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pro vyhledávání: '"Aurelia S. Elz"'
Autor:
Janine S. Y. Tam, Elise E. Crame, Aurelia S. Elz, Janet K. Coller, Anthony Wignall, Clive A. Prestidge, Joanne M. Bowen
Publikováno v:
Cancer Chemotherapy and Pharmacology. 90:267-278
Introduction Gastrointestinal mucositis (GIM) is a side effect of high-dose irinotecan (CPT-11), causing debilitating symptoms that are often poorly managed. The role of TLR4 in the development of GIM has been clearly demonstrated. We, therefore, aim
Autor:
Aurelia S. Elz, Natalie L. Trevaskis, Christopher J.H. Porter, Joanne M. Bowen, Clive A. Prestidge
Publikováno v:
Journal of Controlled Release. 341:676-701
Refereed/Peer-reviewed Challenges to effective delivery of drugs following oral administration has attracted growing interest over recent decades. Small molecule drugs (5) and high long-chain triglyceride solubility (> 50 mg/g), properties required t