Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Austin J Cooney"'
Autor:
Davood Sabour, Xueping Xu, Arthur C K Chung, Damien Le Menuet, Kinarm Ko, Natalia Tapia, Marcos J Araúzo-Bravo, Luca Gentile, Boris Greber, Karin Hübner, Vittorio Sebastiano, Guangming Wu, Hans R Schöler, Austin J Cooney
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103985 (2014)
Expression of germ cell nuclear factor (GCNF; Nr6a1), an orphan member of the nuclear receptor gene family of transcription factors, during gastrulation and neurulation is critical for normal embryogenesis in mice. Gcnf represses the expression of th
Externí odkaz:
https://doaj.org/article/6bd9621759ce419f8cd31e4696f47942
Autor:
Sujeivan Mahendram, Kevin F Kelly, Sabrina Paez-Parent, Sharmeen Mahmood, Enio Polena, Austin J Cooney, Bradley W Doble
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e65320 (2013)
β-catenin, an adherens junction component and key Wnt pathway effector, regulates numerous developmental processes and supports embryonic stem cell (ESC) pluripotency in specific contexts. The β-catenin homologue γ-catenin (also known as Plakoglob
Externí odkaz:
https://doaj.org/article/5685148b589644f8bf7b8c2661c28d94
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63532 (2013)
Embryonic stem (ES) cells have several unique attributes, the two most important of which are they can differentiate into all cell types in the body and they can proliferate indefinitely. To study the regulation of these phenomena, we developed a reg
Externí odkaz:
https://doaj.org/article/49b562fbf75a4a7cb7bec6826c3cf177
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74556 (2013)
Loss of Dicer, an enzyme critical for microRNA biogenesis, results in lethality due to a block in mouse embryonic stem cell (mES) differentiation. Using ChIP-Seq we found increased H3K9me2 at over 900 CpG islands in the Dicer(-/-)ES epigenome. Gene o
Externí odkaz:
https://doaj.org/article/6b7fbb757ae84043be2df12fd2b2e3dc
Autor:
Zijun Luo, Xuping Xu, Peili Gu, David Lonard, Preethi H Gunaratne, Austin J Cooney, Robert Azencott
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e23263 (2011)
MicroRNAs (miRNAs) play an important role in gene regulation for Embryonic Stem cells (ES cells), where they either down-regulate target mRNA genes by degradation or repress protein expression of these mRNA genes by inhibiting translation. Well known
Externí odkaz:
https://doaj.org/article/6d55613c686c458e9f1edc0ca644f9ff
Autor:
Peili Gu, Jeffrey G Reid, Xiaolian Gao, Chad A Shaw, Chad Creighton, Peter L Tran, Xiaochuan Zhou, Rafal B Drabek, David L Steffen, David M Hoang, Michelle K Weiss, Arash O Naghavi, Jad El-daye, Mahjabeen F Khan, Glen B Legge, David A Wheeler, Richard A Gibbs, Jonathan N Miller, Austin J Cooney, Preethi H Gunaratne
Publikováno v:
PLoS ONE, Vol 3, Iss 7, p e2548 (2008)
MicroRNAS (miRNAS: a class of short non-coding RNAs) are emerging as important agents of post transcriptional gene regulation and integral components of gene networks. MiRNAs have been strongly linked to stem cells, which have a remarkable dual role
Externí odkaz:
https://doaj.org/article/fa0e98b63c60468398a4c6e40e88f2e7
Autor:
Huacheng Luo, Xiaoyong Li, Geng G. Tian, Dali Li, Changliang Hou, Xinbao Ding, Lin Hou, Qifeng Lyu, Yunze Yang, Austin J. Cooney, Wenhai Xie, Ji Xiong, Hu Wang, Xiaodong Zhao, Ji Wu
Publikováno v:
Journal of Advanced Research, Vol 33, Iss , Pp 81-98 (2021)
Introduction: Fate determination of germline stem cells remains poorly understood at the chromatin structure level. Objectives: Our research hopes to develop successful offspring production of ovarian organoids derived from spermatogonial stem cells
Externí odkaz:
https://doaj.org/article/0a5f8e74bf8348f4a6d4d68409dca27b
Autor:
Austin J. Cooney
Publikováno v:
BioTechniques, Vol 24, Iss 1, Pp 30-34 (1998)
Externí odkaz:
https://doaj.org/article/29666d4eea2248799f540224c0a24fc5
Autor:
Ji Xiong, Xinbao Ding, Xiaodong Zhao, Wenhai Xie, Dali Li, Xiaoyong Li, Hu Wang, Austin J. Cooney, Lin Hou, Geng G. Tian, Huacheng Luo, Yunze Yang, Qifeng Lyu, Changliang Hou, Ji Wu
Publikováno v:
Journal of Advanced Research
Journal of Advanced Research, Vol 33, Iss, Pp 81-98 (2021)
Journal of Advanced Research, Vol 33, Iss, Pp 81-98 (2021)
Graphical abstract
Introduction Fate determination of germline stem cells remains poorly understood at the chromatin structure level. Objectives Our research hopes to develop successful offspring production of ovarian organoids derived from sper
Introduction Fate determination of germline stem cells remains poorly understood at the chromatin structure level. Objectives Our research hopes to develop successful offspring production of ovarian organoids derived from sper
Publikováno v:
Stem Cell Research, Vol 31, Iss, Pp 27-30 (2018)
A skin biopsy was obtained from a 14-year-old female patient with a history of Myelomeningocele. Dermal fibroblasts were isolated and reprogrammed with Sendai virus (SeV) vectors encoding OCT3/4, SOX2, KLF4, and c-MYC. The generated induced Pluripote