Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Aurelie Lenaerts"'
Autor:
Aurelie Lenaerts, Iwo Kucinski, Ward Deboutte, Marta Derecka, Pierre Cauchy, Thomas Manke, Berthold Göttgens, Rudolf Grosschedl
Publikováno v:
Journal of Experimental Medicine
Funder: Max-Planck-Gesellschaft
Hematopoietic stem cells (HSCs) and multipotent progenitors (MPPs) generate all cells of the blood system. Despite their multipotency, MPPs display poorly understood lineage bias. Here, we examine whether lineage-
Hematopoietic stem cells (HSCs) and multipotent progenitors (MPPs) generate all cells of the blood system. Despite their multipotency, MPPs display poorly understood lineage bias. Here, we examine whether lineage-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c42f52b7b459682827a6d900c3d331
Autor:
Rebecca Hannah, Rudolf Grosschedl, Iwo Kucinski, Nicola K. Wilson, Aurelie Lenaerts, Berthold Göttgens, Sarah Kinston, Pierre Cauchy
Publikováno v:
The EMBO Journal
Recent advances in molecular profiling provide descriptive datasets of complex differentiation landscapes including the haematopoietic system, but the molecular mechanisms defining progenitor states and lineage choice remain ill‐defined. Here, we e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a10cfcf144a8620603b560c8539b931
Publikováno v:
Experimental Hematology. 88:S69-S70
Hematopoietic stem cells (HSCs) continually decide to either self-renew or differentiate. In this study we explore the role of lineage-specific transcription factors in HSC cell fate decisions, in particular Early B cell Factor 1 (EBF1) which orchest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9c735f909bae1f9af285f6f3927063b
https://doi.org/10.1016/j.exphem.2020.09.114
https://doi.org/10.1016/j.exphem.2020.09.114
Autor:
Aurelie Lenaerts, Berthold Göttgens, Sarah Kinston, Rebecca Hannah, Rudolf Grosschedl, Nicola K. Wilson, Pierre Cauchy, Iwo Kucinski
Publikováno v:
Experimental Hematology. 88:S43-S44
Recent breakthroughs in single cell technology have delivered maps of cell states together with their differentiation journeys at unprecedented resolution and scale. However, despite great progress in network inference methods, our understanding of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea6969913fe955984e2bebc97a67a8d3
https://doi.org/10.1016/j.exphem.2020.09.039
https://doi.org/10.1016/j.exphem.2020.09.039
Autor:
Aurelie Lenaerts, Pandelakis A. Koni, Stephanie Humblet-Baron, John S. Barber, Adrian Liston, Carlos P. Roca
Dendritic cells (DCs) are a key cell type in the initiation of the adaptive immune response. Recently, an additional role for DCs in suppressing myeloproliferation was discovered. Myeloproliferative disorder (MPD) was observed in murine studies with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13cc9dceedb70a7ce16144a26e34f1fc
https://lirias.kuleuven.be/handle/123456789/628962
https://lirias.kuleuven.be/handle/123456789/628962
Publikováno v:
Experimental Hematology. 53:S86
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffb6bdbef299c13b1c83423369173f9a
https://doi.org/10.1016/j.exphem.2017.06.194
https://doi.org/10.1016/j.exphem.2017.06.194