Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Auriol C Purdie"'
Autor:
Kathryn Wright, Kumudika de Silva, Karren M Plain, Auriol C Purdie, Tamika A Blair, Iain G Duggin, Warwick J Britton, Stefan H Oehlers
Publikováno v:
PLoS Pathogens, Vol 17, Iss 4, p e1009186 (2021)
Pathogenic mycobacteria actively dysregulate protective host immune signalling pathways during infection to drive the formation of permissive granuloma microenvironments. Dynamic regulation of host microRNA (miRNA) expression is a conserved feature o
Externí odkaz:
https://doaj.org/article/ab2479ec6bef4a43a7ab57ae13d447fa
Autor:
Shyamala Thirunavukkarasu, Karren M Plain, Auriol C Purdie, Richard J Whittington, Kumudika de Silva
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0176400 (2017)
According to most models of mycobacterial infection, inhibition of the pro-inflammatory macrophage immune responses contributes to the persistence of bacteria. Mycobacterium avium subsp. paratuberculosis (MAP) is a highly successful pathogen in cattl
Externí odkaz:
https://doaj.org/article/94925606baab41fdb1d1d3fd6c0a2d16
Autor:
Hannah B. Pooley, Guneet Panag, Karren M. Plain, Kumudika de Silva, Douglas J. Begg, Richard J. Whittington, Auriol C. Purdie
Publikováno v:
Vaccine. 41:274-283
The cell mediated immune response and ability of immune cells to migrate to the site of infection are both key aspects of protection against many pathogens. Mycobacterium avium subsp. paratuberculosis (MAP) is an intracellular pathogen and the causat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a772fe4d908efdf3e0bc483f9ed2b47
https://doi.org/10.1016/j.vaccine.2022.11.018
https://doi.org/10.1016/j.vaccine.2022.11.018
Autor:
Auriol C. Purdie, Karren M. Plain, Hannah Pooley, Douglas J. Begg, Kumudika de Silva, Richard J. Whittington
Publikováno v:
Frontiers in Veterinary Science. 9
A critical hindrance in the development of effective vaccine strategies to combat infectious disease is lack of knowledge about correlates of protection and of the host responses necessary for successful adaptive immunity. Often vaccine formulations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a69a60ca78feaba1236df594804f023c
https://doi.org/10.3389/fvets.2022.1004237
https://doi.org/10.3389/fvets.2022.1004237
Publikováno v:
Scientific Reports. 12
Pathogenic mycobacteria including Mycobacterium avium subsp. paratuberculosis (MAP), the causative agent of Johne’s disease, manipulate host macrophages to persist and cause disease. In mycobacterial infection, highly plastic macrophages, shift bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf03387d767aab27b7a1aff32aeaec0
https://doi.org/10.1038/s41598-022-13503-8
https://doi.org/10.1038/s41598-022-13503-8
Autor:
Stefan H. Oehlers, K. de Silva, Kathryn Wright, Auriol C. Purdie, Karren M. Plain, Warwick J. Britton
Regulation of host microRNA (miRNA) expression is a contested node that controls the host immune response to mycobacterial infection. The host must overcome concerted subversive efforts of pathogenic mycobacteria to launch and maintain a protective i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::398e8a7b5ef4b73b7209ec76d9f8b018
https://doi.org/10.1101/2021.10.07.463594
https://doi.org/10.1101/2021.10.07.463594
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports
Paratuberculosis in ruminants is caused by infection with Mycobacterium avium subspecies paratuberculosis (MAP) however exposure does not predetermine progression to clinical disease. The pathogenesis incorporates a subclinical phase during which MAP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f7e550adf18eadac6e14198e82f6bf4
http://link.springer.com/article/10.1038/s41598-019-44670-w
http://link.springer.com/article/10.1038/s41598-019-44670-w
Publikováno v:
Microbial Pathogenesis. 130:44-53
Johne's disease is a chronic wasting disease of ruminants caused by Mycobacterium avium subspecies paratuberculosis (MAP). Closely related pathogenic mycobacteria such as M. tuberculosis are capable of altering host lipid metabolism, highlighting the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::887ec05e8910be6d96e147db23791b5e
https://doi.org/10.1016/j.micpath.2019.02.031
https://doi.org/10.1016/j.micpath.2019.02.031
Autor:
Hannah B. Pooley, Richard J. Whittington, Douglas J. Begg, Auriol C. Purdie, Karren M. Plain, Kumudika de Silva
Publikováno v:
Veterinary Immunology and Immunopathology. 252:110482
Systemic immunisation delivered subcutaneously is currently used to control paratuberculosis, a chronic enteritis of ruminants caused by Mycobacterium avium subspecies paratuberculosis (MAP). These vaccines do not provide complete protection and a sm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f38eac124526dd7ac639ee34777db0cb
https://doi.org/10.1016/j.vetimm.2022.110482
https://doi.org/10.1016/j.vetimm.2022.110482
Autor:
Kumudika de Silva, Karren M. Plain, Warwick J. Britton, Iain G. Duggin, Kathryn Wright, Stefan H. Oehlers, Auriol C. Purdie, Tamika A. Blair
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 4, p e1009186 (2021)
PLoS Pathogens, Vol 17, Iss 4, p e1009186 (2021)
Pathogenic mycobacteria actively dysregulate protective host immune signalling pathways during infection to drive the formation of permissive granuloma microenvironments. Dynamic regulation of host microRNA (miRNA) expression is a conserved feature o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef23bf90ae3e131d0ba530a68d646070
https://hdl.handle.net/10453/149779
https://hdl.handle.net/10453/149779