Bridging drug discovery through hierarchical subtractive genomics against asd, trpG, and secY of pneumonia causing MDR Staphylococcus aureus.

Autor: Wisal A; Department of Chemistry, Islamia College Peshawar, Peshawar-KP, 25000, Pakistan., Saeed N; Department of Medical Laboratory Technology, Riphah International University Lahore, Lahore, Pakistan., Aurongzeb M; Department of Applied Sciences, FEST, Hamdard University, Karachi, 74600, Pakistan., Shafique M; Department of Pharmaceutical Sciences, College of Pharmacy, Shaqra University, Shaqra, Saudi Arabia., Sohail S; Department of Chemistry, Islamia College Peshawar, Peshawar-KP, 25000, Pakistan., Anwar W; Department of Microbiology, Rehman Medical Institute, Peshawar-KP, 25000, Pakistan., Basharat Z; Alpha Genomics Pvt. Ltd, Islamabad, Pakistan., Irfan M; JRC Genome Research, International Center for Chemical and Biological Sciences (ICCBS-PCMD), University of Karachi, Karachi, 75270, Pakistan., Ullah A; Department of Chemistry, Islamia College Peshawar, Peshawar-KP, 25000, Pakistan. asad_icp@yahoo.com., Hassan SS; Department of Chemistry, Islamia College Peshawar, Peshawar-KP, 25000, Pakistan. hassanchemist83@gmail.com.; JRC Genome Research, International Center for Chemical and Biological Sciences (ICCBS-PCMD), University of Karachi, Karachi, 75270, Pakistan. hassanchemist83@gmail.com.

Publikováno v: Molecular genetics and genomics : MGG [Mol Genet Genomics] 2024 Mar 13; Vol. 299 (1), pp. 34. Date of Electronic Publication: 2024 Mar 13.

Exploring the extrachromosomal plasmid rDNA of Naegleria fowleri AY27 genotype II: A human brain-eating amoeba via high-throughput sequencing.

Autor: Aurongzeb M; Department of Biotechnology, Faculty of Engineering Sciences & Technology, Hamdard University, Karachi, 74600, Pakistan., Talha Malik HM; Alpha Genomics Private limited, Islamabad, Pakistan., Jahanzaib M; JRC Genome Research, PCMD, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan., Hassan SS; JRC Genome Research, PCMD, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan., Rashid Y; Department of Biochemistry, University of Karachi, Karachi, 75270, Pakistan. yasmeen.rashid@uok.edu.pk., Aziz T; Laboratory of Animal Health Food Hygiene and Quality, Department of Agriculture, University of Ioannina, Arta, 47132, Greece., Alharbi M; Department of Pharmacology and Toxicology College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.

Publikováno v: BMC medical genomics [BMC Med Genomics] 2024 May 07; Vol. 17 (1), pp. 125. Date of Electronic Publication: 2024 May 07.

Exploring and targeting potential druggable antimicrobial resistance targets ArgS, SecY, and MurA in Staphylococcus sciuri with TCM inhibitors through a subtractive genomics strategy.

