Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Aurelie, Guislain"'
Autor:
Fiamma Salerno, Aurelie Guislain, Julian J. Freen-Van Heeren, Benoit P. Nicolet, Howard A. Young, Monika C. Wolkers
Publikováno v:
OncoImmunology, Vol 8, Iss 2 (2019)
Protective T cell responses against tumors require the production of Interferon gamma (IFN-γ). However, tumor-infiltrating T cells (TILs) gradually lose their capacity to produce IFN-γ and therefore fail to clear malignant cells. Dissecting the und
Externí odkaz:
https://doaj.org/article/3464888a53fa49779ff2a55a060dfefc
Autor:
Iosifina P. Foskolou, Pedro P Cunha, Eleanor Minogue, Benoit P Nicolet, Aurelie Guislain, Christian Jorgensen, Nordin D Zandhuis, Laura Barbieri, David Bargiela, Demitris Nathanael, Petros Tyrakis, Asis Palazon, Monika C Wolkers, Randall S Johnson
SUMMARY2-hydroxyglutarate (2HG) is a by-product of the TCA cycle, and is readily detected in the tissues of healthy individuals. 2HG is found in two enantiomeric forms: S-2HG and R-2HG. Here, we investigate the differential roles of these two enantio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3171c013fcf504e83cd81bb30e0da657
https://doi.org/10.1101/2022.08.18.504372
https://doi.org/10.1101/2022.08.18.504372
Autor:
Floris P. J. van Alphen, Sander Engels, Julian J Freen-van Heeren, Natali Paravinja, Anouk Jurgens, Fiamma Salerno, Aurelie Guislain, Branka Popović, Monika C. Wolkers, Benoit P Nicolet, Maartje van den Biggelaar
Publikováno v:
Cell Reports. 42:112419
Potent T cell responses against infections and malignancies depend on the release of effector molecules, such as pro-inflammatory cytokines. Because effector molecules can be toxic, their production is tightly regulated through post-transcriptional e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::155117c7bd7d733062ba668f56521a84
https://doi.org/10.1016/j.celrep.2023.112419
https://doi.org/10.1016/j.celrep.2023.112419
Publikováno v:
Journal of immunology (Baltimore, Md.. American Association of Immunologists
CD4+ T cells are key contributors in the induction of adaptive immune responses against pathogens. Even though CD4+ T cells are primarily classified as noncytotoxic helper T cells, it has become appreciated that a subset of CD4+ T cells is cytotoxic.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07409d2a6374115af3a827c20e155471
https://doi.org/10.4049/jimmunol.2100138
https://doi.org/10.4049/jimmunol.2100138
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 207(12)
CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::225b3e6dfd5b2e5d1965de247e384bd5
https://pubmed.ncbi.nlm.nih.gov/34782446
https://pubmed.ncbi.nlm.nih.gov/34782446
Publikováno v:
European journal of immunology, 50(7), 949-958. Wiley-VCH Verlag
European Journal of Immunology
European Journal of Immunology
Long‐lasting CD8+ T cell responses are critical in combatting infections and tumors. The pro‐inflammatory cytokine IFN‐γ is a key effector molecule herein. We recently showed that in murine T cells the production of IFN‐γ is tightly regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c47ee9245e1b341d71d15e4a9c3982
Autor:
Benoit P Nicolet, Aurelie Guislain, Julian J Freen-van Heeren, Monika C. Wolkers, Fiamma Salerno, Howard A. Young
Publikováno v:
OncoImmunology, Vol 8, Iss 2 (2019)
Oncoimmunology, 8(2):e1532762. Landes Bioscience
Oncoimmunology, 8(2):e1532762. Landes Bioscience
Protective T cell responses against tumors require the production of Interferon gamma (IFN-γ). However, tumor-infiltrating T cells (TILs) gradually lose their capacity to produce IFN-γ and therefore fail to clear malignant cells. Dissecting the und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f56a696bf2fad6eff9c91ce24daeaffa
https://doi.org/10.1080/2162402x.2018.1532762
https://doi.org/10.1080/2162402x.2018.1532762
Autor:
Fiamma, Salerno, Julian J, Freen-van Heeren, Aurelie, Guislain, Benoit P, Nicolet, Monika C, Wolkers
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 202(3)
Optimal T cell activation requires Ag recognition through the TCR, engagement of costimulatory molecules, and cytokines. T cells can also directly recognize danger signals through the expression of TLRs. Whether TLR ligands have the capacity to provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5ebf505cb8ba68dcb0281bc9be4746d4
https://pubmed.ncbi.nlm.nih.gov/30578304
https://pubmed.ncbi.nlm.nih.gov/30578304
Autor:
Fiamma Salerno, Aurelie Guislain, Monika C. Wolkers, Benoit P Nicolet, Julian J Freen-van Heeren
Publikováno v:
Journal of immunology (Baltimore, Md., 202(3), 714-723. American Association of Immunologists
Optimal T cell activation requires antigen recognition through the T cell receptor (TCR), engagement of costimulatory molecules, and cytokines. T cells can also directly recognize danger signals through the expression of toll-like receptors (TLRs). W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06b05a21a9273fb4d6cc3ed0dbb8d6dc
https://doi.org/10.1101/375840
https://doi.org/10.1101/375840