Zobrazeno 1 - 10
of 217
pro vyhledávání: '"Aurelie Fabre"'
Autor:
Helena C. Bartels, Sodiq Hameed, Constance Young, Myriam Nabhan, Paul Downey, Kathleen M. Curran, Janet McCormack, Aurelie Fabre, Walter Kolch, Vadim Zhernovkov, Donal J. Brennan
Publikováno v:
npj Women's Health, Vol 2, Iss 1, Pp 1-9 (2024)
Abstract Placenta Accreta Spectrum (PAS) and pre-eclampsia are obstetric disorders associated with significant maternal morbidity and mortality. As pre-eclampsia is characterised by shallow placental invasion and PAS by abnormally deep invasion, we s
Externí odkaz:
https://doaj.org/article/1b137a68beec4c83b97d9f8a9c00b698
Autor:
Kevin Purves, Hannah Brown, Ruth Haverty, Andrew Ryan, Laura L. Griffin, Janet McCormack, Sophie O’Reilly, Patrick W. Mallon, Virginie Gautier, Joseph P. Cassidy, Aurelie Fabre, Michael J. Carr, Gabriel Gonzalez, Simone Ciuti, Nicola F. Fletcher
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 8, Pp 1609-1620 (2024)
SARS-CoV-2 can infect wildlife, and SARS-CoV-2 variants of concern might expand into novel animal reservoirs, potentially by reverse zoonosis. White-tailed deer and mule deer of North America are the only deer species in which SARS-CoV-2 has been doc
Externí odkaz:
https://doaj.org/article/ae21f0b7eb5a4d8a82457a952e0ca72b
Autor:
Joseph A. Bell, Elizabeth R. Davies, Christopher J. Brereton, Milica Vukmirovic, James J.W. Roberts, Kerry Lunn, Leanne Wickens, Franco Conforti, Robert A. Ridley, Jessica Ceccato, Lucy N. Sayer, David A. Johnston, Andres F. Vallejo, Aiman Alzetani, Sanjay Jogai, Ben G. Marshall, Aurelie Fabre, Luca Richeldi, Phillip D. Monk, Paul Skipp, Naftali Kaminski, Emily Offer, Yihua Wang, Donna E. Davies, Mark G. Jones
Publikováno v:
Cell Reports Medicine, Vol 5, Iss 9, Pp 101695- (2024)
Summary: Matrix stiffening by lysyl oxidase-like 2 (LOXL2)-mediated collagen cross-linking is proposed as a core feedforward mechanism that promotes fibrogenesis. Failure in clinical trials of simtuzumab (the humanized version of AB0023, a monoclonal
Externí odkaz:
https://doaj.org/article/28bf070de21f4af1b6319da757012509
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Cutaneous melanoma can be a most challenging neoplasm of high lethality, in part due to its extreme heterogeneity and characteristic aggressive and invasive nature. Indeed, its moniker ‘the great masquerader’ reflects that not all melanomas are c
Externí odkaz:
https://doaj.org/article/c0857677738a46c3934ddef35d783fd9
Autor:
Hannah Fleming, Simon M. Clifford, Aoife Haughey, Roisin MacDermott, Niall McVeigh, Gerard M. Healy, Lisa Lavelle, Suhny Abbara, David J. Murphy, Aurelie Fabre, Edward McKone, Cormac McCarthy, Marcus Butler, Peter Doran, David A. Lynch, Michael P. Keane, Jonathan D. Dodd
Publikováno v:
European Radiology Experimental, Vol 4, Iss 1, Pp 1-9 (2020)
Abstract Background Differentiating combined pulmonary fibrosis with emphysema (CPFE) from pure emphysema can be challenging on high-resolution computed tomography (HRCT). This has antifibrotic therapy implications. Methods Twenty patients with suspe
Externí odkaz:
https://doaj.org/article/794ef4dc5054410bba24f85b7d86f2e6
Pseudohypoxic HIF pathway activation dysregulates collagen structure-function in human lung fibrosis
Autor:
Christopher J Brereton, Liudi Yao, Elizabeth R Davies, Yilu Zhou, Milica Vukmirovic, Joseph A Bell, Siyuan Wang, Robert A Ridley, Lareb SN Dean, Orestis G Andriotis, Franco Conforti, Lennart Brewitz, Soran Mohammed, Timothy Wallis, Ali Tavassoli, Rob M Ewing, Aiman Alzetani, Benjamin G Marshall, Sophie V Fletcher, Philipp J Thurner, Aurelie Fabre, Naftali Kaminski, Luca Richeldi, Atul Bhaskar, Christopher J Schofield, Matthew Loxham, Donna E Davies, Yihua Wang, Mark G Jones
Publikováno v:
eLife, Vol 11 (2022)
Extracellular matrix (ECM) stiffening with downstream activation of mechanosensitive pathways is strongly implicated in fibrosis. We previously reported that altered collagen nanoarchitecture is a key determinant of pathogenetic ECM structure-functio
Externí odkaz:
https://doaj.org/article/c0c5b337cbd6410caef8f61e40897d8b
Autor:
Cormac O’Brien, John A. Duignan, Margaret Gleeson, Orla O’Carroll, Alessandro N. Franciosi, Dermot O’Toole, Aurelie Fabre, Rachel K. Crowley, Cormac McCarthy, Jonathan D. Dodd, David J. Murphy
Publikováno v:
Diagnostics, Vol 12, Iss 12, p 3096 (2022)
Objectives: Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) occurs due to abnormal proliferation of pulmonary neuroendocrine cells. We hypothesized that performing a quantitative analysis of airway features on chest CT may reve
Externí odkaz:
https://doaj.org/article/3e6beb8385924ecdb4622662c11ec349
Publikováno v:
Medicina, Vol 58, Iss 3, p 412 (2022)
Since commercial development in 2003, the usage of modern electronic cigarette (e-cigarette) continues to increase amongst people who have never smoked, ex-smokers who have switched to e-cigarettes, and dual-users of both conventional cigarettes and
Externí odkaz:
https://doaj.org/article/e540e32985fa42b1b3334212d69bd596
Publikováno v:
Breathe, Vol 16, Iss 2 (2020)
Lymphangioleiomyomatosis (LAM) is a diffuse cystic lung disease. There are two main types of LAM: sporadic, and LAM associated with the tuberous sclerosis complex (TSC), which is caused by mutations in the TSC1 and TSC2 genes. LAM is characterised by
Externí odkaz:
https://doaj.org/article/0bc9b0b853f14e8b8216f03952c0d178
Autor:
Ciara O’Connor, Ciaran Farrell, Aurelie Fabre, Donna Eaton, Karen Redmond, David G. McSharry, John B. Conneely, Conor J. Shields, Jim J. Egan, Margaret M. Hannan
Publikováno v:
Medical Mycology Case Reports, Vol 21, Iss , Pp 30-33 (2018)
Invasive fungal infections in immunosuppressed transplant patients are associated with significant morbidity and mortality. We present a case of splenic mucormycosis post-double lung transplant, presenting as uncontrolled near-fatal upper gastrointes
Externí odkaz:
https://doaj.org/article/4946f7eb6cc4430989ec599e78b55c96