Autor: Khan A; Department of Chemistry, Islamia College Peshawar, Peshawar, 25000, KP, Pakistan., Sohail S; Department of Chemistry, Islamia College Peshawar, Peshawar, 25000, KP, Pakistan., Yaseen S; Abbasi Shaheed Hospital, Karachi Medical and Dental College, Karachi, Pakistan., Fatima S; Department of Microbiology, University of Balochistan, Quetta, Balochistan, Pakistan., Wisal A; Department of Chemistry, Islamia College Peshawar, Peshawar, 25000, KP, Pakistan., Ahmed S; Abbasi Shaheed Hospital, Karachi Medical and Dental College, Karachi, Pakistan., Nasir M; Dr. Panjwani Center for Molecular Medicine, International Center for Chemical and Biological Sciences (ICCBS-PCMD), University of Karachi, Karachi, 75270, Pakistan., Irfan M; Dr. Panjwani Center for Molecular Medicine, International Center for Chemical and Biological Sciences (ICCBS-PCMD), University of Karachi, Karachi, 75270, Pakistan., Karim A; Dr. Panjwani Center for Molecular Medicine, International Center for Chemical and Biological Sciences (ICCBS-PCMD), University of Karachi, Karachi, 75270, Pakistan., Basharat Z; Alpha Genomics (Private) Limited, Islamabad, 44710, Pakistan., Khan Y; Dr. Panjwani Center for Molecular Medicine, International Center for Chemical and Biological Sciences (ICCBS-PCMD), University of Karachi, Karachi, 75270, Pakistan., Aurongzeb M; Faculty of Engineering Sciences & Technology, Hamdard University, Karachi, 74600, Pakistan., Raza SK; Faculty of Rehabilitation and Allied Health Sciences (FRAHS), Riphah International University, Faisalabad, Pakistan., Alshahrani MY; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, P.O. Box 61413, Abha, 9088, Saudi Arabia., Morel CM; Centre for Technological Development in Health (CDTS), Oswaldo Cruz Foundation (Fiocruz), Building 'Expansão', 8Th Floor Room 814, Av. Brasil 4036 - Manguinhos, Rio de Janeiro, RJ, 21040-361, Brazil. carlos.morel@cdts.fiocruz.br., Hassan SS; Dr. Panjwani Center for Molecular Medicine, International Center for Chemical and Biological Sciences (ICCBS-PCMD), University of Karachi, Karachi, 75270, Pakistan. hassanchemist83@gmail.com.; Centre for Technological Development in Health (CDTS), Oswaldo Cruz Foundation (Fiocruz), Building 'Expansão', 8Th Floor Room 814, Av. Brasil 4036 - Manguinhos, Rio de Janeiro, RJ, 21040-361, Brazil. hassanchemist83@gmail.com.

Publikováno v: Functional & integrative genomics [Funct Integr Genomics] 2023 Jul 26; Vol. 23 (3), pp. 254. Date of Electronic Publication: 2023 Jul 26.

Awareness is the best option to control.

Publikováno v: Pulse International. 9/14/2013, Vol. 14 Issue 17, p2-3. 2p.

Genomic landscape of the emerging XDR Salmonella Typhi for mining druggable targets clpP, hisH, folP and gpmI and screening of novel TCM inhibitors, molecular docking and simulation analyses.

Autor: Afzal M; Department of Health and Biological Sciences, Abasyn University Peshawar, Peshawar, KP, 25000, Pakistan., Hassan SS; Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan. hassanchemist83@gmail.com.; Centre for Technological Development in Health (CDTS), Oswaldo Cruz Foundation (Fiocruz), Building 'Expansão', 8th floor room 814, Av. Brasil 4036 - Manguinhos, Rio de Janeiro, RJ, 21040-361, Brazil. hassanchemist83@gmail.com.; Jamil-Ur-Rehman Center for Genome Research, PCMD-ICCBS, University of Karachi, Karachi, Sindh, 75270, Pakistan. hassanchemist83@gmail.com., Sohail S; Department of Chemistry, Islamia College Peshawar, Peshawar, KP, 25000, Pakistan., Camps I; Laboratório de Modelagem Computacional, LaModel, Instituto de Ciências Exatas - ICEx. Universidade Federal de Alfenas - UNIFAL-MG, Alfenas, Minas Gerais, Brazil.; High Performance & Quantum Computing Labs, Waterloo, Canada., Khan Y; Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan., Basharat Z; Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan., Karim A; Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan., Aurongzeb M; Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan., Irfan M; Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, 75270, Pakistan., Salman M; Department of Health and Biological Sciences, Abasyn University Peshawar, Peshawar, KP, 25000, Pakistan., Morel CM; Centre for Technological Development in Health (CDTS), Oswaldo Cruz Foundation (Fiocruz), Building 'Expansão', 8th floor room 814, Av. Brasil 4036 - Manguinhos, Rio de Janeiro, RJ, 21040-361, Brazil. carlos.morel@cdts.fiocruz.br.

Publikováno v: BMC microbiology [BMC Microbiol] 2023 Jan 21; Vol. 23 (1), pp. 25. Date of Electronic Publication: 2023 Jan 21.