Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Austin J. Gutierrez"'
Autor:
Linh T. Bui, Nichelle I. Winters, Mei-I Chung, Chitra Joseph, Austin J. Gutierrez, Arun C. Habermann, Taylor S. Adams, Jonas C. Schupp, Sergio Poli, Lance M. Peter, Chase J. Taylor, Jessica B. Blackburn, Bradley W. Richmond, Andrew G. Nicholson, Doris Rassl, William A. Wallace, Ivan O. Rosas, R. Gisli Jenkins, Naftali Kaminski, Jonathan A. Kropski, Nicholas E. Banovich, Human Cell Atlas Lung Biological Network
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Patients with chronic lung disease (CLD) have an increased risk for severe coronavirus disease-19 and poor outcomes. Here the authors compare the transcriptomes of single cells isolated from healthy and CLD lungs to identify molecular characteristics
Externí odkaz:
https://doaj.org/article/8c96b7d10ceb4972b8de290313cf45fb
Autor:
Jessica B. Blackburn, Jacob A. Schaff, Sergey Gutor, Rui-Hong Du, David Nichols, Taylor Sherrill, Austin J. Gutierrez, Matthew K. Xin, Nancy Wickersham, Yong Zhang, Michael J. Holtzman, Lorraine B. Ware, Nicholas E. Banovich, Jonathan A. Kropski, Timothy S. Blackwell, Bradley W. Richmond
Publikováno v:
American journal of respiratory cell and molecular biology. 67(3)
Loss of secretory IgA (SIgA) is common in chronic obstructive pulmonary disease (COPD) small airways and likely contributes to disease progression. We hypothesized that loss of SIgA results from reduced expression of pIgR (polymeric immunoglobulin re
Autor:
Nicholas E. Banovich, Robert Lafyatis, Laura E. Niklason, Kerstin B. Meyer, Dana Pe'er, Carlos Cosme, Yifan Yuan, Taylor Adams, Austin J. Gutierrez, Maor Sauler, Maurizio Chioccioli, Kadi-Ann Rose, Edward P. Manning, Jonathan A. Kropski, Sergio Poli, Norihito Omote, Xiting Yan, Farida Ahangari, Nir Neumark, Jonas C. Schupp, Arun C. Habermann, Richard W. Pierce, Linh T. Bui, Giuseppe DeIuliis, Micha Sam Brickman Raredon, Martijn C. Nawijn, Robert J. Homer, Naftali Kaminski, Ivan O. Rosas, Sarah A. Teichmann
Publikováno v:
Circulation, 144(4), 286-302. LIPPINCOTT WILLIAMS & WILKINS
Circulation
Circulation
Supplemental Digital Content is available in the text.
Background: Cellular diversity of the lung endothelium has not been systematically characterized in humans. We provide a reference atlas of human lung endothelial cells (ECs) to facilitate a
Background: Cellular diversity of the lung endothelium has not been systematically characterized in humans. We provide a reference atlas of human lung endothelial cells (ECs) to facilitate a
Autor:
Jessica B. Blackburn, Jae-Woo Lee, Rui-Hong Du, Nancy Wickersham, David Nichols, Matthew K. Xin, Yong Zhang, Taylor P. Sherrill, Bradley W. Richmond, Vasiliy V. Polosukhin, Michael J. Holtzman, Austin J. Gutierrez, Nicholas E. Banovich, Jonathan A. Kropski, Timothy S. Blackwell, Lorraine B. Ware, Jacob A. Schaff, Sergey Gutor
BackgroundLoss of secretory immunoglobulin A (SIgA) is common in COPD small airways and likely contributes to disease progression. We hypothesized loss of SIgA results from reduced expression of pIgR, a chaperone protein needed for SIgA transcytosis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0a6bd6ae92f3dba619e8796691e954c
https://doi.org/10.1101/2021.11.10.467794
https://doi.org/10.1101/2021.11.10.467794
Autor:
Austin J. Gutierrez, Jonathan A. Kropski, Jason J. Gokey, Christopher S. Jetter, Chase J. Taylor, Jane E. Camarata, Nicholas E. Banovich, Linh T. Bui, Matthew Bacchetta, Nichelle I. Winters, Jennifer M.S. Sucre
Precision-cut lung slices (PCLS) are increasingly utilized for ex vivo disease modeling, but a high-resolution characterization of cellular phenotype stability in PCLS has not been reported. Comparing the single-cell transcriptomic profile of human P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0ff624c3f4d79b8d909c4fa3bfbbb0c
https://doi.org/10.1101/2021.08.19.457016
