Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Austin D Royster"'
Autor:
Zekun Wang, Songyang Ren, Qiming Li, Austin D Royster, Lei Lin, Sichen Liu, Safder S Ganaie, Jianming Qiu, Sheema Mir, Mohammad A Mir
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10, p e1010007 (2021)
Hantavirus nucleocapsid protein (NP) inhibits protein kinase R (PKR) dimerization by an unknown mechanism to counteract its antiviral responses during virus infection. Here we demonstrate that NP exploits an endogenous PKR inhibitor P58IPK to inhibit
Externí odkaz:
https://doaj.org/article/fc347b4fe5674dde86684e65fbe767f4
Autor:
Lei lin, Qiming Li, Mohammad A. Mir, Austin D. Royster, Zekun Wang, Songyang Ren, Safder S. Ganaie, Jianming Qiu, Sichen Liu, Sheema Mir
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 10, p e1010007 (2021)
PLoS Pathogens, Vol 17, Iss 10, p e1010007 (2021)
Hantavirus nucleocapsid protein (NP) inhibits protein kinase R (PKR) dimerization by an unknown mechanism to counteract its antiviral responses during virus infection. Here we demonstrate that NP exploits an endogenous PKR inhibitor P58IPK to inhibit
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0260143 (2021)
PLoS ONE
PLoS ONE
The protein aggregation is one of the major challenges of the biotechnological industry, especially in the areas of development and commercialization of successful protein-based drug products. The inherent high aggregation tendency of proteins during
Autor:
Jacquelyn Ragan, Sheema Mir, Nicholas A. Almeida, Lea O’Brien, Subbiah Jeeva, Sharon Wu, Austin D. Royster, Ariga Tahmasian Sevarany, Fion Chan, Aljona Leka, Adrain Velasquez, Mohammad A. Mir
Publikováno v:
The Journal of biological chemistry. 294(13)
Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne Nairovirus that causes severe hemorrhagic fever with a mortality rate of up to 30% in certain outbreaks worldwide. The virus has wide endemic distribution. There is no effective antiviral