordination to propel themselves in the air and adapt to landings and take-offs on uneven surfaces. The purpose of this study is to investigate the di
Autor:
Qiong Zhou, Raphael A. Nemenoff, Mary C.M. Weiser-Evans, Sizhao Lu, Allison M. Dubner, Keith A. Koch, Austin J Jolly, Daniel V. LaBarbera, Blake T. Enyart, Linfeng Li, Keith A. Strand, Karen S. Moulton, Marie F Mutryn
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: Our recent work demonstrates that PTEN (phosphatase and tensin homolog) is an important regulator of smooth muscle cell (SMC) phenotype. SMC-specific PTEN deletion promotes spontaneous vascular remodeling and PTEN loss correlates with incr
Autor:
Karen S. Moulton, Marie F Mutryn, Austin J Jolly, Keith A. Strand, Mary C.M. Weiser-Evans, Seth B. Furgeson, Rebecca M. Tucker, Raphael A. Nemenoff, Sizhao Lu
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: Pathological vascular remodeling and excessive perivascular fibrosis are major contributors to reduced vessel compliance that exacerbates cardiovascular diseases, for instance, promoting clinically relevant myocardial remodeling. Inflammat
Autor:
Mary C.M. Weiser-Evans, Allison M. Dubner, Austin J Jolly, Mark W. Majesky, Raphael A. Nemenoff, Karen S. Moulton, Marie F Mutryn, Keith A. Strand, Sizhao Lu
Publikováno v:
JCI Insight, Vol 5, Iss 23 (2020)
JCI Insight
JCI Insight
Resident vascular adventitial SCA1+ progenitor (AdvSca1) cells are essential in vascular development and injury. However, the heterogeneity of AdvSca1 cells presents a unique challenge in understanding signaling pathways orchestrating their behavior