https://doi.org/10.1101/2021.08.19.457016
Autor:
Nichelle I. Winters, Taylor Adams, Jessica B. Blackburn, Mei-I Chung, Andrew G. Nicholson, William A Wallace, Bradley W. Richmond, Naftali Kaminski, Jonas C. Schupp, Sergio Poli, Linh T. Bui, Austin J. Gutierrez, Lance M. Peter, Chase J. Taylor, Chitra Joseph, Ivan O. Rosas, Jonathan A. Kropski, R. Gisli Jenkins, Arun C. Habermann, Doris Rassl, Nicholas E. Banovich
Publikováno v:
Nature Communications, 12(1):4314. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Patients with chronic lung disease (CLD) have an increased risk for severe coronavirus disease-19 (COVID-19) and poor outcomes. Here, we analyze the transcriptomes of 611,398 single cells isolated from healthy and CLD lungs to identify molecular char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93c3c96e7485734a7e7e44b05fc005a3
https://research.rug.nl/en/publications/ad01d54a-3745-4a72-9ee7-b5193dd49e2c
https://research.rug.nl/en/publications/ad01d54a-3745-4a72-9ee7-b5193dd49e2c
Autor:
Linh T. Bui, Heini M. Natri, Lance M. Peter, Bianca Argente, Austin J. Gutierrez, Arnold Federico, Mei-I Chung, Jonathan Keats, Nicholas E. Banovich
Publikováno v:
Cancer Research. 82:5780-5780
Multiple myeloma (MM) is a malignancy of plasma cells in the bone marrow and the second most common hematological malignancy. MM is characterized by a high degree of heterogeneity and has a hereditary genetic component with relatives of MM patients h
Autor:
Christine E. Brown, Sophia Zhang, Renate Starr, Austin J. Gutierrez, Lance M. Peter, Nicholas E. Banovich, Darya Alizadeh, Stephanie L. Yahn, Mei-I Chung
Publikováno v:
Neuro Oncol
Recent advances in immunotherapy, particularly chimeric antigen receptor (CAR)-engineered T cell therapy, have shown promise for the treatment of many tumor types including progressive recurrent glioblastoma (GBM). While early phase clinical trials h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8346bcb2d33a2cd431a8afbf13822f79
https://europepmc.org/articles/PMC7651225/
https://europepmc.org/articles/PMC7651225/
Autor:
Ivan O. Rosas, Xiting Yan, Yifan Yuan, Sarah A. Teichmann, Maor Sauler, Edward P. Manning, Dana Pe'er, Carlos Cosme, Laura E. Niklason, Linh T. Bui, Jonathan A. Kropski, Norihito Omote, Giuseppe DeIuliis, Micha Sam Brickman Raredon, Taylor Adams, Jonas C. Schupp, Martijn C. Nawijn, Naftali Kaminski, Austin J. Gutierrez, Kerstin B. Meyer, Nicholas E. Banovich, Sergio Poli De Frias, Farida Ahangari, Robert J. Homer, Nir Neumark, Kadi-Ann Rose, Arun C. Habermann
BackgroundDespite its importance in health and disease, the cellular diversity of the lung endothelium has not been systematically characterized in humans. Here we provide a reference atlas of human lung endothelial cells (ECs), to facilitate a bette
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0c59b91dc5098ee30e96a54227812c3
https://doi.org/10.1101/2020.10.21.347914
https://doi.org/10.1101/2020.10.21.347914
Autor:
Nichelle I. Winters, Jennifer M.S. Sucre, Carla L. Calvi, Linh T. Bui, Ana P. Serezani, Ross M. Bremner, Simon B. Mallal, Rajat Walia, Matthew J. Bacchetta, Lorraine B. Ware, Chase J. Taylor, Jamie Roberson, Wyatt J. McDonnell, Ciara M. Shaver, Bradley W. Richmond, Austin J. Gutierrez, Lance M. Peter, James E. Loyd, Christopher S. Jetter, Timothy S. Blackwell, Jonathan A. Kropski, Nicholas E. Banovich, Stephanie L. Yahn, Latha Raju, Lori Wood, Guixiao Ding, Arun C. Habermann, Mei-I Chung
Publikováno v:
Science Advances
Single-cell RNA sequencing provides new insights into pathologic epithelial and mesenchymal remodeling in the human lung.
Pulmonary fibrosis (PF) is a form of chronic lung disease characterized by pathologic epithelial remodeling and accumulatio
Pulmonary fibrosis (PF) is a form of chronic lung disease characterized by pathologic epithelial remodeling and accumulatio