Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Aurore, Girardeau"'
Autor:
Meryl Roudaut, Amandine Caillaud, Zied Souguir, Lise Bray, Aurore Girardeau, Antoine Rimbert, Mikaël Croyal, Gilles Lambert, Murielle Patitucci, Gaspard Delpouve, Élodie Vandenhaute, Cédric Le May, Nathalie Maubon, Bertrand Cariou, Karim Si‐Tayeb
Publikováno v:
Bioengineering & Translational Medicine, Vol 9, Iss 4, Pp n/a-n/a (2024)
Abstract The liver plays a key role in the metabolism of lipoproteins, controlling both production and catabolism. To accelerate the development of new lipid‐lowering therapies in humans, it is essential to have a relevant in vitro study model avai
Externí odkaz:
https://doaj.org/article/53835cc8b72d4f2bb753a350085e434f
Autor:
Michelle Geryk, Robin Canac, Virginie Forest, Pierre Lindenbaum, Aurore Girardeau, Manon Baudic, Estelle Baron, Anne Bibonne, Caroline Chariau, Florence Kyndt, Richard Redon, Jean-Jacques Schott, Jean-Baptiste Gourraud, Julien Barc, Flavien Charpentier
Publikováno v:
Stem Cell Research, Vol 77, Iss , Pp 103396- (2024)
Mutations in the DES gene, which encodes the intermediate filament desmin, lead to desminopathy, a rare disease characterized by skeletal muscle weakness and different forms of cardiomyopathies associated with cardiac conduction defects and arrhythmi
Externí odkaz:
https://doaj.org/article/fdac19c886c84554b341c4fcc1d7e11d
Autor:
Amandine Caillaud, Lise Bray, Aurore Girardeau, Zoé Begué-Racapé, Lucie Vince, Murielle Patitucci, Cédric Le May, Gilles Lambert, Bertrand Cariou, Antoine Rimbert
Publikováno v:
Stem Cell Research, Vol 72, Iss , Pp 103205- (2023)
Elevated circulating lipoprotein(a) (Lp(a)) is a genetically determined risk factor for coronary artery disease and aortic valve stenosis (Tsimikas, 2017). Importantly, the LPA gene, which encodes the apolipoprotein(a) (protein-component of Lp(a)), i
Externí odkaz:
https://doaj.org/article/e345a600cf6a4dfa9de0005f00980a21
Autor:
Amandine Caillaud, Antoine Lévêque, Aurélie Thédrez, Aurore Girardeau, Robin Canac, Lise Bray, Manon Baudic, Julien Barc, Nathalie Gaborit, Guillaume Lamirault, Betty Gardie, Salam Idriss, Antoine Rimbert, Cédric Le May, Bertrand Cariou, Karim Si-Tayeb
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101680- (2022)
Summary: This manuscript proposes an efficient and reproducible protocol for the generation of genetically modified human induced pluripotent stem cells (hiPSCs) by genome editing using CRISPR-Cas9 technology. Here, we describe the experimental strat
Externí odkaz:
https://doaj.org/article/5abbb31c95e14d87806374946c01203d
Autor:
Bastien Cimarosti, Robin Canac, Stephan De Waard, Aurore Girardeau, Anne Gaignerie, Aude Derevier, Virginie Forest, Michel Ronjat, Hervé Le Marec, Jean-Baptiste Gourraud, Patricia Lemarchand, Michel De Waard, Guillaume Lamirault, Nathalie Gaborit
Publikováno v:
Stem Cell Research, Vol 60, Iss , Pp 102688- (2022)
Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT) is an exercise and emotional stress-induced life-threatening inherited heart rhythm disorder, characterized by an abnormal cellular calcium homeostasis. Most reported cases have been linked
Externí odkaz:
https://doaj.org/article/480ef971c3f441c0b9fa5c25d89e4e0e
Autor:
Lise Bray, Amandine Caillaud, Aurore Girardeau, Murielle Patitucci, Cédric Le May, Bertrand Cariou, Antoine Rimbert
Publikováno v:
Stem Cell Research, Vol 60, Iss , Pp 102721- (2022)
Dyslipidemia is a key modifiable causal risk factor involved in the development of atherosclerotic cardiovascular disease. Recently, the G protein-coupled receptor 146 (GPR146), a member of the G-coupled protein receptors’ family, has been shown to
Externí odkaz:
https://doaj.org/article/91ae641bbee14723a56feea438de6d5d
Autor:
Aurore Girardeau, Diane Atticus, Robin Canac, Bastien Cimarosti, Amandine Caillaud, Caroline Chariau, Floriane Simonet, Bertrand Cariou, Flavien Charpentier, Jean-Baptiste Gourraud, Vincent Probst, Nadjet Belbachir, Laurence Jesel, Patricia Lemarchand, Julien Barc, Richard Redon, Nathalie Gaborit, Guillaume Lamirault
Publikováno v:
Stem Cell Research, Vol 59, Iss , Pp 102647- (2022)
Four human induced pluripotent stem cell (hiPSC) lines have been generated from healthy control European donors, and validated. This resource represents a useful tool for stem cell-based research, as references for developmental studies and disease m
Externí odkaz:
https://doaj.org/article/e451cd47ad734a8bbbb3a51ae1564c13
Autor:
Bastien Cimarosti, Robin Canac, Aurore Girardeau, Marine Arnaud, Quentin Francheteau, Vincent Probst, Patricia Lemarchand, Richard Redon, Jean-Baptiste Gourraud, Nathalie Gaborit, Guillaume Lamirault
Publikováno v:
Stem Cell Research, Vol 59, Iss , Pp 102649- (2022)
Catecholamine-induced QT prolongation (CIQTP) is an inherited cardiac disease characterized by a normal baseline ECG and a risk of sudden cardiac death by ventricular arrhythmia due to a QT prolongation that only appears during catecholergic stimulat
Externí odkaz:
https://doaj.org/article/ba425c90cc124dbaa0b8e2ae90ef0d8d
Autor:
Robin Canac, Amandine Caillaud, Bastien Cimarosti, Aurore Girardeau, Hanan Hamamy, Bruno Reversade, Carine Bonnard, Zeina R. Al Sayed, Laurent David, Jeremie Poschmann, Patricia Lemarchand, Guillaume Lamirault, Nathalie Gaborit
Publikováno v:
Stem Cell Research, Vol 58, Iss , Pp 102627- (2022)
Studies on animal models have shown that Irx5 is an important regulator of cardiac development and that it regulates ventricular electrical repolarization gradient in the adult heart. Mutations in IRX5 have also been linked in humans to cardiac condu
Externí odkaz:
https://doaj.org/article/a5200d83fcab486da903e7e399073f5b
Autor:
Robin Canac, Bastien Cimarosti, Aurore Girardeau, Virginie Forest, Pierre Olchesqui, Jeremie Poschmann, Richard Redon, Patricia Lemarchand, Nathalie Gaborit, Guillaume Lamirault
Publikováno v:
Cells, Vol 11, Iss 23, p 3915 (2022)
Human heart development is governed by transcription factor (TF) networks controlling dynamic and temporal gene expression alterations. Therefore, to comprehensively characterize these transcriptional regulations, day-to-day transcriptomic profiles w
Externí odkaz:
https://doaj.org/article/0f5392ee75f94c23b2d93d9fe2ffa188