Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Aurora, Castellano"'
Autor:
Maria Rita Braghini, Cristiano De Stefanis, Francesca Tiano, Aurora Castellano, Nicolo’ Cicolani, Marco Pezzullo, Valeria Tocco, Marco Spada, Rita Alaggio, Anna Alisi, Paola Francalanci
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundHepatoblastoma (HB) is the most common pediatric hepatic malignancy. Despite the progress in HB treatment, investigating HB pathomechanisms to optimize stratification and therapies remains a focal point to improve the outcome for high-risk
Externí odkaz:
https://doaj.org/article/8bd7b6029ac04845acc9a9b1c3c3f685
Autor:
Giuliano Marchetti, Alessandro Vittori, Marco Cascella, Ilaria Mascilini, Simone Piga, Emiliano Petrucci, Aurora Castellano, Roberta Caruso, Elisa Francia, Francesca Stocchi, Franco Marinangeli, Alessandro Inserra, Sergio Giuseppe Picardo
Publikováno v:
Italian Journal of Pediatrics, Vol 49, Iss 1, Pp 1-8 (2023)
Abstract Background In 2016, we performed a one-day investigation to analyze the prevalence of pain, pain intensity, and pain therapy in the Departments of Surgery and Onco-Hematology of the Ospedale Pediatrico Bambino Gesù. To improve the knowledge
Externí odkaz:
https://doaj.org/article/e2994f4b965844628d23a38ef234538a
Autor:
Flora Cimmino, Annalaura Montella, Matilde Tirelli, Marianna Avitabile, Vito Alessandro Lasorsa, Feliciano Visconte, Sueva Cantalupo, Teresa Maiorino, Biagio De Angelis, Martina Morini, Aurora Castellano, Franco Locatelli, Mario Capasso, Achille Iolascon
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-17 (2022)
Abstract Background FGFR1 regulates cell–cell adhesion and extracellular matrix architecture and acts as oncogene in several cancers. Potential cancer driver mutations of FGFR1 occur in neuroblastoma (NB), a neural crest-derived pediatric tumor ari
Externí odkaz:
https://doaj.org/article/ac047a0c6811417d93f8e3d0fffdff20
Autor:
Ombretta Melaiu, Marco Chierici, Valeria Lucarini, Giuseppe Jurman, Libenzio Adrian Conti, Rita De Vito, Renata Boldrini, Loredana Cifaldi, Aurora Castellano, Cesare Furlanello, Vincenzo Barnaba, Franco Locatelli, Doriana Fruci
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Tumour-infiltrating lymphocytes play a crucial role in neuroblastoma, but their relationship to other immune cells is poorly understood. Here the authors identify the cellular and gene signatures of intratumoural dendritic cells and natural killer ce
Externí odkaz:
https://doaj.org/article/191708cfe4614fcda62e11c1850f8185
Autor:
Valerio Voglino, Giorgio Persano, Alessandro Crocoli, Aurora Castellano, Annalisa Serra, Ugo Giordano, Gian Luigi Natali, Pier Luigi Di Paolo, Cristina Martucci, Alessandra Stracuzzi, Alessandro Inserra
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Background: Neuroblastoma is the most common solid extracranial tumor in children. Patients affected by neuroblastoma are stratified into low, intermediate, and high risk in terms of event-free and overall survival. Some high-risk patients have an ad
Externí odkaz:
https://doaj.org/article/88b22044d91e47e88c3228e5caa30ffb
Autor:
Bruno De Bernardi, Andrea Di Cataldo, Alberto Garaventa, Paolo Massirio, Elisabetta Viscardi, Marta Giorgia Podda, Aurora Castellano, Paolo D’Angelo, Elisa Tirtei, Fraia Melchionda, Simona Vetrella, Francesco De Leonardis, Carmelita D’Ippolito, Annalisa Tondo, Antonella Nonnis, Giovanni Erminio, Anna Rita Gigliotti, Katia Mazzocco, Riccardo Haupt
Publikováno v:
Italian Journal of Pediatrics, Vol 45, Iss 1, Pp 1-14 (2019)
Abstract Background Infants diagnosed with stage 4 s neuroblastoma commonly experience spontaneous disease regression, with few succumbing without response to therapy. We analyzed a large cohort of such infants enrolled in the Italian Neuroblastoma R
Externí odkaz:
https://doaj.org/article/6b02525c4f364f53bdcc59c0a9c931d8
Autor:
Alessandra Dondero, Martina Morini, Davide Cangelosi, Katia Mazzocco, Martina Serra, Grazia Maria Spaggiari, Gianluca Rotta, Annalisa Tondo, Aurora Castellano, Francesca Scuderi, Angela Rita Sementa, Alessandra Eva, Massimo Conte, Alberto Garaventa, Cristina Bottino, Roberta Castriconi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 4 (2021)
Background High-risk neuroblastomas (HR-NBs) are rare, aggressive pediatric cancers characterized by resistance to therapy and relapse in more than 30% of cases, despite using an aggressive therapeutic protocol including targeting of GD2. The mechani
Externí odkaz:
https://doaj.org/article/97b435d8597b4a889e4837c3685e5188
Autor:
Evelina Miele, Angela Di Giannatale, Alessandro Crocoli, Raffaele Cozza, Annalisa Serra, Aurora Castellano, Antonella Cacchione, Maria Giuseppina Cefalo, Rita Alaggio, Maria Debora De Pasquale
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Background and Aims: Pediatric adrenocortical tumors (ACTs) are very rare endocrine neoplasms in childhood. In this study, we performed a retrospective analysis of children with ACT treated at our institution by examining clinical and genetic disease
Externí odkaz:
https://doaj.org/article/5761cfbb5ecc44f1a86d45f758b0c272
Autor:
Marta Colletti, Luigi Tomao, Angela Galardi, Alessandro Paolini, Virginia Di Paolo, Cristiano De Stefanis, Paolo Mascio, Francesca Nazio, Stefania Petrini, Aurora Castellano, Ida Russo, Roberta Caruso, Simone Piga, Rita De Vito, Luisa Pascucci, Hector Peinado, Andrea Masotti, Franco Locatelli, Angela Di Giannatale
Publikováno v:
Journal of Extracellular Vesicles, Vol 9, Iss 1 (2020)
Bone marrow (BM) is the major target organ for neuroblastoma (NB) metastasis and its involvement is associated with poor outcome. Yet, the mechanism by which NB cells invade BM is largely unknown. Tumour microenvironment represents a key element in t
Externí odkaz:
https://doaj.org/article/1b979d2d4bb641ab9a68abfddea478bb
Tumor-infiltrating T cells and PD-L1 expression in childhood malignant extracranial germ-cell tumors
Autor:
Renata Boldrini, Maria Debora De Pasquale, Ombretta Melaiu, Marco Chierici, Giuseppe Jurman, Maria Chiara Benedetti, Nunzio C. Salfi, Aurora Castellano, Paola Collini, Cesare Furlanello, Vito Pistoia, Loredana Cifaldi, Monica Terenziani, Doriana Fruci
Publikováno v:
OncoImmunology, Vol 8, Iss 2 (2019)
Although pediatric malignant extracranial germ-cell tumors (meGCTs) are among the most chemosensitive solid tumors, a group of patients relapse and die of disease. To identify new markers predicting clinical outcome, we examined the prognostic releva
Externí odkaz:
https://doaj.org/article/630e1d8c6f8a4580bd5852303057eeaf