The alpha7-nicotinic receptor contributes to gp120-induced neurotoxicity: implications in HIV-associated neurocognitive disorders

Autor: Bryan Morales-Vargas, Manuel Delgado-Vélez, Coral M. Capó-Vélez, Jose G. Grajales-Reyes, José A. Lasalde-Dominicci, Carlos A. Báez-Pagán, Aurian Garcia-Gonzalez, Bismark Madera, Orestes Quesada

Publikováno v: Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)

Currently, there are no specific therapies to treat HIV-1 associated neurocognitive disorders (HAND). The HIV-1 envelope, gp120, induces neuropathological changes similar to those in HAND patients; furthermore, it triggers an upregulation of the α7-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98ebdc345ddbce68ed386ca49dbf82e2
http://europepmc.org/articles/PMC5788855

The distribution of recombination repair genes is linked to information content in bacteria

Autor: Steven E. Massey, L. Vicens, M. Alicea, Aurian Garcia-Gonzalez

Publikováno v: Gene. 528(2)

The concept of a ‘proteomic constraint’ proposes that the information content of the proteome exerts a selective pressure to reduce mutation rates, implying that larger proteomes produce a greater selective pressure to evolve or maintain DNA repa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c9dbdf6de29103a7b4a9ff28f11f46
https://pubmed.ncbi.nlm.nih.gov/23796800

Abstract 3200: HPV status influences the survival of HNSCC patients: A consideration for the TNM staging system

Autor: Francisco J. Ruiz-Fullana, Juan Trinidad-Pinedo, Germán L. Vélez-Reyes, Aurian Garcia, Adriana Baez

Publikováno v: Cancer Research. 71:3200-3200

Objective: Head and neck cancers are a heterogeneous group of malignancies, affecting various sites with differing prognoses. Accurate and reliable stratification of head and neck squamous cell carcinomas (HNSCC) for prediction of outcomes continues

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::09372e25a1e109353f86979b0c1bb998
https://doi.org/10.1158/1538-7445.am2011-3200

mTORC2-AKT signaling to ATP-citrate lyase drives brown adipogenesis and de novo lipogenesis.

Autor: Martinez Calejman, C., Trefely, S., Entwisle, S. W., Luciano, A., Jung, S. M., Hsiao, W., Torres, A., Hung, C. M., Li, H., Snyder, N. W., Villén, J., Wellen, K. E., Guertin, D. A.

Publikováno v: Nature Communications; 1/29/2020, Vol. 11 Issue 1, p1-16, 16p

The Impact of a Modular Robotic Total Mesorectal Excision Training Program on Perioperative and Oncological Outcomes in Robotic Rectal Cancer Surgery.

Autor: Stefan S; Department of Colorectal Surgery, Portsmouth Hospitals University NHS Trust, Portsmouth, United Kingdom., Piozzi GN; Department of Colorectal Surgery, Portsmouth Hospitals University NHS Trust, Portsmouth, United Kingdom., Tejedor P; Department of Colorectal Surgery, Portsmouth Hospitals University NHS Trust, Portsmouth, United Kingdom., Liao CCL; Colorectal Department, East and North Hertfordshire NHS Trust, Lister Hospital, Stevenage, United Kingdom., Ahmad A; Colorectal Department, Basildon and Thurrock University Hospital, Basildon, United Kingdom., Ahmad NZ; Department of Surgery, University Hospital Limerick, Limerick, Ireland., Naqvi SAH; Department of Colorectal Surgery, Portsmouth Hospitals University NHS Trust, Portsmouth, United Kingdom., Heald RJ; Pelican Cancer Foundation, Basingstoke, Hampshire, United Kingdom., Khan JS; Department of Colorectal Surgery, Portsmouth Hospitals University NHS Trust, Portsmouth, United Kingdom.; Faculty of Science and Health, University of Portsmouth, Portsmouth, United Kingdom.

Publikováno v: Diseases of the colon and rectum [Dis Colon Rectum] 2024 Nov 01; Vol. 67 (11), pp. 1485-1494. Date of Electronic Publication: 2024 Aug 12.