Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Aurelien A. Serandour"'
Autor:
Laura A. Baker, Holly Holliday, Daniel Roden, Christoph Krisp, Sunny Z. Wu, Simon Junankar, Aurelien A. Serandour, Hisham Mohammed, Radhika Nair, Geetha Sankaranarayanan, Andrew M. K. Law, Andrea McFarland, Peter T. Simpson, Sunil Lakhani, Eoin Dodson, Christina Selinger, Lyndal Anderson, Goli Samimi, Neville F. Hacker, Elgene Lim, Christopher J. Ormandy, Matthew J. Naylor, Kaylene Simpson, Iva Nikolic, Sandra O’Toole, Warren Kaplan, Mark J. Cowley, Jason S. Carroll, Mark Molloy, Alexander Swarbrick
Publikováno v:
Breast Cancer Research, Vol 22, Iss 1, Pp 1-18 (2020)
Abstract Background Basal-like breast cancer (BLBC) is a poorly characterised, heterogeneous disease. Patients are diagnosed with aggressive, high-grade tumours and often relapse with chemotherapy resistance. Detailed understanding of the molecular u
Externí odkaz:
https://doaj.org/article/afb42d75b5ee42f1b156380d241ca612
Autor:
Hisham Mohammed, Clive D’Santos, Aurelien A. Serandour, H. Raza Ali, Gordon D. Brown, Alan Atkins, Oscar M. Rueda, Kelly A. Holmes, Vasiliki Theodorou, Jessica L.L. Robinson, Wilbert Zwart, Amel Saadi, Caryn S. Ross-Innes, Suet-Feung Chin, Suraj Menon, John Stingl, Carlo Palmieri, Carlos Caldas, Jason S. Carroll
Publikováno v:
Cell Reports, Vol 3, Iss 2, Pp 342-349 (2013)
Estrogen receptor-α (ER) is the driving transcription factor in most breast cancers, and its associated proteins can influence drug response, but direct methods for identifying interacting proteins have been limited. We purified endogenous ER using
Externí odkaz:
https://doaj.org/article/82f5e9bc92054011ab7cc4d25829df4b
Autor:
Hisham, Mohammed, I Alasdair, Russell, Rory, Stark, Oscar M, Rueda, Theresa E, Hickey, Gerard A, Tarulli, Aurelien A, Serandour, Aurelien A A, Serandour, Stephen N, Birrell, Alejandra, Bruna, Amel, Saadi, Suraj, Menon, James, Hadfield, Michelle, Pugh, Ganesh V, Raj, Gordon D, Brown, Clive, D'Santos, Jessica L L, Robinson, Grace, Silva, Rosalind, Launchbury, Charles M, Perou, John, Stingl, Carlos, Caldas, Wayne D, Tilley, Jason S, Carroll
Publikováno v:
Nature. 523(7560)
Progesterone receptor (PR) expression is used as a biomarker of oestrogen receptor-α (ERα) function and breast cancer prognosis. Here we show that PR is not merely an ERα-induced gene target, but is also an ERα-associated protein that modulates i
Autor:
Hélène Jakobczyk, Lydie Debaize, Benoit Soubise, Stéphane Avner, Jérémie Rouger-Gaudichon, Séverine Commet, Yan Jiang, Aurélien A. Sérandour, Anne-Gaëlle Rio, Jason S. Carroll, Christian Wichmann, Michael Lie-a-Ling, Georges Lacaud, Laurent Corcos, Gilles Salbert, Marie-Dominique Galibert, Virginie Gandemer, Marie-Bérengère Troadec
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-17 (2021)
Abstract Background B Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) is the most common pediatric cancer. Identifying key players involved in proliferation of BCP-ALL cells is crucial to propose new therapeutic targets. Runt Related Transcript
Externí odkaz:
https://doaj.org/article/3e5be24cee0f4d4db6d0258b58f9a08b
Autor:
Joséphine Briand, Aurélien A. Sérandour, Arulraj Nadaradjane, Gwenola Bougras-Cartron, Dominique Heymann, Benjamin Ory, François M. Vallette, Pierre-François Cartron
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 22, Iss , Pp 72-83 (2020)
MicroRNAs (miRNAs or miRs) play crucial roles in biological and pathological processes. Some miRNAs also appear as promising biomarkers and therapeutic tools. However, the epitranscriptomic regulation of miRNAs is not yet fully elucidated in all of t
Externí odkaz:
https://doaj.org/article/1923c4a8e922482c889c4a8688391f88
Autor:
Fabrice Chatonnet, Amandine Pignarre, Aurélien A. Sérandour, Gersende Caron, Stéphane Avner, Nicolas Robert, Alboukadel Kassambara, Audrey Laurent, Maud Bizot, Xabier Agirre, Felipe Prosper, José I. Martin-Subero, Jérôme Moreaux, Thierry Fest, Gilles Salbert
Publikováno v:
Haematologica, Vol 105, Iss 3 (2020)
Cell identity relies on the cross-talk between genetics and epigenetics and their impact on gene expression. Oxidation of 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) is the first step of an active DNA demethylation process occurring ma
Externí odkaz:
https://doaj.org/article/3f5c35394af14794af1956e6002ceedc
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 20, p 7571 (2020)
Due to the spectacular number of studies focusing on epigenetics in the last few decades, and particularly for the last few years, the availability of a chronology of epigenetics appears essential. Indeed, our review places epigenetic events and the
Externí odkaz:
https://doaj.org/article/308fae3f02604ca3bbfd13439df1ce6b