Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Aurore Cecile Valfort"'
Autor:
Meghan H. Murray, Aurore Cecile Valfort, Thomas Koelblen, Céline Ronin, Fabrice Ciesielski, Arindam Chatterjee, Giri Babu Veerakanellore, Bahaa Elgendy, John K. Walker, Lamees Hegazy, Thomas P. Burris
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
The nuclear receptor REV-ERBα is a receptor for heme and plays a role in a range of physiological processes. Here, the authors provide the first structure of REV-ERB bound to a synthetic nonporphyrin ligand defining key mechanistic differences to ho
Externí odkaz:
https://doaj.org/article/e9a3baa7b5fa4017822b58a19fb7301d
Autor:
Kristine Griffett, Amina Kameric, Monideepa Sengupta, Arindam Chatterjee, Aurore Cecile-Valfort, Suomia Abuirqeba, Thomas P. Burris, Colin A. Flaveny
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0249316 (2021)
PLoS ONE
PLoS ONE
Alcoholic liver disease (ALD) is responsible for an average of 50.4% and 44.2%of liver disease deaths among males and females respectively. Driven by alcohol misuse, ALD is often reversible by cessation of consumption. However, abstinence programs ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ceec9f88bcbc34b291dc8bcca783ea2
https://doaj.org/article/3ffcc6b6ac274312a88e634223fff00d
https://doaj.org/article/3ffcc6b6ac274312a88e634223fff00d
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
Scientific Reports
Duchenne muscular dystrophy (DMD) is a debilitating X-linked disorder that is fatal. DMD patients lack the expression of the structural protein dystrophin caused by mutations within the DMD gene. The absence of functional dystrophin protein results i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d49f808df5b6002c6e2a22fd407bd7b7
http://link.springer.com/article/10.1038/s41598-017-17496-7
http://link.springer.com/article/10.1038/s41598-017-17496-7
Autor:
Richard J. Di Paolo, Suomia Abuirqeba, Colin A. Flaveny, Jinsong Zhang, Aurore-Cecile Valfort, Arindam Chatterjee, Katherine J. Carpenter, Laurie P. Shornick, Nick Steinauer, Shabnam Majidi, Monideepa Sengupta
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-18 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-18 (2019)
Triple-negative breast cancer (TNBC) is a highly aggressive subtype that is untreatable with hormonal or HER2-targeted therapies and is also typically unresponsive to checkpoint-blockade immunotherapy. Within the tumor microenvironment dysregulated i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d6fc9f8687c925f42e8ec616619d953
https://pubmed.ncbi.nlm.nih.gov/31863071
https://pubmed.ncbi.nlm.nih.gov/31863071
Autor:
Paulette Mezin, Jean-Louis Bessereau, Pierre-Simon Jouk, Judith Melki, Ivo Gut, Loic Quevarec, Manuela D'Alessandro, Aurore-Cecile Valfort, Sandrina Turczynski, Klaus Dieterich, Emanuela Abiusi, Marta Gut
Publikováno v:
Human molecular genetics. 26(20)
Arthrogryposis multiplex congenita (AMC) is a developmental condition characterized by multiple joint contractures resulting from reduced or absent fetal movements. Homozygosity mapping of disease loci combined with whole exome sequencing in a consan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8efd958707a0ff9facf3ba3159deb0f
https://pubmed.ncbi.nlm.nih.gov/29016857
https://pubmed.ncbi.nlm.nih.gov/29016857
Autor:
Katherine Joyce Carpenter, Suomia Abuirqeba, Shabnam Majidi, Monideepa Sengupta, Aurore-Cecile Valfort, Arindam Chatterjee, Richard J DiPaolo, Colin A. Flaveny
Publikováno v:
The Journal of Immunology. 202:137.7-137.7
While immunotherapies have demonstrated success in solid malignancies, they have limited efficacy in triple negative breast cancer (TNBC). The liver-X-receptors (LXR) are modulators of metabolism and are known to inhibit pro-inflammatory (Th17 and Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b4bffe4b9aa501a0124f4150723a5ed
https://doi.org/10.4049/jimmunol.202.supp.137.7
https://doi.org/10.4049/jimmunol.202.supp.137.7
Autor:
Monideepa Sengupta, Suomia Abuirqeba, Amina Kameric, Aurore Cecile-Valfort, Arindam Chatterjee, Kristine Griffett, Thomas P Burris, Colin A Flaveny
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0249316 (2021)
Alcoholic liver disease (ALD) is responsible for an average of 50.4% and 44.2%of liver disease deaths among males and females respectively. Driven by alcohol misuse, ALD is often reversible by cessation of consumption. However, abstinence programs ca
Externí odkaz:
https://doaj.org/article/3ffcc6b6ac274312a88e634223fff00d