Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Aurelia Bourcier"'
Autor:
Delphine Mika, V. Algalarrondo, Valérie Domergue, Aurelia Bourcier, Matthieu Dessillons, Pauline Robert, Kaouter Bouadjel, Jérôme Leroy, Philippe Mateo, Marta Lindner, Florence Lefebvre, Jean-Baptiste Michel, A. Varin, Flavien Charpentier, Rodolphe Fischmeister, Jean Piero Margaria, Jane-Lise Samuel, Ibrahim Bedioune, Sarah Karam, Patrick Lechêne, Susana Gomez, Emilio Hirsch, Françoise Gaudin, Grégoire Vandecasteele, Charlène Coquard, Alessandra Ghigo
Publikováno v:
Circulation
Circulation, American Heart Association, 2020, 142 (2), pp.161-174. ⟨10.1161/CIRCULATIONAHA.119.042573⟩
Circulation, 2020, 142 (2), pp.161-174. ⟨10.1161/CIRCULATIONAHA.119.042573⟩
Circulation, American Heart Association, 2020, 142 (2), pp.161-174. ⟨10.1161/CIRCULATIONAHA.119.042573⟩
Circulation, 2020, 142 (2), pp.161-174. ⟨10.1161/CIRCULATIONAHA.119.042573⟩
Background: The cyclic AMP (adenosine monophosphate; cAMP)-hydrolyzing protein PDE4B (phosphodiesterase 4B) is a key negative regulator of cardiac β-adrenergic receptor stimulation. PDE4B deficiency leads to abnormal Ca 2+ handling and PDE4B is decr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::787623791718c74dce9c7a27212f58c3
http://hdl.handle.net/2318/1765893
http://hdl.handle.net/2318/1765893
Autor:
Marion Barthe, Grégoire Vandecasteele, Jérôme Leroy, Ibrahim Bedioune, Hela Ben Miled, Rodolphe Fischmeister, Patrick Lechêne, Aurelia Bourcier
Publikováno v:
Experimental Physiology
Experimental Physiology, Wiley-Blackwell, 2019, 104 (8), pp.1237-1249. ⟨10.1113/EP087760⟩
Experimental Physiology, Wiley-Blackwell, 2019, 104 (8), pp.1237-1249. ⟨10.1113/EP087760⟩
NEW FINDINGS What is the central question of this study? Can imipramine, an antidepressant agent that is a cationic amphiphilic drug that interferes with the phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2 ) interactions with proteins maintaining th
Autor:
Jean Piero Margaria, Emilio Hirsch, V. Algalarrondo, Grégoire Vandecasteele, Susana Gomez, Alessandra Ghigo, Aurelia Bourcier, Rodolphe Fischmeister, Jérôme Leroy, C. Coquard, A. Varin
Publikováno v:
Archives of Cardiovascular Diseases Supplements. 11:224-225
Chronic beta-AR activation is detrimental because it promotes cardiac remodeling and ultimately leads to heart failure (HF). Multiple cyclic nucleotide phosphodiesterases (PDEs) finely tune beta-AR responses by degrading and compartmentalizing cAMP.