Výsledky vyhledávání - "Aurore, Drolez"

Akademický článek

Accumulation of GD1α Ganglioside in MDA-MB-231 Breast Cancer Cells Expressing ST6GalNAc V

Autor: Sandy Vandermeersch, Jorick Vanbeselaere, Clément P. Delannoy, Aurore Drolez, Caroline Mysiorek, Yann Guérardel, Philippe Delannoy, Sylvain Julien

Publikováno v: Molecules, Vol 20, Iss 4, Pp 6913-6924 (2015)

α-Series gangliosides define a particular sub-class of glycosphingolipids containing sialic acid α2,6-linked to GalNAc residue that was isolated as a minor compound from the brain. The sialyltransferase ST6GalNAc V was cloned from mouse brain and s

Externí odkaz: https://doaj.org/article/b85c989996e74798844de49b07e9ffed

Zobrazit plný text záznamu

Akademický článek

Selection of a Relevant In Vitro Blood-Brain Barrier Model to Investigate Pro-Metastatic Features of Human Breast Cancer Cell Lines.

Autor: Aurore Drolez, Elodie Vandenhaute, Sylvain Julien, Fabien Gosselet, Joy Burchell, Roméo Cecchelli, Philippe Delannoy, Marie-Pierre Dehouck, Caroline Mysiorek

Publikováno v: PLoS ONE, Vol 11, Iss 3, p e0151155 (2016)

Around 7-17% of metastatic breast cancer patients will develop brain metastases, associated with a poor prognosis. To reach the brain parenchyma, cancer cells need to cross the highly restrictive endothelium of the Blood-Brain Barrier (BBB). As treat

Externí odkaz: https://doaj.org/article/af3e4f32df7340c6bb490641ca9e8edc

Zobrazit plný text záznamu

Adapting coculture in vitro models of the blood–brain barrier for use in cancer research: maintaining an appropriate endothelial monolayer for the assessment of transendothelial migration

Autor: Elodie Vandenhaute, Fabien Gosselet, Marie-Pierre Dehouck, Aurore Drolez, Caroline Mysiorek, Emmanuel Sevin

Publikováno v: Laboratory Investigation
Laboratory Investigation, Nature Publishing Group, 2016, 96 (5), pp.588-598. ⟨10.1038/labinvest.2016.35⟩

International audience; Although brain metastases are the most common brain tumors in adults, there are few treatment options in this setting. To colonize the brain, circulating tumor cells must cross the blood-brain barrier (BBB), which is situated

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3673229c0383189ffb7706d7db87457
https://hal-univ-artois.archives-ouvertes.fr/hal-02510335

Zobrazit plný text záznamu

ST6GALNAC5 Expression Decreases the Interactions between Breast Cancer Cells and the Human Blood-Brain Barrier

Autor: Aurore Drolez, Philippe Delannoy, Clément Philippe Delannoy, Sylvain Julien, Marie-Pierre Dehouck, Elodie Vandenhaute, Fabien Gosselet, Roméo Cecchelli, Justine H. Dewald, Caroline Mysiorek

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2015, 17 (8), pp.1309. ⟨10.3390/ijms17081309⟩
International Journal of Molecular Sciences, MDPI, 2015, 17 (8), ⟨10.3390/ijms17081309⟩
International Journal of Molecular Sciences; Volume 17; Issue 8; Pages: 1309
International Journal of Molecular Sciences, Vol 17, Iss 8, p 1309 (2016)
International Journal of Molecular Sciences, 2015, 17 (8), pp.1309. ⟨10.3390/ijms17081309⟩

International audience; The ST6GALNAC5 gene that encodes an α2,6-sialyltransferase involved in the biosynthesis of α-series gangliosides, was previously identified as one of the genes that mediate breast cancer metastasis to the brain. We have show

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cf4066ecb6cbcaff60b0006df95d99d
https://hal.archives-ouvertes.fr/hal-01358166/document

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání