Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Austen Pimm"'
Autor:
Austen Pimm, Philip J. Kocienski, Philip Ashworth, Richard Bell, Pawel Jankowski, Brian Broadbelt
Publikováno v:
Synthesis. 1995:199-206
Autor:
Stephen Connolly, Nigel Gensmantel, Peter Hamley, Richard P. Harrison, Paul Hartopp, Nigel Boughton-Smith, Timothy Nicholas Birkinshaw, Antonio Mete, Haydn Beaton, Sally L. Cooper, Austen Pimm, David Cheshire, Gunilla Andersson, Alan V. Wallace, Anders Åberg, Paul D. Leeson, John Dixon, David Cox, Timothy Jon Luker, Helena Käck, Ian Millichip, Steve St-Gallay, David J. Nicholls, Anne Cooper, Glen Andrews, Tony R. Cook
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(8)
By careful analysis of experimental X-ray ligand crystallographic protein data across several inhibitor series we have discovered a novel, potent and selective series of iNOS inhibitors exemplified by compound 8.
Autor:
Mark Furber, Cladingboel David, Janice Bent, M.J. Robertson, Timothy Jon Luker, Lilian Alcaraz, Michael Mortimore, Moya Caffrey, Martin Braddock, Robert J. Riley, Celine Laurent, Peter J. H. Webborn, Frank Ince, Philip Thorne, Jill Theaker, John Collington, Elizabeth Kinchin, Mandy Lawson, Austen Pimm, Armin Beyerbach, Richard J. Weaver, Keith Bowers, David Donald, Malbinder Fagura, Paul Willis, Nicola Roberts
Publikováno v:
Journal of medicinal chemistry. 50(24)
A novel series of antagonists of the human P2X7 receptor is described. Modification of substituents enabled identification of compounds selective for the rat P2X7 receptor and provides useful pharmacological tools for evaluation of the role of P2X7 i
Publikováno v:
Synlett. 1992:886-888