Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Aurora Lopez"'
Autor:
David Hou, Hanxiao Wan, Joshua L. Katz, Si Wang, Brandyn A. Castro, Gustavo I. Vazquez-Cervantes, Victor A. Arrieta, Silpol Dhiantravan, Hinda Najem, Aida Rashidi, Tzu-yi Chia, Tarlan Arjmandi, Jimena Collado, Leah Billingham, Aurora Lopez-Rosas, Yu Han, Adam M. Sonabend, Amy B. Heimberger, Peng Zhang, Jason Miska, Catalina Lee-Chang
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Understanding the spatial relationship and functional interaction of immune cells in glioblastoma (GBM) is critical for developing new therapeutics that overcome the highly immunosuppressive tumor microenvironment. Our study showed that B and T cells
Externí odkaz:
https://doaj.org/article/6ecf574030ed40ef851a4a0c31efda84
Autor:
Peng Zhang, Aida Rashidi, Junfei Zhao, Caylee Silvers, Hanxiang Wang, Brandyn Castro, Abby Ellingwood, Yu Han, Aurora Lopez-Rosas, Markella Zannikou, Crismita Dmello, Rebecca Levine, Ting Xiao, Alex Cordero, Adam M. Sonabend, Irina V. Balyasnikova, Catalina Lee-Chang, Jason Miska, Maciej S. Lesniak
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Glioblastoma is an immunologically cold tumour, with poor CD8 + T cell infiltration and enrichment in immunosuppressive tumour-associated myeloid cells. Here, the authors generate a bispecific lipid nanoparticle targeting CD47 and PD-L1, combined wit
Externí odkaz:
https://doaj.org/article/70608dccfdaf43fd8925f863fd3fe044
Autor:
Aurora Lopez Güeto
Publikováno v:
Ambigua, Iss 5, Pp 40-57 (2018)
Since the foundation of theurbs, the role reserved to Roman women as daughters, wives and mothers demanded morally restrictedbehaviours.In the archaic stage (758b. C.-300 a. C.)marriage usually involvedthe de-parture of thefamily to enter behind the
Externí odkaz:
https://doaj.org/article/e0f7da94a28f40a6b52690d1995bb246
Autor:
Megan E. Muroski, Jason Miska, Alan L. Chang, Peng Zhang, Aida Rashidi, Haley Moore, Aurora Lopez-Rosas, Yu Han, Maciej S. Lesniak
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Fatty acid (FA) metabolism directly influences the functional capabilities of T cells in tumor microenvironments. Thus, developing tools to interrogate FA-uptake by T cell subsets is important for understanding tumor immunosuppression. Herei
Externí odkaz:
https://doaj.org/article/abb432fcf52848cdae2859e8d6b42e95
Autor:
Jason Miska, Catalina Lee-Chang, Aida Rashidi, Megan E. Muroski, Alan L. Chang, Aurora Lopez-Rosas, Peng Zhang, Wojciech K. Panek, Alex Cordero, Yu Han, Atique U. Ahmed, Navdeep S. Chandel, Maciej S. Lesniak
Publikováno v:
Cell Reports, Vol 27, Iss 1, Pp 226-237.e4 (2019)
Summary: The mechanisms by which regulatory T cells (Tregs) migrate to and function within the hypoxic tumor microenvironment are unclear. Our studies indicate that specific ablation of hypoxia-inducible factor 1α (HIF-1α) in Tregs results in enhan
Externí odkaz:
https://doaj.org/article/cbc778c1066448d7b3957bc6d14e521e
Autor:
Ludovico Cantuti-Castelvetri, Hongling Zhu, Maria I. Givogri, Robstein L. Chidavaenzi, Aurora Lopez-Rosas, Ernesto R. Bongarzone
Publikováno v:
Neurobiology of Disease, Vol 46, Iss 2, Pp 325-335 (2012)
Patients with Krabbe disease, a genetic demyelinating syndrome caused by deficiency of galactosyl-ceramidase and the resulting accumulation of galactosyl-sphingolipids, develop signs of a dying-back axonopathy compounded by a deficiency of large-cali
Externí odkaz:
https://doaj.org/article/7c297e586a104e19a1133a0bf254af08
Autor:
Benjamin Smith, Francesca Galbiati, Ludovico Cantuti Castelvetri, Maria I Givogri, Aurora Lopez-Rosas, Ernesto R Bongarzone
Publikováno v:
ASN Neuro, Vol 3 (2011)
Infantile Krabbe disease results in the accumulation of lipid-raft-associated galactosylsphingosine (psychosine), demyelination, neurodegeneration and premature death. Recently, axonopathy has been depicted as a contributing factor in the progression
Externí odkaz:
https://doaj.org/article/4cf86029343e4379877e754b0f24f068
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