Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Aurelia Conte"'
Autor:
Werner Neidhart, Tanja Schulz-Gasch, Armin Ruf, Matthias Nettekoven, Hans Peter Märki, Bernd Kuhn, Daniel Hunziker, Aurelia Conte, Kurt Amrein, Jean Ackermann, Alexander V. Mayweg
Publikováno v:
CHIMIA, Vol 69, Iss 7-8 (2015)
Medicinal chemistry has been transformed by major technological and conceptual innovations over the last three decades: structural biology and bioinformatics, structure and property based molecular design, the concepts of multidimensional optimizatio
Externí odkaz:
https://doaj.org/article/3b529670cd084da4a0e403988df5e367
Autor:
Giorgio Ottaviani, Lin Gao, Simona M. Ceccarelli, Ulrike Obst-Sander, Rodolfo Gasser, Xiaolei Zhang, Michael Paul Myers, Sung-Sau So, Bernd Kuhn, Holger Kühne, Shirley Li, Werner Neidhart, Aurelia Conte, Markus G. Rudolph
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:5092-5097
Dual inhibition of fatty acid binding proteins 4 and 5 (FABP4 and FABP5) is expected to provide beneficial effects on a number of metabolic parameters such as insulin sensitivity and blood glucose levels and should protect against atherosclerosis. St
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c41543e55482f6d90cb5fbe74b2971cc
https://doi.org/10.1016/j.bmcl.2016.08.071
https://doi.org/10.1016/j.bmcl.2016.08.071
Autor:
Jean Ackermann, Werner Neidhart, Hans Peter Märki, Bernd Kuhn, Armin Ruf, Tanja Schulz-Gasch, Daniel Hunziker, Alexander V. Mayweg, Aurelia Conte, Matthias Nettekoven, Kurt Amrein
Publikováno v:
CHIMIA, Vol 69, Iss 7-8 (2015)
Medicinal chemistry has been transformed by major technological and conceptual innovations over the last three decades: structural biology and bioinformatics, structure and property based molecular design, the concepts of multidimensional optimizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fb3f007d3aab3d4854b887b8e02f92f
https://pubmed.ncbi.nlm.nih.gov/28482972
https://pubmed.ncbi.nlm.nih.gov/28482972
Autor:
Constantinos G. Panousis, Cornelia Hertel, Holger Kühne, Fabienne Ricklin, Michael B. Otteneder, Nicole A. Kratochwil, Stephan Röver, Uwe Grether, Robert Narquizian, Jens-Uwe Peters, Henrietta Dehmlow, Aurelia Conte, Dominik Hainzl
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(18)
Pyrido pyrimidinones are selective agonists of the human high affinity niacin receptor GPR109A (HM74A). They show no activity on the highly homologous low affinity receptor GPR109B (HM74). Starting from a high throughput screening hit the in vitro ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fbbe6ec77e64b96783df85cf77d00c5
https://pubmed.ncbi.nlm.nih.gov/20724150
https://pubmed.ncbi.nlm.nih.gov/20724150
Autor:
Aurelia Conte, Jack E. Baldwin, Gareth J. Pritchard, Nageswara Rao Irlapati, Robert M. Adlington, Rodolfo Marquez
Publikováno v:
ChemInform. 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db9f9e23837b8ac4d334d35e770ebc11
https://doi.org/10.1002/chin.200245209
https://doi.org/10.1002/chin.200245209
Autor:
Robert M. Adlington, Aurelia Conte, Gareth J. Pritchard, Rodolfo Marquez, Jack E. Baldwin, Nageswara Rao Irlapati
Publikováno v:
ChemInform. 36
The total synthesis of the naturally occurring kinase inhibitor pyridovericin 1 is reported. A flexible and efficient synthesis has been accomplished in good yield from readily available 2,4-dihydroxypyridine. Pyridovericin is a key intermediate in o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dc4409a0928919aa1ff3b25bd75b9b0
https://doi.org/10.1002/chin.200503216
https://doi.org/10.1002/chin.200503216