Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Aurelie Desgardin"'
Autor:
Koosha Paydary, Aurelie Desgardin, Chih-Yi Liao, Ardaman Shergill, Natalie Marie Reizine, Stephanie Moya, Bryan Peterson, Katherine Reyes, Chanelle Robinzine, Belen Martinez-Caro Aguado, Christine Racette, Elena Ignatiev, Anu Radha Neerukonda, Yuan Ji, Blase N. Polite, Daniel V.T. Catenacci
Publikováno v:
Journal of Clinical Oncology. 40:316-316
316 Background: 5FU, Ox, Iri, and Tax are each active in upper GI cancers. Triplet cytotoxic therapies (txs) improved survival compared to doublets/singlets. However, combination of all 4 agents (FOLFOXIRITAX) has not been studied. UGT1A1 polymorphis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a205a4e957d3bd1cc52f2c29ae8567f
https://doi.org/10.1200/jco.2022.40.4_suppl.316
https://doi.org/10.1200/jco.2022.40.4_suppl.316
Autor:
Tolulope O Rosanwo, Eun-Hee Shim, Sreedharan Kartha, Aurelie Desgardin, Stephen M. Jane, John M. Cunningham, Tatiana Abramova
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 10, p e46482 (2012)
PLoS ONE, Vol 7, Iss 10, p e46482 (2012)
Kruppel-like factor 1(KLF1) is a hematopoietic-specific zinc finger transcription factor essential for erythroid gene expression. In concert with the transacting factor GATA1, KLF1 modulates the coordinate expression of the genes encoding the multi-e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb46e6db5da8d415e992f186fd32eeaa
http://europepmc.org/articles/PMC3463598
http://europepmc.org/articles/PMC3463598
Autor:
Andrew Rosner, Stephen X. Skapek, Lauren E. Roach, Ryan C. Widau, Aurelie Desgardin, Anna Zelivianskaia, Tatiana Abramova, Caroline Y. Sung, Karen M. Bachmeyer, John M. Cunningham, Yanbin Zheng
Publikováno v:
Molecular and cellular biology. 32(21)
In addition to cancer surveillance, p19(Arf) plays an essential role in blocking signals stemming from platelet-derived growth factor receptor β (Pdgfrβ) during eye development, but the underlying mechanisms have not been clear. We now show that wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56cb30e0af992a55f3e40853878b65d1
https://pubmed.ncbi.nlm.nih.gov/22907756
https://pubmed.ncbi.nlm.nih.gov/22907756
Publikováno v:
Blood. 118:2094-2094
Abstract 2094 Krüppel-like factor 1 (KLF1) is a zinc finger-encoding transcription factor that recognizes CACC elements, and is essential for maximal erythroid-specific gene transcription. Several critical mechanisms dependent on KLF1 and required
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a53b29916611e41e7aecaea2bd79a170
https://doi.org/10.1182/blood.v118.21.2094.2094
https://doi.org/10.1182/blood.v118.21.2094.2094
Publikováno v:
Blood. 118:3189-3189
Abstract 3189 Binding of the Krüppel-like Factor 1 (KLF1) to the β-globin gene promoter is required for developmental stage-specific chromatin remodeling and transcriptional initiation. Interaction with a long-range enhancer, the Locus Control Reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48df7378b2631566b51455ff5d44d26e
https://doi.org/10.1182/blood.v118.21.3189.3189
https://doi.org/10.1182/blood.v118.21.3189.3189
Autor:
John M. Cunningham, Eun-Hee Shim, Valerie M. Jansen, Tatiana Abramova, Shaji Ramachandran, Stephen M. Jane, Aurelie Desgardin
Publikováno v:
Blood. 114:461-461
Abstract 461 Krüppel-like factor 1 (KLF1) is essential for erythroid gene expression. Key molecular mechanisms modulated by this transacting factor have been elucidated at the b-globin locus. KLF1 has been associated with recruitment of SWI/SNF and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::673a7feed648ee9ede236ffaccda7f8e
https://doi.org/10.1182/blood.v114.22.461.461
https://doi.org/10.1182/blood.v114.22.461.461
Autor:
Xinan Holly Yang, Meiyi Li, Bin Wang, Wanqi Zhu, Aurelie Desgardin, Kenan Onel, Jill de Jong, Jianjun Chen, Luonan Chen, Cunningham, John M.
Publikováno v:
BMC Bioinformatics; 2015, Vol. 16 Issue 1, p1-21, 21p, 3 Diagrams, 4 Charts, 2 Graphs
Autor:
Shaji Ramachandran, Eun-Hee Shim, Tatiana Abramova, Valerie M. Jansen, Vishwas Parekh, Aurelie Desgardin, Stephen M. Jane, John M. Cunningham
Publikováno v:
Blood. 112:132-132
The zinc finger-encoding transacting factor EKLF binds key regulatory elements of many erythroid-specific genes, and is essential for definitive erythropoiesis. Mice lacking this factor (EKLF−/−) die of anemia by E15.5 of gestation, failing to ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::baa3fe6474ec951c1b1ea01f94c566c8
https://doi.org/10.1182/blood.v112.11.132.132
https://doi.org/10.1182/blood.v112.11.132.132
Autor:
Stephen M. Jane, Aurelie Desgardin, Shaji Ramachandran, Vishwas Parekh, Valerie M. Jansen, John M. Cunningham, Jin He
Publikováno v:
Blood Cells, Molecules, and Diseases. 38:134
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b2b43ece4a390031f82e18b2a57403c
https://doi.org/10.1016/j.bcmd.2006.10.036
https://doi.org/10.1016/j.bcmd.2006.10.036
Autor:
Jin He, John M. Cunningham, Vishwas Parekh, Stephen M. Jane, Shaji Ramachandran, Aurelie Desgardin, Valerie M. Jansen
Publikováno v:
Blood. 108:365-365
Binding of EKLF to the proximal promoter CACC motif is essential for high-level tissue-specific β-globin gene expression. More recent studies have demonstrated that EKLF regulates expression of other erythroid-specific genes, suggesting a broad role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22b66a575105fbc30d0ccd0e836bd3d8
https://doi.org/10.1182/blood.v108.11.365.365
https://doi.org/10.1182/blood.v108.11.365.365