Výsledky vyhledávání - "Aurore Colomar"

Le statut immun de la cellule de Schwann : quels rôles pour le récepteur P2X7 ?

Autor: Aurore Colomar, Vincent Marty, Thierry Amédée, Patricia Parnet, Chantal Combe, Chantal Médina

Publikováno v: Journal de la Société de Biologie. 197:113-122

Le systeme nerveux peripherique (SNP) presente des barrieres structurales et une absence de drainage lymphatique qui limitent fortement l’acces des molecules et des cellules immunitaires du systeme immunitaire. De plus, le SNP possede la capacite d

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https://doi.org/10.1051/jbio/2003197020113

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Risk of QT prolongation and torsade de pointes associated with exposure to hydroxyzine: re-evaluation of an established drug

Autor: Jean-Pierre Valentin, Christopher Peters, Annie Delaunois, Rossen Boev, Victor S. Sloan, Aurore Colomar, Anne-Françoise Schlit, J. W. G. Bentz, Luca Cariolato, Branderley Claudio

Publikováno v: Pharmacology Research & Perspectives

Several noncardiac drugs have been linked to cardiac safety concerns, highlighting the importance of post‐marketing surveillance and continued evaluation of the benefit‐risk of long‐established drugs. Here, we examine the risk of QT prolongatio

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https://doi.org/10.1002/prp2.309

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ATP stimulation of P2X7receptors activates three different ionic conductances on cultured mouse Schwann cells

Autor: Thierry Amédée, Aurore Colomar

Publikováno v: European Journal of Neuroscience. 14:927-936

Extracellular ATP, by acting on P2 purinergic receptors, is a potent mediator of cell-to-cell communication both within and between the nervous and the immune systems. We show here by patch-clamp recording, fluorescent dye uptake and immunocytochemis

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https://doi.org/10.1046/j.0953-816x.2001.01714.x

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Spontaneous neuronal activity in organotypic cultures of mouse dorsal root ganglion leads to upregulation of calcium channel expression on remote Schwann cells

Autor: Jonathan A. Coles, Thierry Amédée, Jean-Marc Israel, Aurore Colomar, Claire Beaudu‐Lange

Publikováno v: Glia. 29:281-287

It is well established that neurons regulate the properties of both central and peripheral glial cells. Some of these neuro-glial interactions are modulated by the pattern of neuronal electrical activity. In the present work, we asked whether blockin

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https://doi.org/10.1002/(sici)1098-1136(20000201)29:3<281::aid-glia9>3.0.co

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Comparison of four in silico models to predict cardiac action potential effects and proarrhythmia liability

Autor: Annie Delaunois, Aurore Colomar, Jean-Pierre Valentin

Publikováno v: Journal of Pharmacological and Toxicological Methods. 81:350

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ce0447bd17feef7fd6984299a2a8b019
https://doi.org/10.1016/j.vascn.2016.02.050

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Impedance based Assay on iPS cardiomyocytes: An efficient way of discriminating between cardioactive and non cardioactive drugs

Autor: Simon Loiodice, Lucille Haen, Benjamin Kopp, Aurore Colomar, Jean-Pierre Valentin, Gaelle Toussaint, Franck A. Atienzar

Publikováno v: Journal of Pharmacological and Toxicological Methods. 81:381

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https://doi.org/10.1016/j.vascn.2016.02.151

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Recent cardiac ion channel data helped to better understand the QT prolongation/Torsades de Pointes risk of hydroxyzine (Atarax®), a first generation antihistamine

Autor: Aurore Colomar, Christopher Peters, Annie Delaunois, Jean-Pierre Valentin, Anne-Françoise Schlit

Publikováno v: Journal of Pharmacological and Toxicological Methods. 81:354

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https://doi.org/10.1016/j.vascn.2016.02.064

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The mouse induced Pluripotent Stem cell-derived cardiomyocytes: Detection of pro-arrhythmia, chronotropy, inotropy and cardiac cell death by RTCA cardio measurement

Autor: Franck A. Atienzar, Gaelle Toussaint, Simon Loiodice, Aurore Colomar, Lucille Haen

Publikováno v: Journal of Pharmacological and Toxicological Methods. 70:351-352

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a8793445fa8892fab7c685c6b27e533b
https://doi.org/10.1016/j.vascn.2014.03.145

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Detection of cardiac liability of UCB-X by novel in vitro and in vivo models

Autor: Marie-Luce Rosseels, Jean-Pierre Valentin, Annie Delaunois, Aurore Colomar

Publikováno v: Journal of Pharmacological and Toxicological Methods. 75:173

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cdccc28b8d53baeca37328d9ebc74940
https://doi.org/10.1016/j.vascn.2015.08.054

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Glial modulation of synaptic transmission at the neuromuscular junction

Autor: Richard Robitaille, Aurore Colomar

Publikováno v: GliaREFERENCES. 47(3)

The neuromuscular junction (NMJ) is a cholinergic synapse that controls muscle contraction. Glial cells, called perisynaptic Schwann cells, surround nerve terminals at the NMJ. Transmitter release induced by repetitive nerve stimulation, elicit a fre

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https://pubmed.ncbi.nlm.nih.gov/15252818

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