Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Aurelie Tomczak"'
Autor:
Aurelie Tomczak, Jonathan M. Mortensen, Rainer Winnenburg, Charles Liu, Dominique T. Alessi, Varsha Swamy, Francesco Vallania, Shane Lofgren, Winston Haynes, Nigam H. Shah, Mark A. Musen, Purvesh Khatri
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract Gene Ontology (GO) enrichment analysis is ubiquitously used for interpreting high throughput molecular data and generating hypotheses about underlying biological phenomena of experiments. However, the two building blocks of this analysis —
Externí odkaz:
https://doaj.org/article/22ec44186f434485be70d5c0e2be2183
Autor:
Caroline Stellmach, Julian Sass, Bernd Auber, Martin Boeker, Thomas Wienker, Andrew J Heidel, Manuela Benary, Simon Schumacher, Stephan Ossowski, Frederick Klauschen, Yvonne Möller, Rita Schmutzler, Arsenij Ustjanzew, Patrick Werner, Aurelie Tomczak, Thimo Hölter, Sylvia Thun
Publikováno v:
Journal of the American Medical Informatics Association
Objective The objective was to develop a dataset definition, information model, and FHIR® specification for key data elements contained in a German molecular genomics (MolGen) report to facilitate genomic and phenotype integration in electronic heal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3ae3b0b0491672d8b97d091f4ff541d
https://hdl.handle.net/21.11116/0000-000D-2B80-221.11116/0000-000D-2B7E-7
https://hdl.handle.net/21.11116/0000-000D-2B80-221.11116/0000-000D-2B7E-7
Autor:
Aurelie Tomczak, Christoph Springfeld, Michael T. Dill, De-Hua Chang, Daniel Kazdal, Ursula Wagner, Arianeb Mehrabi, Antje Brockschmidt, Tom Luedde, Patrick Naumann, Albrecht Stenzinger, Peter Schirmacher, Thomas Longerich
Publikováno v:
British journal of cancer. 127(9)
Background Advanced cholangiocarcinoma has a poor prognosis. Molecular targeted approaches have been proposed for patients after progression under first-line chemotherapy treatment. Here, molecular profiling of intrahepatic cholangiocarcinoma in comb
Autor:
Cecilia, Mascia, Francesca, Frexia, Paolo, Uva, Gianluigi, Zanetti, Luca, Pireddu, Gideon, Giacomelli, Christina, Jaeger-Schmidt, Aurelie, Tomczak, Simon, Schumacher, Florian, Kraecher, Roland, Eils, Silje, Ljosland Bakke, Heather, Leslie
Publikováno v:
Studies in health technology and informatics. 270
Current high-throughput sequencing technologies allow us to acquire entire genomes in a very short time and at a relatively sustainable cost, thus resulting in an increasing diffusion of genetic test capabilities, in specialized clinical laboratories
Autor:
Aurelie Tomczak, Jana Sontheimer, David Drechsel, Rainer Hausdorf, Marc Gentzel, Andrej Shevchenko, Stefanie Eichler, Karim Fahmy, Frank Buchholz, M Teresa Pisabarro
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36151 (2012)
Chemokines are small secreted proteins with important roles in immune responses. They consist of a conserved three-dimensional (3D) structure, so-called IL8-like chemokine fold, which is supported by disulfide bridges characteristic of this protein f
Externí odkaz:
https://doaj.org/article/a4eb0ef8e9d84e1894eb5f8e19287389
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-7 (2018)
Scientific Reports
Scientific Reports
1AbstractWe found tremendous inequality across gene and protein annotation resources. We observe that this bias leads biomedical researchers to focus on richly annotated genes instead of those with the strongest molecular data. We advocate for resear
Autor:
Apostolos G. Gittis, Philip M. Murphy, David N. Garboczi, Joohee Lee, Aurelie Tomczak, Kavita Singh
Publikováno v:
Cytokine. 96:238-246
Cytokine-like protein 1 (CYTL1) is a small widely expressed secreted protein lacking significant primary sequence homology to any other known protein. CYTL1 expression appears to be highest in the hematopoietic system and in chondrocytes; however, ma
Autor:
Shane Lofgren, Varsha Swamy, Dominique T. Alessi, Rainer Winnenburg, Charles Liu, Purvesh Khatri, Jonathan M. Mortensen, Winston A. Haynes, Aurelie Tomczak, Nigam H. Shah, Mark A. Musen, Francesco Vallania
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Gene Ontology (GO) enrichment analysis is ubiquitously used for interpreting high throughput molecular data and generating hypotheses about underlying biological phenomena of experiments. However, the two building blocks of this analysis — the onto
Interpretation of biological experiments changes with evolution of Gene Ontology and its annotations
Autor:
Varsha Swamy, Shane Lofgren, Jonathan M. Mortensen, Rainer Winnenburg, Nigam H. Shah, Charles Liu, Mark A. Musen, Francesco Vallania, Winston A. Haynes, Purvesh Khatri, Aurelie Tomczak, Dominique T. Alessi
Gene Ontology (GO) enrichment analysis is ubiquitously used for interpreting high throughput molecular data and generating hypotheses about underlying biological phenomena of experiments. However, the two building blocks of this analysis — the onto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba5ce87f1279c06429b1128ee31c861c
Autor:
Andrea B. Keefer, Athulaprabha Murthi, Susan Gottesman, Zonglin Hu, Stephen H. Leppla, Aurelie Tomczak, Rodolfo Ghirlando, Apostolos G. Gittis, David N. Garboczi, Catherine E. Vrentas
Publikováno v:
Protein Science. 24:1808-1819
Hfq proteins in Gram-negative bacteria play important roles in bacterial physiology and virulence, mediated by binding of the Hfq hexamer to small RNAs and/or mRNAs to post-transcriptionally regulate gene expression. However, the physiological role o