Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Aurelie Orliac"'
Autor:
Janine Cossy, Sarah Rioton, Roselyne Bidault, Aurelie Orliac, Domingo Gomez Pardo, Zeina Antoun
Publikováno v:
Organic Letters. 17:2916-2919
3-Substituted 2-(trifluoromethyl)piperidines B were synthesized by ring expansion of (trifluoromethyl)prolinols A, which were obtained from L-proline via an aziridinium intermediate C. The ring opening of the (trifluoromethyl)aziridinium intermediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c39cef70713996470e10922fea7c39d2
https://doi.org/10.1021/acs.orglett.5b01084
https://doi.org/10.1021/acs.orglett.5b01084
Publikováno v:
Organic Letters. 15:902-905
Amides were produced from carboxylic acids and amines by using XtalFluor-E as an activator. Even poorly reactive carboxylic acids can be transformed to amides. In addition, optically active amines and/or carboxylic acids were not epimerized/racemized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e973d077bbf52a7f2ca1bf3a1758c74f
https://doi.org/10.1021/ol400045d
https://doi.org/10.1021/ol400045d
Autor:
Aurelie Orliac, Roselyne Bidault, Sarah Rioton, Janine Cossy, Domingo Gomez Pardo, Zeina Antoun
Publikováno v:
ChemInform. 46
The straightforward regio- and diastereoselective title reaction allows for the synthesis of a broad range of 3-substituted 2-(trifluoromethyl)piperidines which are formed via ring-opening of a (trifluoromethyl)aziridinium intermediate by various ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c78d13bfef118547271f99145023115
https://doi.org/10.1002/chin.201545159
https://doi.org/10.1002/chin.201545159
Autor:
Janine Cossy, Santosh S. Kulkarni, Julie Routier, Fabienne Burgat Charvillon, Agnes Bombrun, Wolfgang H. B. Sauer, Domingo Gomez Pardo, Aurelie Orliac
Publikováno v:
ChemInform. 45
The study of the physical properties of the novel compounds reveal that fluorine atoms decrease the pKa and modulate the lipophilicity of aminopiperidines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf861ca9dd99c6f2b3bbaaba24de7a65
https://doi.org/10.1002/chin.201437161
https://doi.org/10.1002/chin.201437161
Publikováno v:
ChemInform. 44
Aromatic and aliphatic carboxylic acids are easily converted into the corresponding amides by reaction with various amines in the presence of XtalFluor-E (XTFE) as an activator.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0f2b822fa8d63d4ccc814cb3f2d9534c
https://doi.org/10.1002/chin.201329035
https://doi.org/10.1002/chin.201329035
Autor:
Santosh S. Kulkarni, Domingo Gomez Pardo, Aurelie Orliac, Wolfgang H. B. Sauer, Julie Routier, Agnes Bombrun, Janine Cossy, Fabienne Burgat Charvillon
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 20(13)
The enantioselective syntheses of 3-amino-5-fluoropiperidines and 3-amino-5,5-difluoropiperidines were developed using the ring enlargement of prolinols to access libraries of 3-amino- and 3-amidofluoropiperidines. The study of the physicochemical pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394442356055d2ab59e5e99bc1d58714
https://pubmed.ncbi.nlm.nih.gov/24532344
https://pubmed.ncbi.nlm.nih.gov/24532344
Publikováno v:
ChemInform. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58fd138ac3b9368bc73302f691646266
https://doi.org/10.1002/chin.199243132
https://doi.org/10.1002/chin.199243132