A systematic review of the development and application of home cage monitoring in laboratory mice and rats

Autor: Pia Kahnau, Paul Mieske, Jenny Wilzopolski, Otto Kalliokoski, Silvia Mandillo, Sabine M. Hölter, Vootele Voikar, Adriana Amfim, Sylvia Badurek, Aleksandra Bartelik, Angela Caruso, Maša Čater, Elodie Ey, Elisabetta Golini, Anne Jaap, Dragan Hrncic, Anna Kiryk, Benjamin Lang, Natasa Loncarevic-Vasiljkovic, Hamid Meziane, Aurelija Radzevičienė, Marion Rivalan, Maria Luisa Scattoni, Nicolas Torquet, Julijana Trifkovic, Brun Ulfhake, Christa Thöne-Reineke, Kai Diederich, Lars Lewejohann, Katharina Hohlbaum

Publikováno v: BMC Biology, Vol 21, Iss 1, Pp 1-23 (2023)

Abstract Background Traditionally, in biomedical animal research, laboratory rodents are individually examined in test apparatuses outside of their home cages at selected time points. However, the outcome of such tests can be influenced by various fa

Externí odkaz: https://doaj.org/article/0f1a3a77ba124af3a174d67a64fb17f7

Analyses of AUC(0–12) and C0 Compliances within Therapeutic Ranges in Kidney Recipients Receiving Cyclosporine or Tacrolimus

Autor: Edmundas Kaduševičius, Aurelija Radzevičienė, Rūta Vaičiūnienė, Pierre Marquet, Rima Maslauskienė, Edgaras Stankevičius

Publikováno v: Journal of Clinical Medicine, Vol 9, Iss 3903, p 3903 (2020)
Journal of Clinical Medicine, Basel : MDPI, 2020, vol. 9, no. 12, 3903, p. 1-23
Journal of Clinical Medicine
Volume 9
Issue 12

The AUC (area under the concentration time curve) is considered the pharmacokinetic exposure parameter best associated with clinical effects. Unfortunately, no prospective studies of clinical outcomes have been conducted in adult transplant recipient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e93fc4169ea5c33bd4b6f59643b421e0
https://www.mdpi.com/2077-0383/9/12/3903

Pharmacokinetic evaluation of MFF in combinations with tacrolimus and cyclosporine. Findings of C0 and AUC

Autor: Rima Maslauskienë, Edmundas Kaduševičius, Aurelija Radzevičienė, Edgaras Stankevičius, Franck Saint-Marcoux, Pierre Marquet

Publikováno v: Medicine
Medicine (Baltimore), Philadelphia : Lippincott Williams & Wilkins, 2020, vol. 99, no. 12, e19441, p. 1-6

We hypothesized that area under the concentration time curve (AUC(0-12)) is more accurate pharmacokinetic predictor vs trough level of mycophenolic acid (C0). Study was performed at the University Hospital of Limoges (France) and included 238 renal r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6aa5f2c1d16089be027ad0a775540f1
https://doi.org/10.1097/md.0000000000019441

Deceased Kidney Donor Biomarkers: Relationship between Delayed Kidney Function and Graft Function Three Years after Transplantation

Autor: Rima Maslauskiene, Ruta Vaiciuniene, Peteris Tretjakovs, Gita Gersone, Aurelija Radzeviciene, Andrejus Bura, Edgaras Stankevicius, Inga Arune Bumblyte

Publikováno v: Diagnostics, Vol 14, Iss 7, p 717 (2024)

With an increasing number of marginal donors, additional methods for the evaluation of cadaveric kidney quality are required. This study aimed to evaluate pretransplant deceased donor serum (s) and urine (u) biomarkers, including neutrophil gelatinas

Externí odkaz: https://doaj.org/article/a966e38dd9154b638332236f6182716a

The Glomerular Filtration Rate Estimators in the Pharmacokinetic Modelling in Acute Kidney Injury: An Observational Study

Autor: Silvijus Abramavicius, Vaidotas Galaune, Agile Tunaityte, Astra Vitkauskiene, Gintautas Gumbrevicius, Aurelija Radzeviciene, Romaldas Maciulaitis

Publikováno v: Antibiotics, Vol 10, Iss 2, p 158 (2021)

The glomerular filtration rate (GFR), according to which the drug dose for patients with chronic kidney disease (CKD) is adjusted, is computed with estimators (eGFR) that are developed specifically for CKD. These particular types of estimators are al

Externí odkaz: https://doaj.org/article/42a1879e96c347648b371d7dafe8e0a2