Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Aurelia Lamanuzzi"'
Autor:
Ilaria Saltarella, Alexander Link, Aurelia Lamanuzzi, Christian Reichen, Joanna Robinson, Concetta Altamura, Assunta Melaccio, Antonio Giovanni Solimando, Roberto Ria, Maria Addolorata Mariggiò, Angelo Vacca, Maria Antonia Frassanito, Jean-François Desaphy
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 176, Iss , Pp 116877- (2024)
Multiple myeloma (MM) progression is closely dependent on cells in the bone marrow (BM) microenvironment, including fibroblasts (FBs) and immune cells. In their BM niche, MM cells adhere to FBs sustaining immune evasion, drug resistance and the undet
Externí odkaz:
https://doaj.org/article/d806c662dad3406092a021c77cd7d934
Autor:
Aurelia Lamanuzzi, Ilaria Saltarella, Antonia Reale, Assunta Melaccio, Antonio Giovanni Solimando, Concetta Altamura, Grazia Tamma, Clelia Tiziana Storlazzi, Doron Tolomeo, Vanessa Desantis, Maria Addolorata Mariggiò, Jean-François Desaphy, Andrew Spencer, Angelo Vacca, Benedetta Apollonio, Maria Antonia Frassanito
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1400 (2023)
Extracellular vesicles (EVs) have emerged as important players in cell-to-cell communication within the bone marrow (BM) of multiple myeloma (MM) patients, where they mediate several tumor-associated processes. Here, we investigate the contribution o
Externí odkaz:
https://doaj.org/article/53691e10e7164ed6be018791decbb9fc
Autor:
Sebastiano Cicco, Vanessa Desantis, Antonio Vacca, Gerardo Cazzato, Antonio G. Solimando, Anna Cirulli, Silvia Noviello, Cecilia Susca, Marcella Prete, Gabriele Brosolo, Cristiana Catena, Aurelia Lamanuzzi, Ilaria Saltarella, Maria Antonia Frassanito, Antonella Cimmino, Giuseppe Ingravallo, Leonardo Resta, Roberto Ria, Monica Montagnani
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
BackgroundTakayasu Arteritis (TAK) increases vascular stiffness and arterial resistance. Atherosclerosis leads to similar changes. We investigated possible differences in cardiovascular remodeling between these diseases and whether the differences ar
Externí odkaz:
https://doaj.org/article/f88e7ee9e06c4fb298af61a4695cbaa4
Autor:
Ilaria Saltarella, Maria Antonia Frassanito, Aurelia Lamanuzzi, Arianna Brevi, Patrizia Leone, Vanessa Desantis, Lucia Di Marzo, Matteo Bellone, Daniele Derudas, Domenico Ribatti, Raffaella Chiaramonte, Maria Teresa Palano, Antonino Neri, Maria Addolorata Mariggiò, Ruggiero Fumarulo, Franco Dammacco, Vito Racanelli, Angelo Vacca, Roberto Ria
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 1, Pp 93-105 (2019)
Interactions of multiple myeloma (MM) cells with endothelial cells (ECs) enhance angiogenesis and MM progression. Here, we investigated the role of Notch signaling in the cross talk between ECs and MM cells enabling angiogenesis. MMECs showed higher
Externí odkaz:
https://doaj.org/article/776e69befcdd433b9391b123de9f954c
Autor:
Ilaria Saltarella, Concetta Altamura, Aurelia Lamanuzzi, Benedetta Apollonio, Angelo Vacca, Maria Antonia Frassanito, Jean-François Desaphy
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7302 (2022)
Ion channels are pore-forming proteins that allow ions to flow across plasma membranes and intracellular organelles in both excitable and non-excitable cells. They are involved in the regulation of several biological processes (i.e., proliferation, c
Externí odkaz:
https://doaj.org/article/dc70998f6c374837b7f26e9a9ecc7d5e
Autor:
Ilaria Saltarella, Aurelia Lamanuzzi, Benedetta Apollonio, Vanessa Desantis, Giulia Bartoli, Angelo Vacca, Maria Antonia Frassanito
Publikováno v:
Cells, Vol 10, Iss 11, p 3185 (2021)
Multiple myeloma (MM) progression closely depends on the bidirectional crosstalk between tumor cells and the surrounding microenvironment, which leads to the creation of a tumor supportive niche. Extracellular vesicles (EVs) have emerged as key playe
Externí odkaz:
https://doaj.org/article/e2f631e438b74a0b991f3529a1f4e3d8
Autor:
Patrizia Leone, Giuseppe Di Lernia, Antonio Giovanni Solimando, Sebastiano Cicco, Ilaria Saltarella, Aurelia Lamanuzzi, Roberto Ria, Maria Antonia Frassanito, Maurilio Ponzoni, Paolo Ditonno, Franco Dammacco, Vito Racanelli, Angelo Vacca
Publikováno v:
OncoImmunology, Vol 8, Iss 1 (2019)
Endothelial cells (EC) line the bone marrow microvasculature and are in close contact with CD8+ T cells that come and go across the permeable capillaries. Because of these intimate interactions, we investigated the capacity of EC to act as antigen-pr
Externí odkaz:
https://doaj.org/article/3dc81a7a2bcb491b9e9463ba880d5515
Autor:
Vanessa Desantis, Ilaria Saltarella, Aurelia Lamanuzzi, Assunta Melaccio, Antonio Giovanni Solimando, Maria Addolorata Mariggiò, Vito Racanelli, Angelo Paradiso, Angelo Vacca, Maria Antonia Frassanito
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9, p 3084 (2020)
MicroRNAs (miRNAs, or miRs) are single-strand short non-coding RNAs with a pivotal role in the regulation of physiological- or disease-associated cellular processes. They bind to target miRs modulating gene expression at post-transcriptional levels.
Externí odkaz:
https://doaj.org/article/55301d2732304554a5a575d0d40a7fe8
Autor:
Ilaria Saltarella, Vanessa Desantis, Assunta Melaccio, Antonio Giovanni Solimando, Aurelia Lamanuzzi, Roberto Ria, Clelia Tiziana Storlazzi, Maria Addolorata Mariggiò, Angelo Vacca, Maria Antonia Frassanito
Publikováno v:
Cells, Vol 9, Iss 1, p 167 (2020)
Daratumumab (Dara) is the first-in-class human-specific anti-CD38 mAb approved for the treatment of multiple myeloma (MM). Although recent data have demonstrated very promising results in clinical practice and trials, some patients do not achieve a p
Externí odkaz:
https://doaj.org/article/1d558859d0ca4f98b97b1d35fb0a4056
Publikováno v:
Haematologica, Vol 103, Iss 1 (2018)
Externí odkaz:
https://doaj.org/article/75500e4fcf01442ebb6d22f6e95b9ff3